Q6GTM5 (Q6GTM5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like EMBL AAH50427.1

Submitted name:
Sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, fungal)-like variant EMBL BAD96406.1
Submitted name:
Sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, fungal)-like, isoform CRA_b EMBL EAW67520.1
Submitted name:
cDNA, FLJ93018, highly similar to Homo sapiens sterol-C5-desaturase (ERG3 delta-5-desaturase homolog,fungal)-like (SC5DL), mRNA EMBL BAG35518.1

Gene names

Name:	SC5DL EMBL AAH50427.1
ORF Names:	hCG_1641241 EMBL EAW67520.1

Organism

Homo sapiens (Human) EMBL AAH50427.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	299 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS006694
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	iron ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAD96406.1

Sequences

	Sequence		Length	Mass (Da)
	Q6GTM5 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 9EF8B20D522FAA56	FASTA	299	35,301
	10 20 30 40 50 60 MDLVLRVADY YFFTPYVYPA TWPEDDIFRQ AISLLIVTNV GAYILYFFCA TLSYYFVFDH 70 80 90 100 110 120 ALMKHPQFLK NQVRREIKFT VQALPWISIL TVALFLLEIR GYSKLHDDLG EFPYGLFELV 130 140 150 160 170 180 VSIISFLFFT DMFIYWIHRG LHHRLVYKRL HKPHHIWKIP TPFASHAFHP IDGFLQSLPY 190 200 210 220 230 240 HIYPFIFPLH KVVYLSLYIL VNIWTISIHD GDFRVPQILQ PFINGSAHHT DHHMFFDYNY 250 260 270 280 290 GQYFTLWDRI GGSFKNPSSF EGKGPLSYVK EMTEGKRSSH SGNGCKNEKL FNGEFTKTE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library." Suzuki Y., Yoshitomo K., Maruyama K., Suyama A., Sugano S. Gene 200:149-156(1997) [PubMed: 9373149] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAD96406.1 and Kidney EMBL BAD96861.1.
[2]	"Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides." Maruyama K., Sugano S. Gene 138:171-174(1994) [PubMed: 8125298] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAD96406.1 and Kidney EMBL BAD96861.1.
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Skin EMBL AAH50427.1.
[4]	"NEDO functional analysis of protein and research application project." Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[5]	Suzuki Y., Sugano S., Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S. Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAD96406.1 and Kidney EMBL BAD96861.1.
[6]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC050427 mRNA. Translation: AAH50427.1. AK222686 mRNA. Translation: BAD96406.1. AK223141 mRNA. Translation: BAD96861.1. AK312634 mRNA. Translation: BAG35518.1. CH471065 Genomic DNA. Translation: EAW67520.1.
IPI	IPI00027181.
RefSeq	NP_001020127.1. NM_001024956.2. NP_008849.2. NM_006918.4.
UniGene	Hs.287749.
3D structure databases
ProteinModelPortal	Q6GTM5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6GTM5.
Proteomic databases
PRIDE	Q6GTM5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6309.
KEGG	hsa:6309.
UCSC	uc001pxt.1. human.
Organism-specific databases
CTD	6309.
Phylogenomic databases
GeneTree	ENSGT00550000075101.
HOVERGEN	HBG012628.
OMA	PWISIPT.
PhylomeDB	Q6GTM5.
Gene expression databases
ArrayExpress	Q6GTM5.
Bgee	Q6GTM5.
Family and domain databases
InterPro	IPR006694. Fatty_acid_hydroxylase. [Graphical view]
KO	K00227.
Pfam	PF04116. FA_hydroxylase. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	24491.

Entry information

Entry name

Q6GTM5_HUMAN

Accession

Primary (citable) accession number: Q6GTM5

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	November 16, 2011
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.