Reviewed, UniProtKB/Swiss-Prot Q6GMV1 (ALG1L_HUMAN)

Names and origin

Protein names

Recommended name:
    Putative glycosyltransferase ALG1-like
    EC=2.4.1.-

Gene names

Name:

ALG1L

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	187 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Putative glycosyltransferase By similarity.
Sequence similarities	Belongs to the glycosyltransferase 1 family.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	transferase activity, transferring glycosyl groups Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 187	187	Putative glycosyltransferase ALG1-like		PRO_0000326037
Natural variations
	Natural variant	135	1	N → D: dbSNP rs3828357.		VAR_039962
	Natural variant	159	1	I → T: dbSNP rs3811679.		VAR_039963
	Natural variant	184	1	G → S: dbSNP rs3187686.		VAR_039964

Sequences

	Sequence		Length	Mass (Da)
	Q6GMV1-1 [UniParc]. Last modified November 24, 2009. Version 2. Checksum: D8346DBD88A66CCF	FASTA	187	21,132
	10 20 30 40 50 60 MERSAFMELD AGSRLVMHLR EWPALLVSST GWTEFEQLTL DGHNLPSLVC VITGSVDLGV 70 80 90 100 110 120 CLHMSSSGLD LPMKVVDMFG CCLPVCAVNF KCLHELVKHE ENGLVFEDSE ELAALQMLFS 130 140 150 160 170 180 NFPDPAGKLN QFWKNLRESQ QLRWDESWVQ TVLPLVMDIQ LLGQRLKPRD PCCPSRSFFS ESQGKPF

References

[1]

"The DNA sequence, annotation and analysis of human chromosome 3." Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J. , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A. Nature 440:1194-1198(2006) [PubMed: 16641997] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ASP-135. Tissue: Brain.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BC073816 mRNA. Translation: AAH73816.1.
IPI	IPI00145612.
RefSeq	NP_001015050.1.
UniGene	Hs.591299
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GT33. Glycosyltransferase Family 33.
Proteomic databases
PRIDE	Q6GMV1.
Genome annotation databases
Ensembl	ENST00000340333; ENSP00000340009; ENSG00000189366; Homo sapiens. [Genome view] ENST00000437882; ENSP00000408369; ENSG00000189366; Homo sapiens. [Genome view]
GeneID	200810.
KEGG	hsa:200810.
UCSC	uc003eig.1. human.
Organism-specific databases
CTD	200810.
GeneCards	GC03M127130. GC11P067271.
HGNC	HGNC:33721. ALG1L.
GenAtlas	Search...
Gene expression databases
Genevestigator	Q6GMV1.
Family and domain databases
ProtoNet	Search...
Other Resources
NextBio	89978.

Entry information

Entry name

ALG1L_HUMAN

Accession

Primary (citable) accession number: Q6GMV1

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	November 24, 2009
Last modified:	November 24, 2009
This is version 39 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.