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Protein
Submitted name:

IGH@ protein

Gene

IGH@

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei93N-acetyl-D-glucosamineCombined sources1

Names & Taxonomyi

Protein namesi
Submitted name:
IGH@ proteinImported
Gene namesi
Name:IGH@Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500427357920 – 465Sequence analysisAdd BLAST446

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi41 ↔ 114Combined sources
Disulfide bondi162 ↔ 218Combined sources
Disulfide bondi385 ↔ 443Combined sources

Proteomic databases

PeptideAtlasiQ6GMX6.
PRIDEiQ6GMX6.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1BEYX-ray3.25H20-233[»]
1ZA6X-ray2.80B/D/F/H20-465[»]
2JIXX-ray3.20D/F/H20-236[»]
3B2UX-ray2.58C/F/H/J/N/Q/T/W20-237[»]
3B2VX-ray3.30H20-237[»]
3D0LX-ray2.35B20-240[»]
3ZL4X-ray1.95H20-238[»]
4D9LX-ray2.48H/I/J/K20-237[»]
4FQQX-ray2.42B/D/F/H20-242[»]
4LKXX-ray1.92A20-243[»]
4NPYX-ray1.80A/L31-238[»]
B/H20-238[»]
4QHKX-ray3.49I/K/M/O20-242[»]
4QHLX-ray3.15A/C20-242[»]
4QHMX-ray3.23A/C/E/G20-242[»]
4QHNX-ray3.00A20-242[»]
ProteinModelPortaliQ6GMX6.
SMRiQ6GMX6.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ6GMX6.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 114Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST101
Domaini141 – 234Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST94
Domaini256 – 355Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST100
Domaini364 – 460Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST97

Keywords - Domaini

Immunoglobulin domainSAAS annotation, SignalSequence analysis

Phylogenomic databases

HOVERGENiHBG005814.

Family and domain databases

Gene3Di2.60.40.10. 4 hits.
InterProiView protein in InterPro
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
PfamiView protein in Pfam
PF07654. C1-set. 3 hits.
PF07686. V-set. 1 hit.
SMARTiView protein in SMART
SM00409. IG. 2 hits.
SM00407. IGc1. 3 hits.
SM00406. IGv. 1 hit.
SUPFAMiSSF48726. SSF48726. 4 hits.
PROSITEiView protein in PROSITE
PS50835. IG_LIKE. 4 hits.
PS00290. IG_MHC. 2 hits.

Sequencei

Sequence statusi: Complete.

Q6GMX6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKHLWFFLLL VAAPRWVLSQ VQLQESGPGL VKPSETLSLT CTVSGGSISG
60 70 80 90 100
YYWSWIRQPA GKGLEWIGRI YTSGSTNYNP SLKSRVTMSV DTSKNQFSLK
110 120 130 140 150
LSSVTAADTA VYYCARGRFT YFDYWGQGTL VTVSSASTKG PSVFPLAPSS
160 170 180 190 200
KSTSGGTAAL GCLVKDYFPE PVTVSWNSGA LTSGVHTFPA VLQSSGLYSL
210 220 230 240 250
SSVVTVPSSS LGTQTYICNV NHKPSNTKVD KKVEPKSCDK THTCPPCPAP
260 270 280 290 300
ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV
310 320 330 340 350
EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI
360 370 380 390 400
EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE
410 420 430 440 450
SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL
460
HNHYTQKSLS LSPGK
Length:465
Mass (Da):51,083
Last modified:July 19, 2004 - v1
Checksum:iB3A9B7D0FDB1386E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC073766 mRNA. Translation: AAH73766.1.
UniGeneiHs.510635.

Similar proteinsi

Entry informationi

Entry nameiQ6GMX6_HUMAN
AccessioniPrimary (citable) accession number: Q6GMX6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 19, 2004
Last sequence update: July 19, 2004
Last modified: August 30, 2017
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources