Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q6GZP5

- RNC_FRG3G

UniProt

Q6GZP5 - RNC_FRG3G

Protein

Putative ribonuclease 3

Gene

FV3-080L

Organism
Frog virus 3 (isolate Goorha) (FV-3)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (19 Jul 2004)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Digests double-stranded RNA.By similarity

    Catalytic activityi

    Endonucleolytic cleavage to 5'-phosphomonoester.

    GO - Molecular functioni

    1. ribonuclease III activity Source: UniProtKB-EC
    2. RNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. RNA processing Source: InterPro

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Ligandi

    RNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative ribonuclease 3 (EC:3.1.26.3)
    Alternative name(s):
    Ribonuclease III
    Short name:
    RNase III
    Gene namesi
    ORF Names:FV3-080L
    OrganismiFrog virus 3 (isolate Goorha) (FV-3)
    Taxonomic identifieri654924 [NCBI]
    Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeRanavirus
    Virus hostiAmbystoma (mole salamanders) [TaxID: 8295]
    Hyla versicolor (chameleon treefrog) [TaxID: 30343]
    Lithobates pipiens (Northern leopard frog) (Rana pipiens) [TaxID: 8404]
    Notophthalmus viridescens (Eastern newt) (Triturus viridescens) [TaxID: 8316]
    Rana sylvatica (Wood frog) [TaxID: 45438]
    ProteomesiUP000008770: Genome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 371371Putative ribonuclease 3PRO_0000410590Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ6GZP5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini10 – 136127RNase IIIPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the IIV-6 142R family.Curated
    Contains 1 RNase III domain.PROSITE-ProRule annotation

    Family and domain databases

    Gene3Di1.10.1520.10. 1 hit.
    InterProiIPR000999. RNase_III_dom.
    [Graphical view]
    PfamiPF00636. Ribonuclease_3. 1 hit.
    [Graphical view]
    SMARTiSM00535. RIBOc. 1 hit.
    [Graphical view]
    SUPFAMiSSF69065. SSF69065. 1 hit.
    PROSITEiPS50142. RNASE_3_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6GZP5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEGWLGNLLA KSVKDKYIPV IVGRRDLWNK VFTPKSVNPD DNYEALEIVG    50
    DGVASYFFPS YFLKRFPQLN SPKGVKTVAR LKIYYGSKKS FSSIADSLGF 100
    WKFIRSGPVP VNPSTRESLL EDTFEAFLGA VCMAVDDEYS IDGLGAVVAY 150
    KIMADIFDDM DISLEYTALF DTVTRLKELM DVKKDVLGGD AVYNHRGDTT 200
    VITLKGRVIG KATGAIKRDR AKEAAGQALD LLRREGHFRE HDDDAVVKVA 250
    KGPAGDGLVV AQSALGGFTV FGAESGVVEG SGGTVAQALS RVVGTKRPSA 300
    VEVAGGDYKS LLKEYLESVG ETDSVNYIHE GVTVTMTRKG KPVATANHLV 350
    KKVREQLASR DYYRTVHAKG V 371
    Length:371
    Mass (Da):40,362
    Last modified:July 19, 2004 - v1
    Checksum:i86638E1130E44E6A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY548484 Genomic DNA. Translation: AAT09740.1.
    RefSeqiYP_031659.1. NC_005946.1.

    Genome annotation databases

    GeneIDi2947799.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY548484 Genomic DNA. Translation: AAT09740.1 .
    RefSeqi YP_031659.1. NC_005946.1.

    3D structure databases

    ProteinModelPortali Q6GZP5.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 2947799.

    Family and domain databases

    Gene3Di 1.10.1520.10. 1 hit.
    InterProi IPR000999. RNase_III_dom.
    [Graphical view ]
    Pfami PF00636. Ribonuclease_3. 1 hit.
    [Graphical view ]
    SMARTi SM00535. RIBOc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF69065. SSF69065. 1 hit.
    PROSITEi PS50142. RNASE_3_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Comparative genomic analyses of frog virus 3, type species of the genus Ranavirus (family Iridoviridae)."
      Tan W.G., Barkman T.J., Gregory Chinchar V., Essani K.
      Virology 323:70-84(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiRNC_FRG3G
    AccessioniPrimary (citable) accession number: Q6GZP5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 28, 2011
    Last sequence update: July 19, 2004
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3