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Q6GR25

- PPTC7_XENLA

UniProt

Q6GR25 - PPTC7_XENLA

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Protein

Protein phosphatase PTC7 homolog

Gene

pptc7

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+Curated, Mn2+Curated

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi71 – 711Manganese 1By similarity
Metal bindingi71 – 711Manganese 2By similarity
Metal bindingi72 – 721Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi216 – 2161Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein phosphatase PTC7 homolog (EC:3.1.3.16)
Gene namesi
Name:pptc7
OrganismiXenopus laevis (African clawed frog)
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-1012927. pptc7.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 297297Protein phosphatase PTC7 homologPRO_0000328748Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ6GR25.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini40 – 290251PP2C-likeAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PP2C-like domain.Curated

Phylogenomic databases

HOVERGENiHBG060636.
KOiK17508.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
[Graphical view]
PfamiPF07228. SpoIIE. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6GR25-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFSVLSCGRL VARAVFGGLS QTDSRDYSLV TASCGFGKDA RKGILKKGMC
60 70 80 90 100
YGDDACFIAR HRTADVLGVA DGVGGWRDYG VDPSQFSETL MRTCERLVKE
110 120 130 140 150
GRFVPTNPVG ILTSSYRELL QNKVPLLGSS TACLVVLDRT SHRLHTANLG
160 170 180 190 200
DSGFLVVRAG EVVHRSDEQQ HYFNTPFQLS IAPPEAEGAV LSDSPDAADS
210 220 230 240 250
NSFDVQLGDI ILTATDGLFD NMPDYMILQE LKKLKNTNYE SIQQTARSIA
260 270 280 290
EQAHDLAYDP NYMSPFAQFA CDYGLNVRGG KPDDITVLLS IVAEYTD
Length:297
Mass (Da):32,427
Last modified:July 19, 2004 - v1
Checksum:iE4AEF12609A04725
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC071109 mRNA. Translation: AAH71109.1.
RefSeqiNP_001085343.1. NM_001091874.1.
UniGeneiXl.53093.

Genome annotation databases

GeneIDi443769.
KEGGixla:443769.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC071109 mRNA. Translation: AAH71109.1 .
RefSeqi NP_001085343.1. NM_001091874.1.
UniGenei Xl.53093.

3D structure databases

ProteinModelPortali Q6GR25.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 443769.
KEGGi xla:443769.

Organism-specific databases

CTDi 160760.
Xenbasei XB-GENE-1012927. pptc7.

Phylogenomic databases

HOVERGENi HBG060636.
KOi K17508.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
[Graphical view ]
Pfami PF07228. SpoIIE. 1 hit.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 1 hit.
ProtoNeti Search...

Publicationsi

  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Embryo.

Entry informationi

Entry nameiPPTC7_XENLA
AccessioniPrimary (citable) accession number: Q6GR25
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: July 19, 2004
Last modified: November 26, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3