Q6I4E9 (GCP_BACAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	BA_0261, GBAA_0261, BAS0247

Organism

Bacillus anthracis

Taxonomic identifier

1392 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	343 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.
Sequence caution	The sequence AAP24300.1 differs from that shown. Reason: Erroneous initiation. The sequence AAT29344.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 343	343	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303262

Sequences

	Sequence		Length	Mass (Da)
	Q6I4E9 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: E793A7F804FA8CA4	FASTA	343	36,567
	10 20 30 40 50 60 MGEYIMEKNT IILGIETSCD ETAVAVVKNG TEIIANVVAS QIESHKRFGG VVPEIASRHH 70 80 90 100 110 120 VEEITVVLEE ALKEANITFD DIDAIAVTEG PGLVGALLIG VNAAKAVAFA HDIPLVGVHH 130 140 150 160 170 180 IAGHIYANRL VKEVQFPLLS LVVSGGHTEL VYMKEHGSFE VIGETRDDAA GEAYDKVART 190 200 210 220 230 240 LSMPYPGGPH IDRLAHEGKP TIDLPRAWLE PDSYDFSFSG LKSAVINTVH NAKQRGIEIA 250 260 270 280 290 300 PEDLAASFQE SVIDVLVTKA SRAADAYNVK QVLLAGGVAA NKGLRARLET EFAQKENVEL 310 320 330 340 IIPPLSLCTD NAAMIAAAGT IAYEQGKRAT LALNANPGLD IEA

References

[1]	"The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria." Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J. , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M. Nature 423:81-86(2003) [PubMed: 12721629] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames / isolate Porton.
[2]	"Bacillus anthracis comparative genomics." Ravel J., Rasko D.A., Shumway M.F., Jiang L., Cer R.Z., Federova N.B., Wilson M., Stanley S., Decker S., Read T.D., Salzberg S.L., Fraser C.M. Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames ancestor.
[3]	"Complete genome sequence of Bacillus anthracis Sterne." Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H. Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sterne.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016879 Genomic DNA. Translation: AAP24300.1. Different initiation. AE017334 Genomic DNA. Translation: AAT29344.1. Different initiation. AE017225 Genomic DNA. Translation: AAT52582.1.
RefSeq	NP_842814.1. NC_003997.3. YP_016869.1. NC_007530.2.
3D structure databases
ProteinModelPortal	Q6I4E9.
ModBase	Search...
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000009857; EBBACP00000009613; EBBACG00000009849. EBBACT00000016118; EBBACP00000015739; EBBACG00000016110. EBBACT00000021132; EBBACP00000020617; EBBACG00000021123.
GeneID	1084587. 2819394.
GenomeReviews	Gene locus BA_0261 in contig AE016879_GR. Gene locus BAS0247 in contig AE017225_GR. Gene locus GBAA_0261 in contig AE017334_GR.
KEGG	ban:BA_0261. bar:GBAA_0261. bat:BAS0247.
PATRIC	18778056. VBIBacAnt69550_0254.
TIGR	BA_0261. GBAA_0261.
Phylogenomic databases
GeneTree	EBGT00050000002496.
HOGENOM	HBG304663.
OMA	PAVGVHH.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	BANT260799:BAS0247-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_BACAN

Accession

Primary (citable) accession number: Q6I4E9
Secondary accession number(s): Q6KY50, Q81VE7

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	July 19, 2004
Last modified:	January 25, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program