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Protein

Rab9 effector protein with kelch motifs

Gene

rabepk

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Rab9 effector required for endosome to trans-Golgi network (TGN) transport.By similarity

Enzyme and pathway databases

ReactomeiR-DRE-6811440. Retrograde transport at the Trans-Golgi-Network.

Names & Taxonomyi

Protein namesi
Recommended name:
Rab9 effector protein with kelch motifs
Gene namesi
Name:rabepk
ORF Names:zgc:91813
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 5

Organism-specific databases

ZFINiZDB-GENE-040704-52. rabepk.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002806201 – 351Rab9 effector protein with kelch motifsAdd BLAST351

Proteomic databases

PaxDbiQ6GQN7.

Expressioni

Gene expression databases

BgeeiENSDARG00000103899.
ExpressionAtlasiQ6GQN7. baseline.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000058270.

Structurei

3D structure databases

ProteinModelPortaliQ6GQN7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati54 – 102Kelch 1Add BLAST49
Repeati105 – 156Kelch 2Add BLAST52
Repeati162 – 210Kelch 3Add BLAST49
Repeati214 – 263Kelch 4Add BLAST50
Repeati264 – 313Kelch 5Add BLAST50
Repeati328 – 351Kelch 6Add BLAST24

Keywords - Domaini

Kelch repeat, Repeat

Phylogenomic databases

eggNOGiKOG0379. Eukaryota.
ENOG410Y5WM. LUCA.
GeneTreeiENSGT00760000119086.
HOGENOMiHOG000231970.
HOVERGENiHBG080504.
InParanoidiQ6GQN7.
KOiK20285.
OMAiIIPWPVT.
OrthoDBiEOG091G0IS4.
PhylomeDBiQ6GQN7.
TreeFamiTF329153.

Family and domain databases

Gene3Di2.120.10.80. 2 hits.
InterProiView protein in InterPro
IPR011043. Gal_Oxase/kelch_b-propeller.
IPR015915. Kelch-typ_b-propeller.
IPR011498. Kelch_2.
PfamiView protein in Pfam
PF07646. Kelch_2. 1 hit.
SUPFAMiSSF50965. SSF50965. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6GQN7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELIPVLEPE QKPQNRHWYV LEPTGAAPGV SVGHTCSFLP AAHHHDEDGG
60 70 80 90 100
GKGKIVIVGG ANPSGSFADS YIINLDTHQW DLPDWEGLQA RYEHCSFTPE
110 120 130 140 150
SEPQSLWVFG GAEKSTNRNC VQALRFSDGG EGRRFWQSVQ VTGVPPSGRT
160 170 180 190 200
YHTNSACVGN RLFVFSGGEA GSSAVTDAQL HVFDAVSVTW TQPDTTGTPP
210 220 230 240 250
AQRHGHVITA VGSDIYIHGG MSGEKFHSDM FTLNTESLKW QKVKAKGDLP
260 270 280 290 300
PGVAAHSSVT FNKNIFIFGG MTADGATNSM FKFQCDKQRW TLLKFEGDLP
310 320 330 340 350
PGRLDHSMCL LPWRVKMEDS EHADVQHLCF VFGGMDTQGV IFNDCLVTVL

T
Length:351
Mass (Da):38,347
Last modified:July 19, 2004 - v1
Checksum:i732D5A761C868228
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC072705 mRNA. Translation: AAH72705.1.
RefSeqiNP_001002209.1. NM_001002209.1.
XP_005171783.1. XM_005171726.3.
UniGeneiDr.17666.

Genome annotation databases

EnsembliENSDART00000170112; ENSDARP00000136816; ENSDARG00000103899.
GeneIDi431756.
KEGGidre:431756.

Similar proteinsi

Entry informationi

Entry nameiRABEK_DANRE
AccessioniPrimary (citable) accession number: Q6GQN7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: July 19, 2004
Last modified: October 25, 2017
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome