Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Integrin beta

Gene

itgb3

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IntegrinUniRule annotationSAAS annotation

Keywords - Biological processi

Cell adhesionUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Integrin betaUniRule annotation
Gene namesi
Name:itgb3Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Subcellular locationi

  • Membrane UniRule annotation; Single-pass type I membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei717 – 739HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_500427359825 – 788Integrin betaSequence analysisAdd BLAST764

Structurei

3D structure databases

ProteinModelPortaliQ6GP06.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 73PSIInterPro annotationAdd BLAST47
Domaini35 – 459INBInterPro annotationAdd BLAST425
Domaini632 – 716Integrin_B_tailInterPro annotationAdd BLAST85
Domaini740 – 786Integrin_b_cytInterPro annotationAdd BLAST47

Sequence similaritiesi

Belongs to the integrin beta chain family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOVERGENiHBG006190.

Family and domain databases

Gene3Di1.20.5.630. 1 hit.
3.40.50.410. 1 hit.
InterProiIPR013111. EGF_extracell.
IPR033760. Integin_beta_N.
IPR027068. Integrin_beta-3.
IPR015812. Integrin_bsu.
IPR014836. Integrin_bsu_cyt_dom.
IPR012896. Integrin_bsu_tail.
IPR002369. Integrin_bsu_VWA.
IPR032695. Integrin_dom.
IPR016201. PSI.
IPR002035. VWF_A.
[Graphical view]
PANTHERiPTHR10082. PTHR10082. 1 hit.
PTHR10082:SF25. PTHR10082:SF25. 1 hit.
PfamiPF07974. EGF_2. 2 hits.
PF08725. Integrin_b_cyt. 1 hit.
PF07965. Integrin_B_tail. 1 hit.
PF00362. Integrin_beta. 1 hit.
PF17205. PSI_integrin. 1 hit.
[Graphical view]
PIRSFiPIRSF002512. Integrin_B. 1 hit.
PRINTSiPR01186. INTEGRINB.
SMARTiSM00187. INB. 1 hit.
SM01241. Integrin_b_cyt. 1 hit.
SM01242. Integrin_B_tail. 1 hit.
SM00423. PSI. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
SSF69179. SSF69179. 1 hit.
SSF69687. SSF69687. 1 hit.
PROSITEiPS00243. INTEGRIN_BETA. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6GP06-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPDVYIVYT CIVQLLLLTA GTWGASICAT RGVSSCQKCL SVSPQCAWCS
60 70 80 90 100
QEVFGKGAPR CDLKSELLSN GCELKNIEFP VSTVLVAENR PLSVKGSEGD
110 120 130 140 150
TREITQMSPQ KIDLFLRPDD TKVFNLQVRQ VEDYPVDIYY LMDLSYSMKD
160 170 180 190 200
DLIKIQTLGT SLSERMRRLT SNLRIGFGAF VDKPMSPYMF MSPPEVIKNP
210 220 230 240 250
CYEFNTECMP TFGYKHVLTL TEEVLRFNEE VQKQKVSRNR DSPEGGFDAV
260 270 280 290 300
LQAAVCDEKI GWRNESSHLL VFTTDARTHI ALDGRLAGIV QPNDGKCHLD
310 320 330 340 350
LNNDYAASTT LDYPSIGLMT EKLSDKNINL VFAVTNEVLS LYTKYSELIP
360 370 380 390 400
GTTVGVLSQD SGNVIQLIEN SYEKIRSKVE LEVRDLPEEL SLSFSASCQN
410 420 430 440 450
DELTPGLKSC TGLKIGDTVS FSIEAKVREC PSVRQKTFTI KPVGFKDSLT
460 470 480 490 500
VTVHFQCNCA CQENDQPNST LCNHGNGTLS CGICQCNPGW LGPYCECSEE
510 520 530 540 550
EYNPSQQDRC SSKEGAPVCS RRGDCVCGQC VCRASDLGKV WGKYCECDDF
560 570 580 590 600
SCLRYKGEMC SGHGQCNCGD CICESDWTGD YCNCTTRTDT CMSSSGLLCS
610 620 630 640 650
GRGQCVCGKC ECTQPGSYGD TCEKCPTCPD ACTFKKGCVE CKKFERGPWF
660 670 680 690 700
EDSSCKQICR DEIESVTELV DNGKNAVNCT YKDENDCVVR FQYHEDASGK
710 720 730 740 750
SVLYVINEAE CPQGPDILVV LMSVMGAILL IGLVALLIWK LLITIHDRRE
760 770 780
FAKFEEERAK AKWDTAHNPL YKGATSTFTN ITYRGNTE
Length:788
Mass (Da):87,453
Last modified:July 19, 2004 - v1
Checksum:i1D04A71C6B6AB610
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC073343 mRNA. Translation: AAH73343.1.
UniGeneiXl.29245.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC073343 mRNA. Translation: AAH73343.1.
UniGeneiXl.29245.

3D structure databases

ProteinModelPortaliQ6GP06.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG006190.

Family and domain databases

Gene3Di1.20.5.630. 1 hit.
3.40.50.410. 1 hit.
InterProiIPR013111. EGF_extracell.
IPR033760. Integin_beta_N.
IPR027068. Integrin_beta-3.
IPR015812. Integrin_bsu.
IPR014836. Integrin_bsu_cyt_dom.
IPR012896. Integrin_bsu_tail.
IPR002369. Integrin_bsu_VWA.
IPR032695. Integrin_dom.
IPR016201. PSI.
IPR002035. VWF_A.
[Graphical view]
PANTHERiPTHR10082. PTHR10082. 1 hit.
PTHR10082:SF25. PTHR10082:SF25. 1 hit.
PfamiPF07974. EGF_2. 2 hits.
PF08725. Integrin_b_cyt. 1 hit.
PF07965. Integrin_B_tail. 1 hit.
PF00362. Integrin_beta. 1 hit.
PF17205. PSI_integrin. 1 hit.
[Graphical view]
PIRSFiPIRSF002512. Integrin_B. 1 hit.
PRINTSiPR01186. INTEGRINB.
SMARTiSM00187. INB. 1 hit.
SM01241. Integrin_b_cyt. 1 hit.
SM01242. Integrin_B_tail. 1 hit.
SM00423. PSI. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
SSF69179. SSF69179. 1 hit.
SSF69687. SSF69687. 1 hit.
PROSITEiPS00243. INTEGRIN_BETA. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6GP06_XENLA
AccessioniPrimary (citable) accession number: Q6GP06
Entry historyi
Integrated into UniProtKB/TrEMBL: July 19, 2004
Last sequence update: July 19, 2004
Last modified: November 30, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.