Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q6HPW7 (Q6HPW7_BACHK) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Ribose-phosphate pyrophosphokinase HAMAP-Rule MF_00583

Short name=RPPK HAMAP-Rule MF_00583
EC=2.7.6.1 HAMAP-Rule MF_00583
Alternative name(s):
Phosphoribosyl pyrophosphate synthase HAMAP-Rule MF_00583
Gene names
Name:prs HAMAP-Rule MF_00583 EMBL AAT59527.1
Ordered Locus Names:BT9727_0045 EMBL AAT59527.1
OrganismBacillus thuringiensis subsp. konkukian (strain 97-27) [Complete proteome] [HAMAP] EMBL AAT59527.1
Taxonomic identifier281309 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group

Protein attributes

Sequence length317 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP-Rule MF_00583 RuleBase RU004325

Cofactor

Binds 1 magnesium ion per subunit By similarity. HAMAP-Rule MF_00583

Pathway

Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1. HAMAP-Rule MF_00583

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00583.

Sequence similarities

Belongs to the ribose-phosphate pyrophosphokinase family. HAMAP-Rule MF_00583 RuleBase RU004324

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region217 – 230145-phosphoribose 1-diphosphate binding By similarity HAMAP-Rule MF_00583

Sites

Metal binding1341Magnesium By similarity HAMAP-Rule MF_00583
Metal binding1361Magnesium By similarity HAMAP-Rule MF_00583
Metal binding1451Magnesium By similarity HAMAP-Rule MF_00583
Metal binding1491Magnesium By similarity HAMAP-Rule MF_00583

Sequences

Sequence LengthMass (Da)Tools
Q6HPW7 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 16414CD5645DA23A

FASTA31734,836
        10         20         30         40         50         60 
MSTQYLNSNL KVFSLNSNKE LAEQIAKHIG VGLGKCSVDR FSDGEVQINI EESIRGCDVF 

        70         80         90        100        110        120 
IIQSTSFPVN EHIMELLIMI DALKRASAKT INIVIPYYGY ARQDRKARSR EPITSKLVAN 

       130        140        150        160        170        180 
LLETAGATRV ITLDLHAPQI QGFFDIPIDH LMGVPILSDY FETKGLKDIV IVSPDHGGVT 

       190        200        210        220        230        240 
RARKMADRLK APIAIIDKRR PRPNVSEVMN IIGNIEGKTA ILIDDIIDTA GTITLAANAL 

       250        260        270        280        290        300 
VENGASEVYA CCTHPVLSGP AIERIQNSNI KELVVTNSIV LPEEKKIDKV HELSVAPLIG 

       310 
EAIIRVYEEE SVSVLFN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017355 Genomic DNA. Translation: AAT59527.1.
RefSeqYP_034403.1. NC_005957.1.

3D structure databases

ProteinModelPortalQ6HPW7.
SMRQ6HPW7. Positions 2-316.
ModBaseSearch...

Protein-protein interaction databases

STRING281309.BT9727_0045.

Proteomic databases

PRIDEQ6HPW7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAT59527; AAT59527; BT9727_0045.
GeneID2856405.
KEGGbtk:BT9727_0045.
PATRIC18980429. VBIBacThu119411_0047.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000210451.
KOK00948.
OMAYVQIQES.
ProtClustDBPRK01259.

Enzyme and pathway databases

BioCycBTHU281309:GJID-54-MONOMER.
UniPathwayUPA00087; UER00172.

Family and domain databases

HAMAPMF_00583_B. RibP_PPkinase_B.
InterProIPR000842. PRib_PP_synth_CS.
IPR000836. PRibTrfase_dom.
IPR005946. Rib-P_diPkinase.
[Graphical view]
PfamPF00156. Pribosyltran. 1 hit.
[Graphical view]
TIGRFAMsTIGR01251. ribP_PPkin. 1 hit.
PROSITEPS00114. PRPP_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ6HPW7_BACHK
AccessionPrimary (citable) accession number: Q6HPW7
Entry history
Integrated into UniProtKB/TrEMBL: July 19, 2004
Last sequence update: July 19, 2004
Last modified: May 1, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)