Q6HNQ4 (Y469_BACHK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable methyl-accepting chemotaxis protein BT9727_0469

Gene names

Ordered Locus Names:

BT9727_0469

Organism

Bacillus thuringiensis subsp. konkukian (strain 97-27) [Complete proteome] [HAMAP]

Taxonomic identifier

281309 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group › Bacillus thuringiensis › Bacillus thuringiensis subsp. konkukian

Protein attributes

Sequence length	658 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation By similarity.
Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Sequence similarities	Contains 1 cache domain. Contains 1 HAMP domain. Contains 1 methyl-accepting transducer domain.

Ontologies

Keywords
Biological process	Chemotaxis
Cellular component	Cell membrane Membrane
Domain	Coiled coil Transmembrane Transmembrane helix
Molecular function	Transducer
PTM	Methylation
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	chemotaxis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	transmembrane signaling receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 658	658	Probable methyl-accepting chemotaxis protein BT9727_0469		PRO_0000394197
Regions
	Topological domain	1 – 14	14	Cytoplasmic Potential
	Transmembrane	15 – 35	21	Helical; Potential
	Topological domain	36 – 283	248	Extracellular Potential
	Transmembrane	284 – 304	21	Helical; Potential
	Topological domain	305 – 658	354	Cytoplasmic Potential
	Domain	150 – 221	72	Cache
	Domain	301 – 353	53	HAMP
	Domain	372 – 622	251	Methyl-accepting transducer
	Coiled coil	44 – 109	66	Potential
Amino acid modifications
	Modified residue	368	1	Glutamate methyl ester (Glu) By similarity
	Modified residue	592	1	Deamidated glutamine By similarity
	Modified residue	592	1	Glutamate methyl ester (Gln) By similarity
	Modified residue	627	1	Glutamate methyl ester (Glu) By similarity
	Modified residue	634	1	Glutamate methyl ester (Glu) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6HNQ4 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: A22A970CBB20F847	FASTA	658	71,649
	10 20 30 40 50 60 MLQGKLRRSS LKAKLLVSFV IVLILPSIVI GWTSYQQAKT NFNETILQSA EDNVKILNNV 70 80 90 100 110 120 INKEIDSKKV DAVYFTKLFN GVSYGTDQLQ NVQNKLEEYN KLHPEIEAIY TGSSTGQFIQ 130 140 150 160 170 180 SPSIQMPDGY NPTERDWYKE AAKKSGEVVI TAPYKSSTTG NIVITIAKQN EDKSGVLGID 190 200 210 220 230 240 LIINDIVNTS KMVNIGKTGF VAIFDQSKHV IAHPTMKPGD KIEEKVEKEL YKQETGDFKF 250 260 270 280 290 300 KLDGDDRNIT FITNKQTGWK IAGIMPSKEI IEAANPIFYK TLTVIGISLI IGGVLIYFII 310 320 330 340 350 360 ASIISPLKQL VISSKKISEG DLTETITVHS KDEIGQLGES FNEMAASLHH VISNINTSAS 370 380 390 400 410 420 HVAASSEELT ASMKQTSEAT EQITQAIEQV SSGAEIQTKE VEEGATLLEG VTEGIQRVAD 430 440 450 460 470 480 SSSLVSTASM YTKKKAEDGG KLVEQTVNQM QLIHESVSQS DKVIVLLDDK SKQIGAILEV 490 500 510 520 530 540 IQHIAEQTNL LALNAAIEAA RAGEQGRGFA IVADEVRKLA EQSGQSSTEI GKLVKEIQFD 550 560 570 580 590 600 IKETVSSMKQ VGTEVQSGLV VANETKQSFA EILKSTDDTV VQIDNMVDVA KQMTVDARQV 610 620 630 640 650 SASINEIAAT IEENAASVQN IAGSSEEQLA SVDEINAAAV HLSQMAEELQ EMIGKFKV

References

[1]

"Pathogenomic sequence analysis of Bacillus cereus and Bacillus thuringiensis isolates closely related to Bacillus anthracis." Han C.S., Xie G., Challacombe J.F., Altherr M.R., Bhotika S.S., Bruce D., Campbell C.S., Campbell M.L., Chen J., Chertkov O., Cleland C., Dimitrijevic M., Doggett N.A., Fawcett J.J., Glavina T., Goodwin L.A., Hill K.K., Hitchcock P. , Jackson P.J., Keim P., Kewalramani A.R., Longmire J., Lucas S., Malfatti S., McMurry K., Meincke L.J., Misra M., Moseman B.L., Mundt M., Munk A.C., Okinaka R.T., Parson-Quintana B., Reilly L.P., Richardson P., Robinson D.L., Rubin E., Saunders E., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Ticknor L.O., Wills P.L., Brettin T.S., Gilna P. J. Bacteriol. 188:3382-3390(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 97-27.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017355 Genomic DNA. Translation: AAT62354.1.
RefSeq	YP_034817.1. NC_005957.1.
3D structure databases
ProteinModelPortal	Q6HNQ4.
ModBase	Search...
Protein-protein interaction databases
STRING	281309.BT9727_0469.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAT62354; AAT62354; BT9727_0469.
GeneID	2856487.
KEGG	btk:BT9727_0469.
PATRIC	18981489. VBIBacThu119411_0499.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0840.
HOGENOM	HOG000083278.
KO	K03406.
OMA	RIEDIQH.
ProtClustDB	CLSK887785.
Enzyme and pathway databases
BioCyc	BTHU281309:GJID-546-MONOMER.
Family and domain databases
InterPro	IPR004010. Cache_domain. IPR003122. Chemotax_Me-accpt_rcpt_lig-bd. IPR003660. HAMP_linker_domain. IPR004089. MCPsignal_dom. [Graphical view]
Pfam	PF02743. Cache_1. 1 hit. PF00672. HAMP. 1 hit. PF00015. MCPsignal. 1 hit. PF02203. TarH. 1 hit. [Graphical view]
SMART	SM00304. HAMP. 2 hits. SM00283. MA. 1 hit. [Graphical view]
PROSITE	PS00538. CHEMOTAXIS_TRANSDUC_1. False negative. PS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit. PS50885. HAMP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y469_BACHK

Accession

Primary (citable) accession number: Q6HNQ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 18, 2010
Last sequence update:	July 19, 2004
Last modified:	May 1, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program