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Q6GMN6

- Q6GMN6_RAT

UniProt

Q6GMN6 - Q6GMN6_RAT

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Protein
Submitted name:

Carnitine O-octanoyltransferase

Gene

Crot

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. carnitine O-octanoyltransferase activity Source: Ensembl

GO - Biological processi

  1. carnitine metabolic process Source: Ensembl
  2. coenzyme A metabolic process Source: Ensembl
  3. fatty acid beta-oxidation Source: Ensembl
  4. fatty acid transport Source: Ensembl
  5. generation of precursor metabolites and energy Source: Ensembl
  6. medium-chain fatty acid metabolic process Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotation, Transferase

Enzyme and pathway databases

ReactomeiREACT_239598. Beta-oxidation of pristanoyl-CoA.

Names & Taxonomyi

Protein namesi
Submitted name:
Carnitine O-octanoyltransferaseImported
Submitted name:
Carnitine O-octanoyltransferase, isoform CRA_aImported
Submitted name:
Peroxisomal carnitine O-octanoyltransferaseImported
Gene namesi
Name:CrotImported
ORF Names:rCG_41076Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 4

Organism-specific databases

RGDi70908. Crot.

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: Ensembl
  2. peroxisome Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ6GMN6.

Family & Domainsi

Sequence similaritiesi

Belongs to the carnitine/choline acetyltransferase family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000119220.
HOVERGENiHBG104403.
KOiK05940.
OMAiDSIMNYF.
OrthoDBiEOG7BGHKN.
TreeFamiTF313836.

Family and domain databases

InterProiIPR000542. Carn_acyl_trans.
[Graphical view]
PANTHERiPTHR22589. PTHR22589. 1 hit.
PfamiPF00755. Carn_acyltransf. 1 hit.
[Graphical view]
PROSITEiPS00439. ACYLTRANSF_C_1. 1 hit.
PS00440. ACYLTRANSF_C_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6GMN6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MENQLAKSIE ERTFQYQDSL PPLPVPSLEE SLKKYLESVK PFANEDEYKK
60 70 80 90 100
TEEIVQKFQD GVGKTLHQKL LERAKGKRNW LEEWWLNVAY LDVRIPSQLN
110 120 130 140 150
VNFVGPSPHF EHYWPAREGT QLERGSILLW HNLNYWQLLR REKLPVHKSG
160 170 180 190 200
NTPLDMNQFR MLFSTCKVPG ITRDSIMNYF KTESEGHCPT HIAVLCRGRA
210 220 230 240 250
FVFDVLHDGC LITPPELLRQ LTYIYQKCWN EPVGPSIAAL TSEERTRWAK
260 270 280 290 300
AREYLIGLDP ENLTLLEKIQ SSLFVYSIED TSPHATPENF SQVFEMLLGG
310 320 330 340 350
DPAVRWGDKS YNLISFANGI FGCSCDHAPY DAMVMVNIAH YVDEKLLETE
360 370 380 390 400
GRWKGSEKVR DIPLPEELAF TVDEKILNDV YQAKAQHLKA ASDLQIAAST
410 420 430 440 450
FTSFGKKLTK KEALHPDTFI QLALQLAYYR LHGRPGCCYE TAMTRYFYHG
460 470 480 490 500
RTETVRSCTV EAVRWCQSMQ DPSASLLERQ QKMLDAFAKH NKMMRDCSHG
510 520 530 540 550
KGFDRHLLGL LLIAKEEGLP VPELFEDPLF SRSGGGGNFV LSTSLVGYLR
560 570 580 590 600
IQGVVVPMVH NGYGFFYHIR DDRFVVTCSS WRSCLETDAE KLVEMIFHAF
610
HDMIHLMNTA HL
Length:612
Mass (Da):70,288
Last modified:July 19, 2004 - v1
Checksum:i7860FC59BD683CB4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06029235 Genomic DNA. No translation available.
AABR06029236 Genomic DNA. No translation available.
AABR06029237 Genomic DNA. No translation available.
BC074004 mRNA. Translation: AAH74004.1.
CH474013 Genomic DNA. Translation: EDL84313.1.
CH474013 Genomic DNA. Translation: EDL84314.1.
RefSeqiXP_006236067.1. XM_006236005.2.
UniGeneiRn.4896.

Genome annotation databases

EnsembliENSRNOT00000067462; ENSRNOP00000063856; ENSRNOG00000006779.
GeneIDi83842.
KEGGirno:83842.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06029235 Genomic DNA. No translation available.
AABR06029236 Genomic DNA. No translation available.
AABR06029237 Genomic DNA. No translation available.
BC074004 mRNA. Translation: AAH74004.1 .
CH474013 Genomic DNA. Translation: EDL84313.1 .
CH474013 Genomic DNA. Translation: EDL84314.1 .
RefSeqi XP_006236067.1. XM_006236005.2.
UniGenei Rn.4896.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000067462 ; ENSRNOP00000063856 ; ENSRNOG00000006779 .
GeneIDi 83842.
KEGGi rno:83842.

Organism-specific databases

CTDi 54677.
RGDi 70908. Crot.

Phylogenomic databases

GeneTreei ENSGT00760000119220.
HOVERGENi HBG104403.
KOi K05940.
OMAi DSIMNYF.
OrthoDBi EOG7BGHKN.
TreeFami TF313836.

Enzyme and pathway databases

Reactomei REACT_239598. Beta-oxidation of pristanoyl-CoA.

Miscellaneous databases

PROi Q6GMN6.

Gene expression databases

Genevestigatori Q6GMN6.

Family and domain databases

InterProi IPR000542. Carn_acyl_trans.
[Graphical view ]
PANTHERi PTHR22589. PTHR22589. 1 hit.
Pfami PF00755. Carn_acyltransf. 1 hit.
[Graphical view ]
PROSITEi PS00439. ACYLTRANSF_C_1. 1 hit.
PS00440. ACYLTRANSF_C_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: LungImported.
  2. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  5. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiQ6GMN6_RAT
AccessioniPrimary (citable) accession number: Q6GMN6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 19, 2004
Last sequence update: July 19, 2004
Last modified: November 26, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3