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Q6GR25

- PPTC7_XENLA

UniProt

Q6GR25 - PPTC7_XENLA

Protein

Protein phosphatase PTC7 homolog

Gene

pptc7

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (19 Jul 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Magnesium or manganese.Curated

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi71 – 711Manganese 1By similarity
    Metal bindingi71 – 711Manganese 2By similarity
    Metal bindingi72 – 721Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi216 – 2161Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphoprotein phosphatase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein phosphatase PTC7 homolog (EC:3.1.3.16)
    Gene namesi
    Name:pptc7
    OrganismiXenopus laevis (African clawed frog)
    Taxonomic identifieri8355 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

    Organism-specific databases

    XenbaseiXB-GENE-1012927. pptc7.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 297297Protein phosphatase PTC7 homologPRO_0000328748Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ6GR25.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini40 – 290251PP2C-likeAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Phylogenomic databases

    HOVERGENiHBG060636.
    KOiK17508.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    [Graphical view]
    PfamiPF07228. SpoIIE. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q6GR25-1 [UniParc]FASTAAdd to Basket

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    MFSVLSCGRL VARAVFGGLS QTDSRDYSLV TASCGFGKDA RKGILKKGMC    50
    YGDDACFIAR HRTADVLGVA DGVGGWRDYG VDPSQFSETL MRTCERLVKE 100
    GRFVPTNPVG ILTSSYRELL QNKVPLLGSS TACLVVLDRT SHRLHTANLG 150
    DSGFLVVRAG EVVHRSDEQQ HYFNTPFQLS IAPPEAEGAV LSDSPDAADS 200
    NSFDVQLGDI ILTATDGLFD NMPDYMILQE LKKLKNTNYE SIQQTARSIA 250
    EQAHDLAYDP NYMSPFAQFA CDYGLNVRGG KPDDITVLLS IVAEYTD 297
    Length:297
    Mass (Da):32,427
    Last modified:July 19, 2004 - v1
    Checksum:iE4AEF12609A04725
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC071109 mRNA. Translation: AAH71109.1.
    RefSeqiNP_001085343.1. NM_001091874.1.
    UniGeneiXl.53093.

    Genome annotation databases

    GeneIDi443769.
    KEGGixla:443769.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC071109 mRNA. Translation: AAH71109.1 .
    RefSeqi NP_001085343.1. NM_001091874.1.
    UniGenei Xl.53093.

    3D structure databases

    ProteinModelPortali Q6GR25.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 443769.
    KEGGi xla:443769.

    Organism-specific databases

    CTDi 160760.
    Xenbasei XB-GENE-1012927. pptc7.

    Phylogenomic databases

    HOVERGENi HBG060636.
    KOi K17508.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    [Graphical view ]
    Pfami PF07228. SpoIIE. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. NIH - Xenopus Gene Collection (XGC) project
      Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Embryo.

    Entry informationi

    Entry nameiPPTC7_XENLA
    AccessioniPrimary (citable) accession number: Q6GR25
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 8, 2008
    Last sequence update: July 19, 2004
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3