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Q6HHX8

- KYNB_BACHK

UniProt

Q6HHX8 - KYNB_BACHK

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Protein
Kynurenine formamidase
Gene
kynB, BT9727_2522
Organism
Bacillus thuringiensis subsp. konkukian (strain 97-27)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation By similarity.UniRule annotation

Catalytic activityi

N-formyl-L-kynurenine + H2O = formate + L-kynurenine.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. arylformamidase activity Source: UniProtKB
  2. formamidase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. anthranilate metabolic process Source: UniProtKB
  2. tryptophan catabolic process to kynurenine Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Tryptophan catabolism

Enzyme and pathway databases

BioCyciBTHU281309:GJID-2602-MONOMER.
UniPathwayiUPA00333; UER00454.

Names & Taxonomyi

Protein namesi
Recommended name:
Kynurenine formamidase (EC:3.5.1.9)
Short name:
KFA
Short name:
KFase
Alternative name(s):
Arylformamidase
N-formylkynurenine formamidase
Short name:
FKF
Gene namesi
Name:kynB
Ordered Locus Names:BT9727_2522
OrganismiBacillus thuringiensis subsp. konkukian (strain 97-27)
Taxonomic identifieri281309 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000001301: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 209209Kynurenine formamidaseUniRule annotation
PRO_0000362093Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi281309.BT9727_2522.

Structurei

3D structure databases

ProteinModelPortaliQ6HHX8.

Family & Domainsi

Sequence similaritiesi

Belongs to the KynB family.

Phylogenomic databases

eggNOGiCOG1878.
HOGENOMiHOG000219455.
KOiK07130.
OMAiYEARKFI.
OrthoDBiEOG67T5JJ.

Family and domain databases

HAMAPiMF_01969. KynB.
InterProiIPR007325. KFase.
IPR017484. Kynurenine_formamidase_bac.
[Graphical view]
PfamiPF04199. Cyclase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03035. trp_arylform. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6HHX8-1 [UniParc]FASTAAdd to Basket

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MKTSEWIDIS QPLNNDIATW PGDTPFSYEV SWSKEESGSV NVGKLTMSIH    50
TGTHIDAPFH FDNNGKKVLD LDIQVYVGPT RIIDVSNLES IGKKELEKFH 100
LEGVERLLLR TSSHGKANEF PDIIPHLRAD IAPFLSEKGI RLIGVDVPSV 150
DPLDDKELAA HHQLFKHGIH ILENVVLDHV ADGDYELIAL PLALSDADGS 200
PVRAVIKPI 209
Length:209
Mass (Da):23,104
Last modified:July 19, 2004 - v1
Checksum:i757CC1F2F68A0975
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017355 Genomic DNA. Translation: AAT61841.1.
RefSeqiYP_036848.1. NC_005957.1.

Genome annotation databases

EnsemblBacteriaiAAT61841; AAT61841; BT9727_2522.
GeneIDi2857285.
KEGGibtk:BT9727_2522.
PATRICi18985887. VBIBacThu119411_2670.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017355 Genomic DNA. Translation: AAT61841.1 .
RefSeqi YP_036848.1. NC_005957.1.

3D structure databases

ProteinModelPortali Q6HHX8.
ModBasei Search...

Protein-protein interaction databases

STRINGi 281309.BT9727_2522.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAT61841 ; AAT61841 ; BT9727_2522 .
GeneIDi 2857285.
KEGGi btk:BT9727_2522.
PATRICi 18985887. VBIBacThu119411_2670.

Phylogenomic databases

eggNOGi COG1878.
HOGENOMi HOG000219455.
KOi K07130.
OMAi YEARKFI.
OrthoDBi EOG67T5JJ.

Enzyme and pathway databases

UniPathwayi UPA00333 ; UER00454 .
BioCyci BTHU281309:GJID-2602-MONOMER.

Family and domain databases

HAMAPi MF_01969. KynB.
InterProi IPR007325. KFase.
IPR017484. Kynurenine_formamidase_bac.
[Graphical view ]
Pfami PF04199. Cyclase. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR03035. trp_arylform. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 97-27.

Entry informationi

Entry nameiKYNB_BACHK
AccessioniPrimary (citable) accession number: Q6HHX8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: July 19, 2004
Last modified: September 3, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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