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Q6GMV1 (ALG1L_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative glycosyltransferase ALG1-like

EC=2.4.1.-
Gene names
Name:ALG1L
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length187 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Putative glycosyltransferase By similarity.

Sequence similarities

Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 33 subfamily.

Ontologies

Keywords
   Coding sequence diversityPolymorphism
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functiontransferase activity, transferring glycosyl groups

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 187187Putative glycosyltransferase ALG1-like
PRO_0000326037

Natural variations

Natural variant1351N → D. Ref.3
Corresponds to variant rs3828357 [ dbSNP | Ensembl ].
VAR_039962
Natural variant1591I → T.
Corresponds to variant rs3811679 [ dbSNP | Ensembl ].
VAR_039963
Natural variant1841G → S.
Corresponds to variant rs3187686 [ dbSNP | Ensembl ].
VAR_039964

Sequences

Sequence LengthMass (Da)Tools
Q6GMV1 [UniParc].

Last modified November 24, 2009. Version 2.
Checksum: D8346DBD88A66CCF

FASTA18721,132
        10         20         30         40         50         60 
MERSAFMELD AGSRLVMHLR EWPALLVSST GWTEFEQLTL DGHNLPSLVC VITGSVDLGV 

        70         80         90        100        110        120 
CLHMSSSGLD LPMKVVDMFG CCLPVCAVNF KCLHELVKHE ENGLVFEDSE ELAALQMLFS 

       130        140        150        160        170        180 
NFPDPAGKLN QFWKNLRESQ QLRWDESWVQ TVLPLVMDIQ LLGQRLKPRD PCCPSRSFFS 


ESQGKPF 

« Hide

References

[1]"The DNA sequence, annotation and analysis of human chromosome 3."
Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J. expand/collapse author list , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ASP-135.
Tissue: Brain.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH471052 Genomic DNA. Translation: EAW79378.1.
CH471052 Genomic DNA. Translation: EAW79380.1.
BC073816 mRNA. Translation: AAH73816.1.
CCDSCCDS33840.1.
RefSeqNP_001015050.2. NM_001015050.2.
NP_001182152.1. NM_001195223.1.
UniGeneHs.591299.

3D structure databases

ProteinModelPortalQ6GMV1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid128347. 1 interaction.

Protein family/group databases

CAZyGT33. Glycosyltransferase Family 33.

Polymorphism databases

DMDM269849540.

Proteomic databases

PaxDbQ6GMV1.
PRIDEQ6GMV1.

Protocols and materials databases

DNASU200810.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000340333; ENSP00000340009; ENSG00000189366.
GeneID200810.
KEGGhsa:200810.
UCSCuc003eig.2. human.

Organism-specific databases

CTD200810.
GeneCardsGC03M125648.
HGNCHGNC:33721. ALG1L.
HPAHPA036108.
neXtProtNX_Q6GMV1.
PharmGKBPA165696816.
GenAtlasSearch...

Phylogenomic databases

eggNOGCOG0438.
HOGENOMHOG000172312.
InParanoidQ6GMV1.
OMAREWPALL.
OrthoDBEOG70W3DB.
PhylomeDBQ6GMV1.

Gene expression databases

BgeeQ6GMV1.
GenevestigatorQ6GMV1.

Family and domain databases

InterProIPR026051. ALG1-like.
[Graphical view]
PANTHERPTHR13036. PTHR13036. 1 hit.
ProtoNetSearch...

Other

GenomeRNAi200810.
NextBio89978.
PROQ6GMV1.

Entry information

Entry nameALG1L_HUMAN
AccessionPrimary (citable) accession number: Q6GMV1
Secondary accession number(s): D3DNA5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: November 24, 2009
Last modified: July 9, 2014
This is version 75 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 3

Human chromosome 3: entries, gene names and cross-references to MIM