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Q6H501 (HKT6_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable cation transporter HKT6

Short name=OsHKT6
Gene names
Name:HKT6
Ordered Locus Names:Os02g0175000, LOC_Os02g07830
ORF Names:OSJNBa0073A21.31
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length530 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Probable cation transporter. May be involved in regulation of K+/Na+ homeostasis.

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Tissue specificity

Weakly expressed. Ref.1

Domain

HKT transporters are proposed to contain 4 pore-forming regions enclosed by transmembrane segments with each containing a potassium channel-like selectivity filter motif.

Sequence similarities

Belongs to the TrkH potassium transport family. HKT (TC 2.A.38.3) subfamily. [View classification]

Ontologies

Keywords
   Biological processIon transport
Transport
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processresponse to salt stress

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functioncation transmembrane transporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 530530Probable cation transporter HKT6
PRO_0000070470

Regions

Topological domain1 – 4646Cytoplasmic Potential
Transmembrane47 – 6721Helical; Name=1; Potential
Transmembrane108 – 12821Helical; Name=2; Potential
Topological domain129 – 19062Cytoplasmic Potential
Transmembrane191 – 21121Helical; Name=3; Potential
Transmembrane264 – 28421Helical; Name=4; Potential
Topological domain285 – 32137Cytoplasmic Potential
Transmembrane322 – 34221Helical; Name=5; Potential
Transmembrane383 – 40321Helical; Name=6; Potential
Topological domain404 – 42118Cytoplasmic Potential
Transmembrane422 – 44221Helical; Name=7; Potential
Transmembrane494 – 51421Helical; Name=8; Potential
Topological domain515 – 53016Cytoplasmic Potential

Experimental info

Sequence conflict4651V → VS in CAD37184. Ref.1
Sequence conflict4651V → VS in CAD37185. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q6H501 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 1ECC845AA8677C44

FASTA53059,217
        10         20         30         40         50         60 
MNHCLVVSHK KLQTFRTFAA SKFSSFTKSA QKSIKYSFQF IYQNNPLFVH VAYFALISFA 

        70         80         90        100        110        120 
GYGSLKVLKP RDKSNTLKDL DVLFTSVSAS TVSSMATVEM EDFSSAQLWV LTILMLIGGE 

       130        140        150        160        170        180 
VFTSMLGIHF MRAEFGTKES VSTRDHSPCI DIESITSTKF GPSTQGTKVT VSFSELRMEN 

       190        200        210        220        230        240 
GGHVEPKTIK FLGFVVMGYL LITNLGGSLL IYLYLNLVPS AHKILKRKGI GIIVFSVFTA 

       250        260        270        280        290        300 
ISSVGNCGFT PVNENMIIFQ KNSILLLLIL PQILAGNTLF APCLRLMVWS LEKITGKKDC 

       310        320        330        340        350        360 
RYILEYPKAI GYKHLMSTRE SVYLTLTVVS LIILQTVLFL SLEWSSVALD GMSNYQKIVS 

       370        380        390        400        410        420 
ALFQSVNARH AGESVTDLSN LSSAILVLYT IMMYLPGYTS FLPRHDGEDS KTEKINKRKG 

       430        440        450        460        470        480 
LLENWIFSHM SYLAIFVMLI CITERDSMAT DPLNFNVFSI LFEVVAYGNV GFSVGYSCKR 

       490        500        510        520        530 
LLNHDARCKD ASYGFAGKWS DNGKAILIIV MLFGRLKTFN MKGGRAWKLR 

« Hide

References

« Hide 'large scale' references
[1]"Sodium transport and HKT transporters: the rice model."
Garciadeblas B., Senn M.E., Banuelos M.A., Rodriguez-Navarro A.
Plant J. 34:788-801(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], TISSUE SPECIFICITY, NOMENCLATURE.
Strain: cv. Nipponbare.
Tissue: Root.
[2]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ491817 Genomic DNA. Translation: CAD37184.1.
AJ491818 mRNA. Translation: CAD37185.1.
AP005772 Genomic DNA. Translation: BAD26198.1.
AP003992 Genomic DNA. Translation: BAD27606.1.
RefSeqNP_001046052.1. NM_001052587.1.
UniGeneOs.79807.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4328468.
KEGGosa:4328468.

Organism-specific databases

GrameneQ6H501.

Phylogenomic databases

eggNOGCOG0168.

Family and domain databases

InterProIPR003445. Cat_transpt.
[Graphical view]
PfamPF02386. TrkH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHKT6_ORYSJ
AccessionPrimary (citable) accession number: Q6H501
Secondary accession number(s): Q8L4V1
Entry history
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: July 19, 2004
Last modified: May 14, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations