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Q6HDB8 (APT_BACHK) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Adenine phosphoribosyltransferase
Short name=APRT
EC=2.4.2.7
Gene names
Name:apt
Ordered Locus Names:BT9727_4141
OrganismBacillus thuringiensis subsp. konkukian (strain 97-27) [Complete proteome] [HAMAP]
Taxonomic identifier281309 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length170 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. HAMAP MF_00004

Catalytic activity

AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_00004

Pathway

Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1. HAMAP MF_00004

Subunit structure

Homodimer By similarity. HAMAP MF_00004

Subcellular location

Cytoplasm HAMAP MF_00004.

Sequence similarities

Belongs to the purine/pyrimidine phosphoribosyltransferase family.

Ontologies

Keywords
   Biological processPurine salvage
   Cellular componentCytoplasm
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processadenine salvage

Inferred from electronic annotation. Source: InterPro

purine ribonucleoside salvage

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionadenine phosphoribosyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 170170Adenine phosphoribosyltransferase HAMAP MF_00004
PRO_0000149351

Sequences

Sequence LengthMass (Da)Tools
Q6HDB8 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 148BA98F47CF8FFC

FASTA17018,644
        10         20         30         40         50         60 
MDFKQHIAIV PDYPKEGIVF KDITPLMNDG KAYKAATDAI VEYAKERDID LVVGPEARGF 

        70         80         90        100        110        120 
IIGCPVSYAL EVGFAPVRKL GKLPREVITV DYGKEYGKDV LTIHKDAIKP GQRVLITDDL 

       130        140        150        160        170 
LATGGTIEAT IKLVEELGGV VAGIAFLVEL TYLDGRKMLD GYDVLVLEKY

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017355 Genomic DNA. Translation: AAT60830.1.
RefSeqYP_038458.1. NC_005957.1.

3D structure databases

ProteinModelPortalQ6HDB8.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000072811; EBBACP00000070897; EBBACG00000072802.
GeneID2857393.
GenomeReviewsGene locus BT9727_4141 in contig AE017355_GR.
KEGGbtk:BT9727_4141.
PATRIC18989389. VBIBacThu119411_4419.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000001499.
HOGENOMHBG703830.
OMAGMEARGF.
ProtClustDBPRK02304.

Enzyme and pathway databases

BioCycBTHU281309:BT9727_4141-MONOMER.

Family and domain databases

HAMAPMF_00004. Aden_phosphoribosyltr.
[Tree]
InterProIPR005764. Ade_phspho_trans.
IPR000836. PRibTrfase.
[Graphical view]
KOK00759.
PfamPF00156. Pribosyltran. 1 hit.
[Graphical view]
TIGRFAMsTIGR01090. Apt. 1 hit.
PROSITEPS00103. PUR_PYR_PR_TRANSFER. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAPT_BACHK
AccessionPrimary (citable) accession number: Q6HDB8
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: July 19, 2004
Last modified: January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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