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Q6GQE4

- CYC1A_XENLA

UniProt

Q6GQE4 - CYC1A_XENLA

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Protein

Cytochrome c, somatic A

Gene

cycs-a

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity).By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151Heme (covalent)PROSITE-ProRule annotation
Binding sitei18 – 181Heme (covalent)PROSITE-ProRule annotation
Metal bindingi19 – 191Iron (heme axial ligand)PROSITE-ProRule annotation
Metal bindingi81 – 811Iron (heme axial ligand)PROSITE-ProRule annotation

GO - Molecular functioni

  1. electron carrier activity Source: InterPro
  2. heme binding Source: InterPro
  3. iron ion binding Source: InterPro

GO - Biological processi

  1. oxidation-reduction process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c, somatic A
Gene namesi
Name:cycs-a
OrganismiXenopus laevis (African clawed frog)
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-6251722. cyct.

Subcellular locationi

Mitochondrion intermembrane space By similarity
Note: Loosely associated with the inner membrane.By similarity

GO - Cellular componenti

  1. mitochondrion Source: UniProtKB-KW
  2. respiratory chain Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 105104Cytochrome c, somatic APRO_0000266015Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylglycineBy similarity

Post-translational modificationi

Binds 1 heme group per subunit.By similarity

Keywords - PTMi

Acetylation

Structurei

3D structure databases

ProteinModelPortaliQ6GQE4.
SMRiQ6GQE4. Positions 2-104.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome c family.Curated

Phylogenomic databases

HOVERGENiHBG003023.
KOiK08738.

Family and domain databases

Gene3Di1.10.760.10. 1 hit.
InterProiIPR009056. Cyt_c-like_dom.
IPR002327. Cyt_c_1A/1B.
IPR003088. Cyt_c_dom.
[Graphical view]
PANTHERiPTHR11961. PTHR11961. 1 hit.
PfamiPF00034. Cytochrom_C. 1 hit.
[Graphical view]
PRINTSiPR00604. CYTCHRMECIAB.
SUPFAMiSSF46626. SSF46626. 1 hit.
PROSITEiPS51007. CYTC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q6GQE4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGDAEKGKKI FIQKCAQCHT VEKTGKHKTG PNLWGLFGRK TGQAPGFSYT
60 70 80 90 100
DANKSKGIVW GEDTLFEYLE NPKKYIPGTK MIFAGIKKKN ERLDLIAYLK

KSTSE
Length:105
Mass (Da):11,786
Last modified:January 23, 2007 - v3
Checksum:i01DF420C9F306DB7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC072801 mRNA. Translation: AAH72801.1.
RefSeqiNP_001085462.1. NM_001091993.1.
UniGeneiXl.7046.

Genome annotation databases

GeneIDi443888.
KEGGixla:443888.

Cross-referencesi

Web resourcesi

Protein Spotlight

Life shuttle - Issue 76 of November 2006

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC072801 mRNA. Translation: AAH72801.1 .
RefSeqi NP_001085462.1. NM_001091993.1.
UniGenei Xl.7046.

3D structure databases

ProteinModelPortali Q6GQE4.
SMRi Q6GQE4. Positions 2-104.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 443888.
KEGGi xla:443888.

Organism-specific databases

CTDi 443888.
Xenbasei XB-GENE-6251722. cyct.

Phylogenomic databases

HOVERGENi HBG003023.
KOi K08738.

Family and domain databases

Gene3Di 1.10.760.10. 1 hit.
InterProi IPR009056. Cyt_c-like_dom.
IPR002327. Cyt_c_1A/1B.
IPR003088. Cyt_c_dom.
[Graphical view ]
PANTHERi PTHR11961. PTHR11961. 1 hit.
Pfami PF00034. Cytochrom_C. 1 hit.
[Graphical view ]
PRINTSi PR00604. CYTCHRMECIAB.
SUPFAMi SSF46626. SSF46626. 1 hit.
PROSITEi PS51007. CYTC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Spleen.

Entry informationi

Entry nameiCYC1A_XENLA
AccessioniPrimary (citable) accession number: Q6GQE4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 67 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. Protein Spotlight
    Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3