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Protein

Guanylate kinase

Gene

gmk

Organism
Bacillus thuringiensis subsp. konkukian (strain 97-27)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi13 – 20ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:BT9727_3612
OrganismiBacillus thuringiensis subsp. konkukian (strain 97-27)
Taxonomic identifieri281309 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000001301 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001704961 – 205Guanylate kinaseAdd BLAST205

Structurei

3D structure databases

ProteinModelPortaliQ6HEU4.
SMRiQ6HEU4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 185Guanylate kinase-likeUniRule annotationAdd BLAST180

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000037639.
KOiK00942.
OMAiYGTLKSE.

Family and domain databases

HAMAPiMF_00328. Guanylate_kinase. 1 hit.
InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6HEU4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSRRGLLIV LSGPSGVGKG TVRKELFSHE DTRFQYSISV TTRKPREGEV
60 70 80 90 100
DGVDYFFKER EEFEEMIRNE KLLEWAEFVG NYYGTPIDYV EKTLQEGKDV
110 120 130 140 150
FLEIEVQGAI QVKKAFPEGV FIFLAPPSLS ELKNRIVGRG TETEDVIENR
160 170 180 190 200
LTVAKEEIDM MDAYDYVVEN DQVELACERI KAIVVGEHCR RERVAKYYKE

MTEGL
Length:205
Mass (Da):23,677
Last modified:March 15, 2005 - v2
Checksum:iBF987D07E1D8E531
GO

Sequence cautioni

The sequence AAT60627 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017355 Genomic DNA. Translation: AAT60627.1. Different initiation.
RefSeqiWP_011040607.1. NC_005957.1.
YP_037932.1. NC_005957.1.

Genome annotation databases

EnsemblBacteriaiAAT60627; AAT60627; BT9727_3612.
GeneIDi2854107.
KEGGibtk:BT9727_3612.
PATRICifig|281309.8.peg.3850.

Similar proteinsi

Entry informationi

Entry nameiKGUA_BACHK
AccessioniPrimary (citable) accession number: Q6HEU4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: March 15, 2005
Last modified: August 30, 2017
This is version 82 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families