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Q6HLG8 (UPPP3_BACHK) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase 3

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein 3
Undecaprenyl pyrophosphate phosphatase 3
Gene names
Name:uppP3
Synonyms:bacA
Ordered Locus Names:BT9727_1268
OrganismBacillus thuringiensis subsp. konkukian (strain 97-27) [Complete proteome] [HAMAP]
Taxonomic identifier281309 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group

Protein attributes

Sequence length263 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 263263Undecaprenyl-diphosphatase 3 HAMAP-Rule MF_01006
PRO_0000151103

Regions

Transmembrane15 – 3723Helical; Potential
Transmembrane42 – 6221Helical; Potential
Transmembrane83 – 10321Helical; Potential
Transmembrane106 – 12621Helical; Potential
Transmembrane142 – 16221Helical; Potential
Transmembrane183 – 20321Helical; Potential
Transmembrane216 – 23621Helical; Potential
Transmembrane242 – 26221Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q6HLG8 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 12006A7D5878D559

FASTA26328,394
        10         20         30         40         50         60 
MADWLIGIIM GAVEGLTEFL PVSSTGHMIL TGHLIGFDDD RAKVFEVVIQ LGSILAVVVI 

        70         80         90        100        110        120 
FWKRLWSLVG IGKVTDGPSL NLLHIIIGMI PAGVLGVLFH SAIKEVLFGP GPVVISLVAG 

       130        140        150        160        170        180 
GILMIVAEKF SKPSTARTLD EITYKQAFTI GMFQCLALWP GFSRSGSTIS GGLLARVSHT 

       190        200        210        220        230        240 
AAAEYTFILA VPMMVAASGL DLIKSWDILS TADIQLFATG FITAFVVAML AIVSFLKLLS 

       250        260 
RVKLTPFAYY RFILAAVFYF FIM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017355 Genomic DNA. Translation: AAT61949.1.
RefSeqYP_035603.1. NC_005957.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING281309.BT9727_1268.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAT61949; AAT61949; BT9727_1268.
GeneID2856634.
KEGGbtk:BT9727_1268.
PATRIC18983213. VBIBacThu119411_1336.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMALMIYMEN.
OrthoDBEOG6QP13M.
ProtClustDBPRK00281.

Enzyme and pathway databases

BioCycBTHU281309:GJID-1357-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP3_BACHK
AccessionPrimary (citable) accession number: Q6HLG8
Entry history
Integrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: July 19, 2004
Last modified: February 19, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families