Q6GQJ4 (Q6GQJ4_XENLA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
C-raf protein EMBL AAH72748.1

Gene names

Name:

c-raf EMBL AAH72748.1

Organism

Xenopus laevis (African clawed frog) EMBL AAH72748.1

Taxonomic identifier

8355 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus

Protein attributes

Sequence length	638 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein. SAAS SAAS020454
Sequence similarities	Belongs to the protein kinase superfamily. RuleBase RU000305 Contains 1 protein kinase domain. SAAS SAAS020454

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS020454 Metal-binding SAAS SAAS020454 Nucleotide-binding Zinc SAAS SAAS020454
Molecular function	Kinase Serine/threonine-protein kinase RuleBase RU000305 SAAS SAAS020454 Transferase
Gene Ontology (GO)
Biological_process	intracellular signal transduction Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine kinase activity Inferred from electronic annotation. Source: UniProtKB-KW receptor signaling protein activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6GQJ4 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: 9C9B2BA650E2BCC7	FASTA	638	72,036
	10 20 30 40 50 60 MEHIQGAWKT LSNGFGFKES VFEGSSCMSP TIGHQFGYQR RASDDGKLSD TSKTSSTMRV 70 80 90 100 110 120 YLPNKQRTVV NVRSGMSLHD CLMKSLKVRG LQPECCAVFR LIQDPKGKLR LDWNTDAMSL 130 140 150 160 170 180 VGAELQVDFL DHVPLTTHNF VRKTFLKLAF CDICQKFLLN GFRCQTCGYK FHEHCSTKVP 190 200 210 220 230 240 TMCVDWSNIR QLLLFPNPNN IEGGSHTLPS LTMRRMRESV RIPVSSQQRY STPHPFSFST 250 260 270 280 290 300 PSPVSECSLS QRQRSTSTPN VHMVSTTMAV DSRVIEDALR SHSESGSPNN LSPTGWSNAK 310 320 330 340 350 360 APAPTHREKA ASSTGQEKNK IRPRGQRDSS YYWEIEASEV MLSSRIGSGS FGTVYKGKWH 370 380 390 400 410 420 GDVAVKILKV TDPTPEQLQA FRNEVAVLRK TRHVNILLFM GYMTKDNLAI VTQWCEGSSL 430 440 450 460 470 480 YYHLHVLDTK FQMFQLIDIA RQTAQGMDYL HAKNIIHRDM KSNNIFLHEG LTVKIGDFGL 490 500 510 520 530 540 ATVKTRWSGS QQVEQLTGSI LWMAPEVIRM QDNNPFSFQS DVYSYGIVLY ELMTGELPYS 550 560 570 580 590 600 HIRDRDQIIF LVGRGGVVPD LSKLYKNCPK AMKRLVADSI KKLRDERPLF PQILSSIELL 610 620 630 QHSLPKINRS ASEPSLHRAA HTEDISSCAL TSTRLPVF

References

[1]	NIH - Xenopus Gene Collection (XGC) project Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Ovary EMBL AAH72748.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC072748 mRNA. Translation: AAH72748.1.
RefSeq	NP_001081475.1. NM_001088006.1.
UniGene	Xl.5697.
3D structure databases
ProteinModelPortal	Q6GQJ4.
SMR	Q6GQJ4. Positions 55-131, 135-186, 333-606.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	397857.
KEGG	xla:397857.
Organism-specific databases
CTD	397857.
Phylogenomic databases
HOVERGEN	HBG001886.
KO	K04366.
Family and domain databases
InterPro	IPR020454. DAG/PE-bd. IPR011009. Kinase-like_dom. IPR002219. Prot_Kinase_C-like_PE/DAG-bd. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR003116. Raf-like_ras-bd. IPR001245. Ser-Thr/Tyr_kinase_cat_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF00130. C1_1. 1 hit. PF07714. Pkinase_Tyr. 1 hit. PF02196. RBD. 1 hit. [Graphical view]
PRINTS	PR00008. DAGPEDOMAIN.
SMART	SM00109. C1. 1 hit. SM00455. RBD. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. PS50898. RBD. 1 hit. PS00479. ZF_DAG_PE_1. 1 hit. PS50081. ZF_DAG_PE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6GQJ4_XENLA

Accession

Primary (citable) accession number: Q6GQJ4

Entry history

Integrated into UniProtKB/TrEMBL:	July 19, 2004
Last sequence update:	July 19, 2004
Last modified:	May 29, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)