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Q6HLD4 (CYSH_BACHK) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoadenosine phosphosulfate reductase

EC=1.8.4.8
Alternative name(s):
3'-phosphoadenylylsulfate reductase
PAPS reductase, thioredoxin dependent
PAPS sulfotransferase
PAdoPS reductase
Gene names
Name:cysH
Ordered Locus Names:BT9727_1303
OrganismBacillus thuringiensis subsp. konkukian (strain 97-27) [Complete proteome] [HAMAP]
Taxonomic identifier281309 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacillalesBacillaceaeBacillusBacillus cereus group

Protein attributes

Sequence length234 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Reduction of activated sulfate into sulfite. HAMAP MF_00063

Catalytic activity

Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin. HAMAP MF_00063

Pathway

Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3. HAMAP MF_00063

Subcellular location

Cytoplasm By similarity HAMAP MF_00063.

Sequence similarities

Belongs to the PAPS reductase family. CysH subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 234234Phosphoadenosine phosphosulfate reductase HAMAP MF_00063
PRO_1000008918

Sequences

Sequence LengthMass (Da)Tools
Q6HLD4 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 129C2C6F894345DE

FASTA23427,331
        10         20         30         40         50         60 
MLTYETWEEN DISFSEEDET KGALSVLSWA YKEYENEIVY ACSFGVEGMV LLHLINQVNP 

        70         80         90        100        110        120 
SAKVVFLDTN VHFQETYELI QKVRERFPSL NIIEKQPKLT LDEQAKLHGN KLWESNPNLC 

       130        140        150        160        170        180 
CKIRKILPLE ESLANEKAWI SGLRREQSET RKHTKFINQD HRFQSIKVCP LIHWTWKEVW 

       190        200        210        220        230 
RYVYKHSLPY NPLHDIGYPS IGCEKCTLPV GEGGDSRDGR WAGKVKTECG LHYQ 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017355 Genomic DNA. Translation: AAT59429.1.
RefSeqYP_035637.1. NC_005957.1.

3D structure databases

HSSPHSSP built from PDB template 1SUR based on UniProtKB P17854.
ProteinModelPortalQ6HLD4.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000071665; EBBACP00000069751; EBBACG00000071656.
GeneID2855488.
GenomeReviewsGene locus BT9727_1303 in contig AE017355_GR.
KEGGbtk:BT9727_1303.
NMPDRfig|281309.1.peg.1277.
PATRIC18983289. VBIBacThu119411_1374.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000002870.
HOGENOMHBG758022.
OMAAIHGTRF.
ProtClustDBCLSK916236.

Enzyme and pathway databases

BioCycBTHU281309:BT9727_1303-MONOMER.

Family and domain databases

HAMAPMF_00063. CysH.
[Tree]
InterProIPR011798. APS_reductase.
IPR004511. PAPS/APS_Rdtase.
IPR002500. PAPS_reduct.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
Gene3DG3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
KOK00390.
PfamPF01507. PAPS_reduct. 1 hit.
[Graphical view]
PIRSFPIRSF000857. PAPS_reductase. 1 hit.
TIGRFAMsTIGR02055. APS_reductase. 1 hit.
TIGR00434. CysH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCYSH_BACHK
AccessionPrimary (citable) accession number: Q6HLD4
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 19, 2004
Last modified: January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families