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Protein

Chromosomal replication initiator protein DnaA

Gene

dnaA

Organism
Bacillus thuringiensis subsp. konkukian (strain 97-27)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi151 – 158ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA replication

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chromosomal replication initiator protein DnaAUniRule annotation
Gene namesi
Name:dnaAUniRule annotation
Ordered Locus Names:BT9727_0001
OrganismiBacillus thuringiensis subsp. konkukian (strain 97-27)
Taxonomic identifieri281309 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000001301 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001141301 – 446Chromosomal replication initiator protein DnaAAdd BLAST446

Structurei

3D structure databases

ProteinModelPortaliQ6HQ03.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DnaA family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000235658.
KOiK02313.
OMAiQSKTRKR.

Family and domain databases

CDDicd06571. Bac_DnaA_C. 1 hit.
Gene3Di1.10.1750.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00377. DnaA_bact. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR001957. Chromosome_initiator_DnaA.
IPR020591. Chromosome_initiator_DnaA-like.
IPR018312. Chromosome_initiator_DnaA_CS.
IPR013317. DnaA.
IPR013159. DnaA_C.
IPR024633. DnaA_N_dom.
IPR027417. P-loop_NTPase.
IPR010921. Trp_repressor/repl_initiator.
[Graphical view]
PfamiPF00308. Bac_DnaA. 1 hit.
PF08299. Bac_DnaA_C. 1 hit.
PF11638. DnaA_N. 1 hit.
[Graphical view]
PRINTSiPR00051. DNAA.
SMARTiSM00382. AAA. 1 hit.
SM00760. Bac_DnaA_C. 1 hit.
[Graphical view]
SUPFAMiSSF48295. SSF48295. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00362. DnaA. 1 hit.
PROSITEiPS01008. DNAA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6HQ03-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENISDLWNS ALKELEKKVS KPSYETWLKS TTAHNLKKDV LTITAPNEFA
60 70 80 90 100
RDWLESHYSE LISETLYDLT GAKLAIRFII PQSQAEEEID LPPAKPNAAQ
110 120 130 140 150
DDSNHLPQSM LNPKYTFDTF VIGSGNRFAH AASLAVAEAP AKAYNPLFIY
160 170 180 190 200
GGVGLGKTHL MHAIGHYVIE HNPNAKVVYL SSEKFTNEFI NSIRDNKAVD
210 220 230 240 250
FRNKYRNVDV LLIDDIQFLA GKEQTQEEFF HTFNALHEES KQIVISSDRP
260 270 280 290 300
PKEIPTLEDR LRSRFEWGLI TDITPPDLET RIAILRKKAK AEGLDIPNEV
310 320 330 340 350
MLYIANQIDS NIRELEGALI RVVAYSSLIN KDINADLAAE ALKDIIPNSK
360 370 380 390 400
PKIISIYDIQ KAVGDVYQVK LEDFKAKKRT KSVAFPRQIA MYLSRELTDS
410 420 430 440
SLPKIGEEFG GRDHTTVIHA HEKISKLLKT DTQLQKQVEE INDILK
Length:446
Mass (Da):50,495
Last modified:July 19, 2004 - v1
Checksum:i091F23BD9E059AEF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017355 Genomic DNA. Translation: AAT61466.1.
RefSeqiWP_000428021.1. NC_005957.1.
YP_034361.1. NC_005957.1.

Genome annotation databases

EnsemblBacteriaiAAT61466; AAT61466; BT9727_0001.
GeneIDi2857048.
KEGGibtk:BT9727_0001.
PATRICi18980315. VBIBacThu119411_0001.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017355 Genomic DNA. Translation: AAT61466.1.
RefSeqiWP_000428021.1. NC_005957.1.
YP_034361.1. NC_005957.1.

3D structure databases

ProteinModelPortaliQ6HQ03.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT61466; AAT61466; BT9727_0001.
GeneIDi2857048.
KEGGibtk:BT9727_0001.
PATRICi18980315. VBIBacThu119411_0001.

Phylogenomic databases

HOGENOMiHOG000235658.
KOiK02313.
OMAiQSKTRKR.

Family and domain databases

CDDicd06571. Bac_DnaA_C. 1 hit.
Gene3Di1.10.1750.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00377. DnaA_bact. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR001957. Chromosome_initiator_DnaA.
IPR020591. Chromosome_initiator_DnaA-like.
IPR018312. Chromosome_initiator_DnaA_CS.
IPR013317. DnaA.
IPR013159. DnaA_C.
IPR024633. DnaA_N_dom.
IPR027417. P-loop_NTPase.
IPR010921. Trp_repressor/repl_initiator.
[Graphical view]
PfamiPF00308. Bac_DnaA. 1 hit.
PF08299. Bac_DnaA_C. 1 hit.
PF11638. DnaA_N. 1 hit.
[Graphical view]
PRINTSiPR00051. DNAA.
SMARTiSM00382. AAA. 1 hit.
SM00760. Bac_DnaA_C. 1 hit.
[Graphical view]
SUPFAMiSSF48295. SSF48295. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00362. DnaA. 1 hit.
PROSITEiPS01008. DNAA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDNAA_BACHK
AccessioniPrimary (citable) accession number: Q6HQ03
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: July 19, 2004
Last modified: November 2, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.