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Protein

Putative ribonuclease 3

Gene

FV3-080L

Organism
Frog virus 3 (isolate Goorha) (FV-3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Digests double-stranded RNA.By similarity

Catalytic activityi

Endonucleolytic cleavage to 5'-phosphomonoester.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease, RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative ribonuclease 3 (EC:3.1.26.3)
Alternative name(s):
Ribonuclease III
Short name:
RNase III
Gene namesi
ORF Names:FV3-080L
OrganismiFrog virus 3 (isolate Goorha) (FV-3)
Taxonomic identifieri654924 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeAlphairidovirinaeRanavirus
Virus hostiAmbystoma (mole salamanders) [TaxID: 8295]
Dryophytes versicolor (chameleon treefrog) [TaxID: 30343]
Lithobates pipiens (Northern leopard frog) (Rana pipiens) [TaxID: 8404]
Notophthalmus viridescens (Eastern newt) (Triturus viridescens) [TaxID: 8316]
Rana sylvatica (Wood frog) [TaxID: 45438]
Proteomesi
  • UP000008770 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004105901 – 371Putative ribonuclease 3Add BLAST371

Structurei

3D structure databases

ProteinModelPortaliQ6GZP5.
SMRiQ6GZP5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 136RNase IIIPROSITE-ProRule annotationAdd BLAST127

Sequence similaritiesi

Belongs to the IIV-6 142R family.Curated

Phylogenomic databases

OrthoDBiVOG090000RK.

Family and domain databases

CDDicd00593. RIBOc. 1 hit.
Gene3Di1.10.1520.10. 1 hit.
InterProiView protein in InterPro
IPR000999. RNase_III_dom.
PfamiView protein in Pfam
PF00636. Ribonuclease_3. 1 hit.
SMARTiView protein in SMART
SM00535. RIBOc. 1 hit.
SUPFAMiSSF69065. SSF69065. 1 hit.
PROSITEiView protein in PROSITE
PS50142. RNASE_3_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6GZP5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGWLGNLLA KSVKDKYIPV IVGRRDLWNK VFTPKSVNPD DNYEALEIVG
60 70 80 90 100
DGVASYFFPS YFLKRFPQLN SPKGVKTVAR LKIYYGSKKS FSSIADSLGF
110 120 130 140 150
WKFIRSGPVP VNPSTRESLL EDTFEAFLGA VCMAVDDEYS IDGLGAVVAY
160 170 180 190 200
KIMADIFDDM DISLEYTALF DTVTRLKELM DVKKDVLGGD AVYNHRGDTT
210 220 230 240 250
VITLKGRVIG KATGAIKRDR AKEAAGQALD LLRREGHFRE HDDDAVVKVA
260 270 280 290 300
KGPAGDGLVV AQSALGGFTV FGAESGVVEG SGGTVAQALS RVVGTKRPSA
310 320 330 340 350
VEVAGGDYKS LLKEYLESVG ETDSVNYIHE GVTVTMTRKG KPVATANHLV
360 370
KKVREQLASR DYYRTVHAKG V
Length:371
Mass (Da):40,362
Last modified:July 19, 2004 - v1
Checksum:i86638E1130E44E6A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY548484 Genomic DNA. Translation: AAT09740.1.
RefSeqiYP_031659.1. NC_005946.1.

Genome annotation databases

GeneIDi2947799.
KEGGivg:2947799.

Similar proteinsi

Entry informationi

Entry nameiRNC_FRG3G
AccessioniPrimary (citable) accession number: Q6GZP5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 28, 2011
Last sequence update: July 19, 2004
Last modified: September 27, 2017
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families