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Q6HHF8 (AROA_BACHK) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase

EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:BT9727_2694
OrganismBacillus thuringiensis subsp. konkukian (strain 97-27) [Complete proteome] [HAMAP]
Taxonomic identifier281309 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group

Protein attributes

Sequence length429 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP-Rule MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP-Rule MF_00210

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00210

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

chorismate biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4294293-phosphoshikimate 1-carboxyvinyltransferase HAMAP-Rule MF_00210
PRO_0000088224

Sequences

Sequence LengthMass (Da)Tools
Q6HHF8 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: D8B3CC699D0DE108

FASTA42945,156
        10         20         30         40         50         60 
MKERTIQPVN NGLNGNITIP GDKSISHRAV MFGAIAEGTT TIKGFLPGAD CLSTISCFKE 

        70         80         90        100        110        120 
MGVDIVQDGD EVTVVGKGLE GLQEPKAVLD VGNSGTTIRL MSGILANTPF FSCVQGDASI 

       130        140        150        160        170        180 
AKRPMKRVTN PLKQMGANID GREEGTFTPL TVRGGDLKAI EYTSPVASAQ VKSAILLAGL 

       190        200        210        220        230        240 
RAEGVTAVTE PHISRDHTER MLEAFGVKVT REGKTVKLAG GQKLTATDVQ VPGDVSSAAF 

       250        260        270        280        290        300 
FLVAGAIIPN SKLVLENVGM NPTRTGIIDV LEKMGATFTV EPINEGASEP AANITIETSS 

       310        320        330        340        350        360 
LKGIEIGGDI IPRLIDEIPV IALAATQAEG ITVIKDAHEL KVKETNRIDT VVAELTKLGA 

       370        380        390        400        410        420 
RIEATDDGMI IYGKSALKGN TVNSYGDHRI GMMLAIAGCI AEGKTIIEDA EAVGVSYPTF 


FEELQKLAK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017355 Genomic DNA. Translation: AAT61256.1.
RefSeqYP_037018.1. NC_005957.1.

3D structure databases

ProteinModelPortalQ6HHF8.
SMRQ6HHF8. Positions 6-428.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING281309.BT9727_2694.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAT61256; AAT61256; BT9727_2694.
GeneID2853981.
KEGGbtk:BT9727_2694.
PATRIC18986267. VBIBacThu119411_2860.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0128.
HOGENOMHOG000247371.
KOK00800.
OMAGADIEWG.
OrthoDBEOG6Z6FZ4.
ProtClustDBPRK02427.

Enzyme and pathway databases

BioCycBTHU281309:GJID-2772-MONOMER.
UniPathwayUPA00053; UER00089.

Family and domain databases

Gene3D3.65.10.10. 2 hits.
HAMAPMF_00210. EPSP_synth.
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. SSF55205. 1 hit.
TIGRFAMsTIGR01356. aroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_BACHK
AccessionPrimary (citable) accession number: Q6HHF8
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: July 19, 2004
Last modified: February 19, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways