Q6H7J4 (P2C23_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative protein phosphatase 2C 23
Short name=OsPP2C23
EC=3.1.3.16

Gene names

Ordered Locus Names:	Os02g0633700, LOC_Os02g42250
ORF Names:	OJ1643_A10.22

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	319 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Catalytic activity	A phosphoprotein + H2O = a protein + phosphate.
Cofactor	Binds 2 magnesium ions per subunit By similarity.
Sequence similarities	Belongs to the PP2C family. Contains 1 PP2C-like domain.
Caution	Although related to the protein phosphatase 2C family, lacks 1 of the conserved residues that bind manganese, suggesting it has no phosphatase activity. Could be the product of a pseudogene.

Ontologies

Keywords
Ligand	Magnesium Manganese Metal-binding
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	metabolic process Inferred from electronic annotation. Source: GOC
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoprotein phosphatase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 319	319	Putative protein phosphatase 2C 23		PRO_0000363269
Regions
	Domain	78 – 314	237	PP2C-like
Sites
	Metal binding	102	1	Manganese 1; via carbonyl oxygen By similarity
	Metal binding	235	1	Manganese 2 By similarity
	Metal binding	305	1	Manganese 2 By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6H7J4 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: B35E3988B0F66490	FASTA	319	34,728
	10 20 30 40 50 60 MEKRMETLEQ IKETLRETSK LVPDIVRAAV GLEHHYQTVE LPHDDGCVKS FAAAFLRPQA 70 80 90 100 110 120 QEQAHGDGEV QQAVRMESAS CYVPDHDEDA HFVHDAAGVV GGYRRRVGVD AGAFSRGLMT 130 140 150 160 170 180 SAFAQLVTAE PGTPVCPYTL LERAYEETLE SGAQGGSTAV ILSLADGNVL RWAYIGDSAF 190 200 210 220 230 240 AVLRDGRVVV RSVQQQRYFN APYYLGGRRG DEGMTVGMVG EMKVRRGDVV VAGTDGLFDN 250 260 270 280 290 300 MSDAELEKVV QIGTALGFSP KNMADIIGGT AYEMSRCLLK DSPFAVEWRK QHENEEGHFY 310 GGKVDDITVV VACIVSSDS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis." Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y. BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP004192 Genomic DNA. Translation: BAD25305.1.
3D structure databases
ProteinModelPortal	Q6H7J4.
ModBase	Search...
Proteomic databases
PRIDE	Q6H7J4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os02g42250.1; LOC_Os02g42250.1; LOC_Os02g42250.
Organism-specific databases
Gramene	Q6H7J4.
Phylogenomic databases
eggNOG	NOG280253.
OMA	DARPCAP.
Gene expression databases
ArrayExpress	Q6H7J4.
Family and domain databases
Gene3D	3.60.40.10. 1 hit.
InterPro	IPR001932. PP2C-like. [Graphical view]
Pfam	PF07228. SpoIIE. 1 hit. [Graphical view]
SMART	SM00331. PP2C_SIG. 1 hit. SM00332. PP2Cc. 1 hit. [Graphical view]
SUPFAM	SSF81606. PP2C-related. 1 hit.
PROSITE	PS01032. PP2C. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P2C23_ORYSJ

Accession

Primary (citable) accession number: Q6H7J4

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	July 19, 2004
Last modified:	April 3, 2013
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program