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Protein

Arsenate reductase

Gene

arsC

Organism
Bacillus thuringiensis subsp. konkukian (strain 97-27)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].UniRule annotation

Catalytic activityi

Arsenate + thioredoxin = arsenite + thioredoxin disulfide + H2O.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei11NucleophileUniRule annotation1
Active sitei83NucleophileUniRule annotation1
Active sitei90NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processArsenical resistance

Enzyme and pathway databases

BioCyciBTHU281309:G1G14-3040-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arsenate reductaseUniRule annotation (EC:1.20.4.4UniRule annotation)
Gene namesi
Name:arsCUniRule annotation
Ordered Locus Names:BT9727_2963
OrganismiBacillus thuringiensis subsp. konkukian (strain 97-27)
Taxonomic identifieri281309 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000001301 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001625211 – 134Arsenate reductaseAdd BLAST134

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi11 ↔ 83Redox-active; alternateUniRule annotation
Disulfide bondi83 ↔ 90Redox-active; alternateUniRule annotation

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliQ6HGP0
SMRiQ6HGP0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.UniRule annotation

Keywords - Domaini

Redox-active center

Phylogenomic databases

HOGENOMiHOG000273093
KOiK03741
OMAiCSHADSV

Family and domain databases

HAMAPiMF_01624 Arsenate_reduct, 1 hit
InterProiView protein in InterPro
IPR014064 Arsenate_reductase_ArsC
IPR023485 Ptyr_pPase
IPR036196 Ptyr_pPase_sf
PfamiView protein in Pfam
PF01451 LMWPc, 1 hit
SMARTiView protein in SMART
SM00226 LMWPc, 1 hit
SUPFAMiSSF52788 SSF52788, 1 hit
TIGRFAMsiTIGR02691 arsC_pI258_fam, 1 hit

Sequencei

Sequence statusi: Complete.

Q6HGP0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENKKTIYFL CTGNSCRSQM AEAWGKQYLG DKWNVYSAGI EAHGVNPNAI
60 70 80 90 100
KAMNEVNIDI TNQTSDIIDA NILNRADLVV TLCSHADSVC PSTPPHVNRV
110 120 130
HWGFDDPAGK EWSEFQRVRD EIGERIKCFS ETGE
Length:134
Mass (Da):15,019
Last modified:July 19, 2004 - v1
Checksum:iD3ADE8FC18C608A8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017355 Genomic DNA Translation: AAT60271.1
RefSeqiWP_000428351.1, NC_005957.1
YP_037286.1, NC_005957.1

Genome annotation databases

EnsemblBacteriaiAAT60271; AAT60271; BT9727_2963
GeneIDi2853620
KEGGibtk:BT9727_2963
PATRICifig|281309.8.peg.3154

Similar proteinsi

Entry informationi

Entry nameiARSC_BACHK
AccessioniPrimary (citable) accession number: Q6HGP0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: July 19, 2004
Last modified: February 28, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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