Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q6HLY2 (PPNK1_BACHK) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable inorganic polyphosphate/ATP-NAD kinase 1

Short name=Poly(P)/ATP NAD kinase 1
EC=2.7.1.23
Gene names
Name:ppnK1
Ordered Locus Names:BT9727_1102
OrganismBacillus thuringiensis subsp. konkukian (strain 97-27) [Complete proteome] [HAMAP]
Taxonomic identifier281309 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacillalesBacillaceaeBacillusBacillus cereus group

Protein attributes

Sequence length265 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP MF_00361

Catalytic activity

ATP + NAD+ = ADP + NADP+. HAMAP MF_00361

Cofactor

Divalent metal ions By similarity. HAMAP MF_00361

Subcellular location

Cytoplasm By similarity HAMAP MF_00361.

Sequence similarities

Belongs to the NAD kinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
NAD
NADP
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

NAD+ kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 265265Probable inorganic polyphosphate/ATP-NAD kinase 1 HAMAP MF_00361
PRO_0000229606

Sequences

Sequence LengthMass (Da)Tools
Q6HLY2 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 1ABE86E26E84AB94

FASTA26529,828
        10         20         30         40         50         60 
MKFTIMSKGD QSSDTLASTM KEYLLDFGFI MDEQEPDIVI SVGGDGTLLY AFHRYYNRLD 

        70         80         90        100        110        120 
ETAFVGVHTG HLGFYADWLP TEVEKLVIAI AKTPFQVVEY PLLEVIIRYM NGSKESQYLA 

       130        140        150        160        170        180 
MNEATVKSAE GTLVTEVEIR GEYFETFRGD GLCISTPSGS TAYNKALGGA IIHPSIEAIQ 

       190        200        210        220        230        240 
IAEMASINNR VFRTVGSPLV LPKHHTCVLK PTAGMNLQIT VDHLTMVHQD VKSIQYRVAN 

       250        260 
EKVRFVRFRP FPFWKRVRDS FVADK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017355 Genomic DNA. Translation: AAT59333.1.
RefSeqYP_035439.1. NC_005957.1.

3D structure databases

ProteinModelPortalQ6HLY2.
SMRQ6HLY2. Positions 1-262.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000072920; EBBACP00000071006; EBBACG00000072911.
GeneID2858516.
GenomeReviewsGene locus BT9727_1102 in contig AE017355_GR.
KEGGbtk:BT9727_1102.
PATRIC18982861. VBIBacThu119411_1161.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000002705.
HOGENOMHBG314020.
OMATISFANC.
ProtClustDBPRK04885.

Enzyme and pathway databases

BioCycBTHU281309:BT9727_1102-MONOMER.

Family and domain databases

HAMAPMF_00361. NAD_kinase.
[Tree]
InterProIPR016064. ATP-NAD_kinase_PpnK-typ.
IPR017438. ATP-NAD_kinase_PpnK-typ_a/b.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. polyP/ATP_NADK_prd.
[Graphical view]
Gene3DG3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit.
G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 1 hit.
KOK00858.
PANTHERPTHR20275. ATP_NADK. 1 hit.
PfamPF01513. NAD_kinase. 1 hit.
[Graphical view]
SUPFAMSSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNetSearch...

Entry information

Entry namePPNK1_BACHK
AccessionPrimary (citable) accession number: Q6HLY2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: July 19, 2004
Last modified: January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families