Q6HP15 (Y355_BACHK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable methyl-accepting chemotaxis protein BT9727_0355

Gene names

Ordered Locus Names:

BT9727_0355

Organism

Bacillus thuringiensis subsp. konkukian (strain 97-27) [Complete proteome] [HAMAP]

Taxonomic identifier

281309 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group › Bacillus thuringiensis › Bacillus thuringiensis subsp. konkukian

Protein attributes

Sequence length	579 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation By similarity.
Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Sequence similarities	Contains 1 HAMP domain. Contains 1 methyl-accepting transducer domain.

Ontologies

Keywords
Biological process	Chemotaxis
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Molecular function	Transducer
PTM	Methylation
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	chemotaxis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	signal transducer activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 579	579	Probable methyl-accepting chemotaxis protein BT9727_0355		PRO_0000394196
Regions
	Topological domain	1 – 13	13	Cytoplasmic Potential
	Transmembrane	14 – 34	21	Helical; Potential
	Topological domain	35 – 198	164	Extracellular Potential
	Transmembrane	199 – 219	21	Helical; Potential
	Topological domain	220 – 579	360	Cytoplasmic Potential
	Domain	223 – 274	52	HAMP
	Domain	293 – 529	237	Methyl-accepting transducer
Amino acid modifications
	Modified residue	289	1	Glutamate methyl ester (Glu) By similarity
	Modified residue	548	1	Glutamate methyl ester (Glu) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6HP15 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: 3E756CA69DBABBC7	FASTA	579	64,172
	10 20 30 40 50 60 MKKYWHKLSF LQKNVLLTVL VILTLVGTMG ALSFNMFQNS MMSIFERHSF ETGDTVLHKL 70 80 90 100 110 120 DEEIVRDVTK DPVAQREKRE KLTEKLDEAT EELNSVGQTY IVGAKKNEKG ELLIVDLSTD 130 140 150 160 170 180 LANVVEVRPG EYYKQPDLWM EAYDKVMSTK KANMTVVYED LLGTWVTILE PIKDGEGNIV 190 200 210 220 230 240 AIVAADVDAS IVPSTKEKFI IQGLMFICIS VLIATVIQFL IVRNALAPLR DLREGLRRVG 250 260 270 280 290 300 EGDLNIKLEE RSDDIGIINS YFNNTIEKFK GIIDKVKQTA EQVSSSSQEL SVSTKENSMA 310 320 330 340 350 360 VQEIVSSMVE LRAGAQLQET SVPQYLGIVY EVEDKMEEIT NAAKQMEKVS EGIEHHSVKG 370 380 390 400 410 420 NGVTKQAINQ MNIIQNAVQD LSSIIYSLEV RSKEISDIVT VITSISNQTN SLALHATIEA 430 440 450 460 470 480 SRAEETGEGF AVVADEVRKL AEQMEASAKD IANLIGETQA GTEEAVVSIR KASKEVESGM 490 500 510 520 530 540 KLVEMNGAFF EEISKSAQSV TNQVRVVSSN SSDILQNSQN IVRVVNELSL IANTYTNSSS 550 560 570 NVEESMKEQE MSVQDIAELA SSLSWLSQEL QELIGEFKS

References

[1]

"Pathogenomic sequence analysis of Bacillus cereus and Bacillus thuringiensis isolates closely related to Bacillus anthracis." Han C.S., Xie G., Challacombe J.F., Altherr M.R., Bhotika S.S., Bruce D., Campbell C.S., Campbell M.L., Chen J., Chertkov O., Cleland C., Dimitrijevic M., Doggett N.A., Fawcett J.J., Glavina T., Goodwin L.A., Hill K.K., Hitchcock P. , Jackson P.J., Keim P., Kewalramani A.R., Longmire J., Lucas S., Malfatti S., McMurry K., Meincke L.J., Misra M., Moseman B.L., Mundt M., Munk A.C., Okinaka R.T., Parson-Quintana B., Reilly L.P., Richardson P., Robinson D.L., Rubin E., Saunders E., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Ticknor L.O., Wills P.L., Brettin T.S., Gilna P. J. Bacteriol. 188:3382-3390(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 97-27.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017355 Genomic DNA. Translation: AAT61241.1.
RefSeq	YP_034705.1. NC_005957.1.
3D structure databases
ProteinModelPortal	Q6HP15.
ModBase	Search...
Protein-protein interaction databases
STRING	281309.BT9727_0355.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAT61241; AAT61241; BT9727_0355.
GeneID	2855698.
KEGG	btk:BT9727_0355.
PATRIC	18981207. VBIBacThu119411_0377.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0840.
HOGENOM	HOG000082867.
KO	K03406.
OMA	SHIANMY.
ProtClustDB	CLSK915803.
Enzyme and pathway databases
BioCyc	BTHU281309:GJID-415-MONOMER.
Family and domain databases
InterPro	IPR004090. Chemotax_Me-accpt_rcpt. IPR003660. HAMP_linker_domain. IPR004089. MCPsignal_dom. [Graphical view]
Pfam	PF00672. HAMP. 1 hit. PF00015. MCPsignal. 1 hit. [Graphical view]
PRINTS	PR00260. CHEMTRNSDUCR.
SMART	SM00304. HAMP. 3 hits. SM00283. MA. 1 hit. [Graphical view]
PROSITE	PS00538. CHEMOTAXIS_TRANSDUC_1. False negative. PS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit. PS50885. HAMP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y355_BACHK

Accession

Primary (citable) accession number: Q6HP15

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 18, 2010
Last sequence update:	July 19, 2004
Last modified:	May 1, 2013
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program