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Protein
Submitted name:

Sialyltransferase ST3Gal-I

Gene

St3gal1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei105 – 1051SubstrateUniRule annotation
Binding sitei147 – 1471SubstrateUniRule annotation
Binding sitei170 – 1701SubstrateUniRule annotation
Binding sitei230 – 2301SubstrateUniRule annotation
Binding sitei266 – 2661SubstrateUniRule annotation
Binding sitei270 – 2701Substrate; via amide nitrogenUniRule annotation
Binding sitei290 – 2901Substrate; via amide nitrogenUniRule annotation
Binding sitei299 – 2991SubstrateUniRule annotation
Binding sitei316 – 3161SubstrateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseSAAS annotationImported, Transferase

Protein family/group databases

CAZyiGT29. Glycosyltransferase Family 29.

Names & Taxonomyi

Protein namesi
Submitted name:
Sialyltransferase ST3Gal-IImported (EC:2.4.99.4Imported)
Gene namesi
Name:St3gal1Imported
Synonyms:siat4AImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi1309373. St3gal1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatusSAAS annotation, Membrane

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi142 ↔ 281UniRule annotation

Proteomic databases

PaxDbiQ6H8N0.
PRIDEiQ6H8N0.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000010980.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 29 family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG2692. Eukaryota.
ENOG410XT8P. LUCA.
HOGENOMiHOG000126811.
HOVERGENiHBG054227.
KOiK00780.
PhylomeDBiQ6H8N0.

Family and domain databases

InterProiIPR001675. Glyco_trans_29.
IPR012163. Sialyl_trans.
[Graphical view]
PfamiPF00777. Glyco_transf_29. 1 hit.
[Graphical view]
PIRSFiPIRSF005557. Sialyl_trans. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6H8N0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVNMRKRTLK YLTFFLLFIF LTSFVLNYSN SGVPSAWFPK QMVLEFSENF
60 70 80 90 100
RKFIKSQPCT CRHCISQGKV SYWFDQRFNK TMQPLLTVHN ALMEEDTYRW
110 120 130 140 150
WLRLQRERKP NNLSDTVKEL FRLVPGNVDP MLNKRLVGCR RCAVVGNSGN
160 170 180 190 200
LKDSSYGPEI DSHDFVLRMN RAPTVGFEAD VGSRTTHHLV YPESFRELGE
210 220 230 240 250
NVNMVLVPFK ITDLQWVISA TTTGTITHTY VPVPPKIKVK QEKILIYHPA
260 270 280 290 300
FIKYVFDNWL QGHGRYPSTG ILSVIFSIHI CDEVDLYGFG ADSKGNWHHY
310 320 330 340
WENNPSAGAF RKTGVHDGDF EYNVTTTLAA INKIRIFKGR
Length:340
Mass (Da):39,349
Last modified:July 19, 2004 - v1
Checksum:i097127392D3C7D7B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ748840 mRNA. Translation: CAG44449.1.
RefSeqiNP_001013237.1. NM_001013219.1.
UniGeneiRn.104514.
Rn.8110.

Genome annotation databases

GeneIDi362924.
KEGGirno:362924.
UCSCiRGD:1309373. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ748840 mRNA. Translation: CAG44449.1.
RefSeqiNP_001013237.1. NM_001013219.1.
UniGeneiRn.104514.
Rn.8110.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000010980.

Protein family/group databases

CAZyiGT29. Glycosyltransferase Family 29.

Proteomic databases

PaxDbiQ6H8N0.
PRIDEiQ6H8N0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi362924.
KEGGirno:362924.
UCSCiRGD:1309373. rat.

Organism-specific databases

CTDi6482.
RGDi1309373. St3gal1.

Phylogenomic databases

eggNOGiKOG2692. Eukaryota.
ENOG410XT8P. LUCA.
HOGENOMiHOG000126811.
HOVERGENiHBG054227.
KOiK00780.
PhylomeDBiQ6H8N0.

Miscellaneous databases

NextBioi681797.

Family and domain databases

InterProiIPR001675. Glyco_trans_29.
IPR012163. Sialyl_trans.
[Graphical view]
PfamiPF00777. Glyco_transf_29. 1 hit.
[Graphical view]
PIRSFiPIRSF005557. Sialyl_trans. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach."
    Harduin-Lepers A., Mollicone R., Delannoy P., Oriol R.
    Glycobiology 15:805-817(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: WistarImported.

Entry informationi

Entry nameiQ6H8N0_RAT
AccessioniPrimary (citable) accession number: Q6H8N0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 19, 2004
Last sequence update: July 19, 2004
Last modified: May 11, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.