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Protein

Protein phosphatase PTC7 homolog

Gene

pptc7

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+Curated, Mn2+Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi71Manganese 1By similarity1
Metal bindingi71Manganese 2By similarity1
Metal bindingi72Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi216Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein phosphatase PTC7 homolog (EC:3.1.3.16)
Gene namesi
Name:pptc7
OrganismiXenopus laevis (African clawed frog)
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-1012927. pptc7.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003287481 – 297Protein phosphatase PTC7 homologAdd BLAST297

Structurei

3D structure databases

ProteinModelPortaliQ6GR25.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 292PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST260

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

HOVERGENiHBG060636.
KOiK17508.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR036457. PPM-type_dom_sf.
IPR001932. PPM-type_phosphatase_dom.
PfamiView protein in Pfam
PF07228. SpoIIE. 1 hit.
SMARTiView protein in SMART
SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiView protein in PROSITE
PS51746. PPM_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6GR25-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFSVLSCGRL VARAVFGGLS QTDSRDYSLV TASCGFGKDA RKGILKKGMC
60 70 80 90 100
YGDDACFIAR HRTADVLGVA DGVGGWRDYG VDPSQFSETL MRTCERLVKE
110 120 130 140 150
GRFVPTNPVG ILTSSYRELL QNKVPLLGSS TACLVVLDRT SHRLHTANLG
160 170 180 190 200
DSGFLVVRAG EVVHRSDEQQ HYFNTPFQLS IAPPEAEGAV LSDSPDAADS
210 220 230 240 250
NSFDVQLGDI ILTATDGLFD NMPDYMILQE LKKLKNTNYE SIQQTARSIA
260 270 280 290
EQAHDLAYDP NYMSPFAQFA CDYGLNVRGG KPDDITVLLS IVAEYTD
Length:297
Mass (Da):32,427
Last modified:July 19, 2004 - v1
Checksum:iE4AEF12609A04725
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC071109 mRNA. Translation: AAH71109.1.
RefSeqiNP_001085343.1. NM_001091874.1.
UniGeneiXl.53093.

Genome annotation databases

GeneIDi443769.
KEGGixla:443769.

Similar proteinsi

Entry informationi

Entry nameiPPTC7_XENLA
AccessioniPrimary (citable) accession number: Q6GR25
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: July 19, 2004
Last modified: October 25, 2017
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families