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Q6HKA6 (Q6HKA6_BACHK) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401
Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP MF_01401
Gene names
Name:msrB EMBL AAT63316.1
Synonyms:msrA HAMAP MF_01401
Ordered Locus Names:BT9727_1688
OrganismBacillus thuringiensis subsp. konkukian (strain 97-27) [Complete proteome] [HAMAP]
Taxonomic identifier281309 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length178 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401

Catalytic activity

L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
   Molecular functionOxidoreductase HAMAP MF_01401 EMBL AAT63316.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processprotein modification process

Inferred from electronic annotation. Source: HAMAP

   Molecular functionpeptide-methionine-(S)-S-oxide reductase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site151 By similarity HAMAP MF_01401

Sequences

Sequence LengthMass (Da)Tools
Q6HKA6 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 4D49CB1DDAE7C521

FASTA17820,608
        10         20         30         40         50         60 
MSEKTYELAT FAGGCFWCMV KPFDELPGIH KVLSGYAGGH VENPTYEQVK AGTSGHLEVV 

        70         80         90        100        110        120 
QITFDPSIFP YEKLLNLYWP QIDPTDDGGQ FFDRGPSYRT AIFYHNEMQK ELAEKSKQTL 

       130        140        150        160        170 
AESGMFKDPI VTEIRPAAPF YEAEEYHQHF YKKNPEKYAT EQKESGREDF IKENWQKK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017355 Genomic DNA. Translation: AAT63316.1.
RefSeqYP_036020.1. NC_005957.1.

3D structure databases

ProteinModelPortalQ6HKA6.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000071548; EBBACP00000069634; EBBACG00000071539.
GeneID2857658.
GenomeReviewsGene locus BT9727_1688 in contig AE017355_GR.
KEGGbtk:BT9727_1688.
NMPDRfig|281309.1.peg.1660.
PATRIC18984098. VBIBacThu119411_1778.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000000580.
HOGENOMHBG748152.
OMALVELYWT.
ProtClustDBCLSK916383.

Family and domain databases

HAMAPMF_01401. MsrA.
[Tree]
InterProIPR002569. Peptide_Met_Sox_Rdtase_MsrA.
[Graphical view]
Gene3DG3DSA:3.30.1060.10. MsrA. 1 hit.
KOK07304.
PfamPF01625. PMSR. 1 hit.
[Graphical view]
SUPFAMSSF55068. MsrA. 1 hit.
TIGRFAMsTIGR00401. MsrA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ6HKA6_BACHK
AccessionPrimary (citable) accession number: Q6HKA6
Entry history
Integrated into UniProtKB/TrEMBL: July 19, 2004
Last sequence update: July 19, 2004
Last modified: January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info