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Q6GM06 (OTU6B_XENLA) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
OTU domain-containing protein 6B

EC=3.4.19.12
Gene names
Name:otud6b
OrganismXenopus laevis (African clawed frog)
Taxonomic identifier8355 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Protein attributes

Sequence length294 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).

Sequence similarities

Contains 1 OTU domain.

Ontologies

Keywords
   Biological processUbl conjugation pathway
   Molecular functionHydrolase
Protease
Thiol protease
Gene Ontology (GO)
   Biological_processproteolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functioncysteine-type peptidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 294294OTU domain-containing protein 6B
PRO_0000076283

Regions

Domain150 – 287138OTU
Region155 – 1617Cys-loop By similarity
Region222 – 23211Variable-loop By similarity
Region270 – 28011His-loop By similarity

Sites

Active site1581 By similarity
Active site1611Nucleophile By similarity
Active site2801 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6GM06 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 48293B8CD6D4E7F0

FASTA29433,432
        10         20         30         40         50         60 
MDVAEENSEE ALLIKQQRKE KKEVQAKIQC MKNSVPKNDK KRRKQMTEDI AKLEAEVEAR 

        70         80         90        100        110        120 
HKEELEALAQ KPTEPTQVSS ITNGVTSLDL GSEEPVQQPR VSKAQKRREK KAAQEKERDD 

       130        140        150        160        170        180 
RIAEAEIANL SGARHLESQK LAQILAEREL QIRQIPSDGH CMYRAIEHQL NEQGNSLTVA 

       190        200        210        220        230        240 
NLRSQTADYM QKRAEDFLPF LTNSSTGDMY TQEEFQKYCT DIVNTPAWGG QLELRALSHI 

       250        260        270        280        290 
LKTPIEVIQA ESLPIVIGEE YSNKPITLVY MRHAYGLGEH YNSVEQLDTS TENS 

« Hide

References

[1]NIH - Xenopus Gene Collection (XGC) project
Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Eye.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC074286 mRNA. Translation: AAH74286.1.
RefSeqNP_001086171.1. NM_001092702.1.
UniGeneXl.15114.

3D structure databases

ProteinModelPortalQ6GM06.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID444600.
KEGGxla:444600.

Organism-specific databases

CTD51633.

Phylogenomic databases

HOVERGENHBG080227.

Family and domain databases

InterProIPR003323. OTU.
[Graphical view]
PfamPF02338. OTU. 1 hit.
[Graphical view]
PROSITEPS50802. OTU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameOTU6B_XENLA
AccessionPrimary (citable) accession number: Q6GM06
Entry history
Integrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: July 19, 2004
Last modified: November 13, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families