Reviewed, UniProtKB/Swiss-Prot Q6HEJ9 (TGL_BACHK)

Names and origin

Protein names

Recommended name:
    Protein-glutamine gamma-glutamyltransferase
    EC=2.3.2.13
Alternative name(s):
    Transglutaminase
      Short name=TGase

Gene names

Name:	tgl
Ordered Locus Names:	BT9727_3708

Organism

Bacillus thuringiensis subsp. konkukian [Complete proteome] [HAMAP]

Taxonomic identifier

180856 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	276 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links By similarity. HAMAP MF_00727
Catalytic activity	Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH3. HAMAP MF_00727
Sequence similarities	Belongs to the bacillus TGase family.

Ontologies

Keywords
Biological process	Sporulation
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sporulation resulting in formation of a cellular spore Inferred from electronic annotation. Source: HAMAP
Molecular function	acyltransferase activity Inferred from electronic annotation. Source: UniProtKB-KW protein-glutamine gamma-glutamyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 276	276	Protein-glutamine gamma-glutamyltransferase HAMAP MF_00727		PRO_1000045889

Sequences

	Sequence		Length	Mass (Da)
	Q6HEJ9-1 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: 783EA7E21E9A3D30	FASTA	276	31,459
	10 20 30 40 50 60 MIVIGRSIVH PYITNEYEPF AAEKQQILSI MAGNQEIYSF RTSDELSFDL NLRVNIITSA 70 80 90 100 110 120 LELFQSGFQF RTFQQSFCNP QYWKRTSLGG FELLPNIPPS IAIQDIFKNG KLYGTECATA 130 140 150 160 170 180 MIIIFYKALL SLYEKETFNR LFANLLLYTW DYDQDLKLIT KTGGDLVPGD LVYFKNPQVN 190 200 210 220 230 240 PATIEWQGEN TIYLGNFFFY GHGVGVKTKE EIIYALNERR VPYAFISAFL TDTITRIDSR 250 260 270 LMSYHASPST PQTSIGFIPI RDDAIVATVG NTTTVY

References

[1]

"Pathogenomic sequence analysis of Bacillus cereus and Bacillus thuringiensis isolates closely related to Bacillus anthracis." Han C.S., Xie G., Challacombe J.F., Altherr M.R., Bhotika S.S., Bruce D., Campbell C.S., Campbell M.L., Chen J., Chertkov O., Cleland C., Dimitrijevic M., Doggett N.A., Fawcett J.J., Glavina T., Goodwin L.A., Hill K.K., Hitchcock P. , Jackson P.J., Keim P., Kewalramani A.R., Longmire J., Lucas S., Malfatti S., McMurry K., Meincke L.J., Misra M., Moseman B.L., Mundt M., Munk A.C., Okinaka R.T., Parson-Quintana B., Reilly L.P., Richardson P., Robinson D.L., Rubin E., Saunders E., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Ticknor L.O., Wills P.L., Brettin T.S., Gilna P. J. Bacteriol. 188:3382-3390(2006) [PubMed: 16621833] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 97-27.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017355 Genomic DNA. Translation: AAT63084.1.
RefSeq	YP_038027.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2855089.
GenomeReviews	Gene locus BT9727_3708 in contig AE017355_GR.
KEGG	btk:BT9727_3708.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG339895.
OMA	FECATAI.
Enzyme and pathway databases
BioCyc	BTHU281309:BT9727_3708-MONOMER.
Family and domain databases
HAMAP	MF_00727. Tgl. [Tree]
InterPro	IPR020916. Gln_gamma-glutamyltransferase. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TGL_BACHK

Accession

Primary (citable) accession number: Q6HEJ9

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	July 19, 2004
Last modified:	January 19, 2010
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)