Reviewed, UniProtKB/Swiss-Prot Q6HP49 (FENR1_BACHK)

Names and origin

Protein names

Recommended name:
    Ferredoxin--NADP reductase 1
      Short name=Fd-NADP+ reductase 1
      Short name=FNR 1
    EC=1.18.1.2

Gene names

Ordered Locus Names:

BT9727_0321

Organism

Bacillus thuringiensis subsp. konkukian [Complete proteome] [HAMAP]

Taxonomic identifier

180856 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	349 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685
Cofactor	Binds 1 FAD per subunit By similarity.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
Ligand	FAD Flavoprotein NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	FAD binding Inferred from electronic annotation. Source: HAMAP NADP or NADPH binding Inferred from electronic annotation. Source: HAMAP ferredoxin-NADP+ reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 349	349	Ferredoxin--NADP reductase 1 HAMAP MF_01685		PRO_0000364804
Sites
	Binding site	36	1	FAD By similarity
	Binding site	44	1	FAD By similarity
	Binding site	48	1	FAD By similarity
	Binding site	88	1	FAD; via amide nitrogen and carbonyl oxygen By similarity
	Binding site	123	1	FAD; via amide nitrogen By similarity
	Binding site	290	1	FAD By similarity
	Binding site	331	1	FAD By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6HP49-1 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: A6AE7F16F2AD131F	FASTA	349	38,690
	10 20 30 40 50 60 MNREELFDVT VIGGGPAGLY SAFYSGLREM KTKIIEFQPQ LGGKIHVYPE KMIWDIGGLL 70 80 90 100 110 120 PVTGEKLIEQ LVQQGLTFQP EVVLNTKIES IIRNKDGIFT LKTSTGEEHF SKTVIVATGS 130 140 150 160 170 180 GILNPQKLSI EGAERFEVSN LNYTVKSLKR FKNKTVIISG GGNSAIDWAN ELEPIAKKVY 190 200 210 220 230 240 LTYRKEELSG HEAQVKQLMN SSAECFFNTS ITTLIAGDNH EAIEYVELTN HETGEVSQLA 250 260 270 280 290 300 IDEVIINHGY ERDITLLENS ELDVAIIDNY YIAGNANSES SVDGLYAAGD ILKHEGKLHL 310 320 330 340 IAGAFQDAGN AVNKAKQFIQ PDASEYGMVS SHNEVFKKRN RELIKQMMK

References

[1]

"Pathogenomic sequence analysis of Bacillus cereus and Bacillus thuringiensis isolates closely related to Bacillus anthracis." Han C.S., Xie G., Challacombe J.F., Altherr M.R., Bhotika S.S., Bruce D., Campbell C.S., Campbell M.L., Chen J., Chertkov O., Cleland C., Dimitrijevic M., Doggett N.A., Fawcett J.J., Glavina T., Goodwin L.A., Hill K.K., Hitchcock P. , Jackson P.J., Keim P., Kewalramani A.R., Longmire J., Lucas S., Malfatti S., McMurry K., Meincke L.J., Misra M., Moseman B.L., Mundt M., Munk A.C., Okinaka R.T., Parson-Quintana B., Reilly L.P., Richardson P., Robinson D.L., Rubin E., Saunders E., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Ticknor L.O., Wills P.L., Brettin T.S., Gilna P. J. Bacteriol. 188:3382-3390(2006) [PubMed: 16621833] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 97-27.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017355 Genomic DNA. Translation: AAT58990.1.
RefSeq	YP_034671.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2858606.
GenomeReviews	Gene locus BT9727_0321 in contig AE017355_GR.
KEGG	btk:BT9727_0321.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q6HP49.
OMA	KKVYVTY.
Enzyme and pathway databases
BioCyc	BTHU281309:BT9727_0321-MON.
Family and domain databases
HAMAP	MF_01685. [Tree]
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR001327. Pyr_OxRdtase_NAD_bd. IPR000103. Pyridine_nuc-diS_OxRdtase_2. [Graphical view]
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
ProDom	PD000139. FAD_pyr_redox. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

FENR1_BACHK

Accession

Primary (citable) accession number: Q6HP49

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	July 19, 2004
Last modified:	November 3, 2009
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)