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Q6HHX8

- KYNB_BACHK

UniProt

Q6HHX8 - KYNB_BACHK

Protein

Kynurenine formamidase

Gene

kynB

Organism
Bacillus thuringiensis subsp. konkukian (strain 97-27)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 1 (19 Jul 2004)
      Previous versions | rss
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    Functioni

    Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.UniRule annotation

    Catalytic activityi

    N-formyl-L-kynurenine + H2O = formate + L-kynurenine.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. arylformamidase activity Source: UniProtKB
    2. formamidase activity Source: InterPro

    GO - Biological processi

    1. anthranilate metabolic process Source: UniProtKB
    2. tryptophan catabolic process to kynurenine Source: UniProtKB

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Tryptophan catabolism

    Enzyme and pathway databases

    BioCyciBTHU281309:GJID-2602-MONOMER.
    UniPathwayiUPA00333; UER00454.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Kynurenine formamidaseUniRule annotation (EC:3.5.1.9UniRule annotation)
    Short name:
    KFAUniRule annotation
    Short name:
    KFaseUniRule annotation
    Alternative name(s):
    ArylformamidaseUniRule annotation
    N-formylkynurenine formamidaseUniRule annotation
    Short name:
    FKFUniRule annotation
    Gene namesi
    Name:kynBUniRule annotation
    Ordered Locus Names:BT9727_2522
    OrganismiBacillus thuringiensis subsp. konkukian (strain 97-27)
    Taxonomic identifieri281309 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
    ProteomesiUP000001301: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 209209Kynurenine formamidasePRO_0000362093Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi281309.BT9727_2522.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6HHX8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the KynB family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1878.
    HOGENOMiHOG000219455.
    KOiK07130.
    OMAiYEARKFI.
    OrthoDBiEOG67T5JJ.

    Family and domain databases

    HAMAPiMF_01969. KynB.
    InterProiIPR007325. KFase.
    IPR017484. Kynurenine_formamidase_bac.
    [Graphical view]
    PfamiPF04199. Cyclase. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR03035. trp_arylform. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q6HHX8-1 [UniParc]FASTAAdd to Basket

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    MKTSEWIDIS QPLNNDIATW PGDTPFSYEV SWSKEESGSV NVGKLTMSIH    50
    TGTHIDAPFH FDNNGKKVLD LDIQVYVGPT RIIDVSNLES IGKKELEKFH 100
    LEGVERLLLR TSSHGKANEF PDIIPHLRAD IAPFLSEKGI RLIGVDVPSV 150
    DPLDDKELAA HHQLFKHGIH ILENVVLDHV ADGDYELIAL PLALSDADGS 200
    PVRAVIKPI 209
    Length:209
    Mass (Da):23,104
    Last modified:July 19, 2004 - v1
    Checksum:i757CC1F2F68A0975
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017355 Genomic DNA. Translation: AAT61841.1.
    RefSeqiYP_036848.1. NC_005957.1.

    Genome annotation databases

    EnsemblBacteriaiAAT61841; AAT61841; BT9727_2522.
    GeneIDi2857285.
    KEGGibtk:BT9727_2522.
    PATRICi18985887. VBIBacThu119411_2670.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017355 Genomic DNA. Translation: AAT61841.1 .
    RefSeqi YP_036848.1. NC_005957.1.

    3D structure databases

    ProteinModelPortali Q6HHX8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 281309.BT9727_2522.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAT61841 ; AAT61841 ; BT9727_2522 .
    GeneIDi 2857285.
    KEGGi btk:BT9727_2522.
    PATRICi 18985887. VBIBacThu119411_2670.

    Phylogenomic databases

    eggNOGi COG1878.
    HOGENOMi HOG000219455.
    KOi K07130.
    OMAi YEARKFI.
    OrthoDBi EOG67T5JJ.

    Enzyme and pathway databases

    UniPathwayi UPA00333 ; UER00454 .
    BioCyci BTHU281309:GJID-2602-MONOMER.

    Family and domain databases

    HAMAPi MF_01969. KynB.
    InterProi IPR007325. KFase.
    IPR017484. Kynurenine_formamidase_bac.
    [Graphical view ]
    Pfami PF04199. Cyclase. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR03035. trp_arylform. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 97-27.

    Entry informationi

    Entry nameiKYNB_BACHK
    AccessioniPrimary (citable) accession number: Q6HHX8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 10, 2009
    Last sequence update: July 19, 2004
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3