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Q6HHF8

- AROA_BACHK

UniProt

Q6HHF8 - AROA_BACHK

Protein

3-phosphoshikimate 1-carboxyvinyltransferase

Gene

aroA

Organism
Bacillus thuringiensis subsp. konkukian (strain 97-27)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (19 Jul 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. 3-phosphoshikimate 1-carboxyvinyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. aromatic amino acid family biosynthetic process Source: UniProtKB-KW
    2. chorismate biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis

    Enzyme and pathway databases

    BioCyciBTHU281309:GJID-2772-MONOMER.
    UniPathwayiUPA00053; UER00089.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    3-phosphoshikimate 1-carboxyvinyltransferaseUniRule annotation (EC:2.5.1.19UniRule annotation)
    Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate synthaseUniRule annotation
    Short name:
    EPSP synthaseUniRule annotation
    Short name:
    EPSPSUniRule annotation
    Gene namesi
    Name:aroAUniRule annotation
    Ordered Locus Names:BT9727_2694
    OrganismiBacillus thuringiensis subsp. konkukian (strain 97-27)
    Taxonomic identifieri281309 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
    ProteomesiUP000001301: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 4294293-phosphoshikimate 1-carboxyvinyltransferasePRO_0000088224Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi281309.BT9727_2694.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6HHF8.
    SMRiQ6HHF8. Positions 6-428.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the EPSP synthase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0128.
    HOGENOMiHOG000247371.
    KOiK00800.
    OMAiGEDCLAT.
    OrthoDBiEOG6Z6FZ4.

    Family and domain databases

    Gene3Di3.65.10.10. 2 hits.
    HAMAPiMF_00210. EPSP_synth.
    InterProiIPR001986. Enolpyruvate_Tfrase_dom.
    IPR006264. EPSP_synthase.
    IPR023193. EPSP_synthase_CS.
    IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
    [Graphical view]
    PfamiPF00275. EPSP_synthase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000505. EPSPS. 1 hit.
    SUPFAMiSSF55205. SSF55205. 1 hit.
    TIGRFAMsiTIGR01356. aroA. 1 hit.
    PROSITEiPS00104. EPSP_SYNTHASE_1. 1 hit.
    PS00885. EPSP_SYNTHASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6HHF8-1 [UniParc]FASTAAdd to Basket

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    MKERTIQPVN NGLNGNITIP GDKSISHRAV MFGAIAEGTT TIKGFLPGAD    50
    CLSTISCFKE MGVDIVQDGD EVTVVGKGLE GLQEPKAVLD VGNSGTTIRL 100
    MSGILANTPF FSCVQGDASI AKRPMKRVTN PLKQMGANID GREEGTFTPL 150
    TVRGGDLKAI EYTSPVASAQ VKSAILLAGL RAEGVTAVTE PHISRDHTER 200
    MLEAFGVKVT REGKTVKLAG GQKLTATDVQ VPGDVSSAAF FLVAGAIIPN 250
    SKLVLENVGM NPTRTGIIDV LEKMGATFTV EPINEGASEP AANITIETSS 300
    LKGIEIGGDI IPRLIDEIPV IALAATQAEG ITVIKDAHEL KVKETNRIDT 350
    VVAELTKLGA RIEATDDGMI IYGKSALKGN TVNSYGDHRI GMMLAIAGCI 400
    AEGKTIIEDA EAVGVSYPTF FEELQKLAK 429
    Length:429
    Mass (Da):45,156
    Last modified:July 19, 2004 - v1
    Checksum:iD8B3CC699D0DE108
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017355 Genomic DNA. Translation: AAT61256.1.
    RefSeqiWP_000664618.1. NC_005957.1.
    YP_037018.1. NC_005957.1.

    Genome annotation databases

    EnsemblBacteriaiAAT61256; AAT61256; BT9727_2694.
    GeneIDi2853981.
    KEGGibtk:BT9727_2694.
    PATRICi18986267. VBIBacThu119411_2860.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017355 Genomic DNA. Translation: AAT61256.1 .
    RefSeqi WP_000664618.1. NC_005957.1.
    YP_037018.1. NC_005957.1.

    3D structure databases

    ProteinModelPortali Q6HHF8.
    SMRi Q6HHF8. Positions 6-428.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 281309.BT9727_2694.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAT61256 ; AAT61256 ; BT9727_2694 .
    GeneIDi 2853981.
    KEGGi btk:BT9727_2694.
    PATRICi 18986267. VBIBacThu119411_2860.

    Phylogenomic databases

    eggNOGi COG0128.
    HOGENOMi HOG000247371.
    KOi K00800.
    OMAi GEDCLAT.
    OrthoDBi EOG6Z6FZ4.

    Enzyme and pathway databases

    UniPathwayi UPA00053 ; UER00089 .
    BioCyci BTHU281309:GJID-2772-MONOMER.

    Family and domain databases

    Gene3Di 3.65.10.10. 2 hits.
    HAMAPi MF_00210. EPSP_synth.
    InterProi IPR001986. Enolpyruvate_Tfrase_dom.
    IPR006264. EPSP_synthase.
    IPR023193. EPSP_synthase_CS.
    IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
    [Graphical view ]
    Pfami PF00275. EPSP_synthase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000505. EPSPS. 1 hit.
    SUPFAMi SSF55205. SSF55205. 1 hit.
    TIGRFAMsi TIGR01356. aroA. 1 hit.
    PROSITEi PS00104. EPSP_SYNTHASE_1. 1 hit.
    PS00885. EPSP_SYNTHASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 97-27.

    Entry informationi

    Entry nameiAROA_BACHK
    AccessioniPrimary (citable) accession number: Q6HHF8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 15, 2005
    Last sequence update: July 19, 2004
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3