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Reviewed, UniProtKB/Swiss-Prot Q6GL12 (SPS1_XENTR)

Last modified February 9, 2010. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Selenide, water dikinase 1
    EC=2.7.9.3
Alternative name(s):
    Selenophosphate synthetase 1
    Selenium donor protein 1
Gene names
Name: sephs1
OrganismXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifier8364 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraMesobatrachiaPipoideaPipidaeXenopodinaeXenopusSilurana

Protein attributes

Sequence length392 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Function

Synthesizes selenophosphate from selenide and ATP By similarity.

Catalytic activity

ATP + selenide + H2O = AMP + selenophosphate + phosphate.

Sequence similarities

Belongs to the selenophosphate synthetase 1 family. Class II subfamily.

Caution

The conserved active site Cys (or selenocysteine) residue in position 29 is replaced by a Thr. However, as function in selenoprotein synthesis is probable, it is possible Cys-31 is the active site.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 392392Selenide, water dikinase 1
PRO_0000312510

Regions

Nucleotide binding268 – 2747ATP Potential

Sites

Active site311 Potential
Site321Important for catalytic activity By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6GL12-1 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: DB276A3FEBE8C31E

FASTA39242,818
        10         20         30         40         50         60 
MSVRESFNPE SYELDKSFRL TRFAELKGTG CKVPQDVLQK LLESLQENHF QEDEQFLGAV 

        70         80         90        100        110        120 
MPRLGIGMDT CVIPLRHGGL SLVQTTDYIY PIVDDPYMMG RIACANVLSD LYAMGVTECD 

       130        140        150        160        170        180 
NMLMLLGVSN KLTDRERDKV MPLIIQGFKD AAEEAGTSVT GGQTVLNPWV VLGGVATTVC 

       190        200        210        220        230        240 
QPNEFIMPDN AVPGDVLVLT KPLGTQVAVA VHQWLDIPEK WNKIKLVVTQ EDVELAYQEA 

       250        260        270        280        290        300 
MMNMARLNRT AAGLMHTFNA HAATDITGFG ILGHAQNLAK QQRNEVSFVI HNLPVLAKMA 

       310        320        330        340        350        360 
AVSKACGNMF GLMHGSCPET SGGLLICLPR EQAARFCAEI KSPKYGEGHQ AWIIGIVEKG 

       370        380        390 
NRTARIIDKP RIIEVAPQVA SQNVNPTPGA TS 

« Hide

References

[1]NIH - Xenopus Gene Collection (XGC) project
Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Embryo.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC074707 mRNA. Translation: AAH74707.1.
RefSeqNP_001006902.1.
UniGeneStr.18431

3D structure databases

SMRQ6GL12. Positions 16-363.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ6GL12.

Genome annotation databases

EnsemblENSXETT00000019994; ENSXETP00000019994; ENSXETG00000009116; Xenopus tropicalis. [Genome view]
GeneID448749.
KEGGxtr:448749.

Organism-specific databases

CTD448749.
XenbaseXB-FEAT-986439. sephs1.

Phylogenomic databases

eggNOGveNOG09639.
HOGENOMHBG383791.
HOVERGENQ6GL12.
InParanoidQ6GL12.

Enzyme and pathway databases

BRENDA2.7.9.3. 279072.

Family and domain databases

InterProIPR000728. AIR_synth.
IPR010918. AIR_synth_C.
IPR016188. PurM_N-like.
IPR004536. SelD.
[Graphical view]
PfamPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
PIRSFPIRSF036407. Selenphspht_syn. 1 hit.
TIGRFAMsTIGR00476. selD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSPS1_XENTR
AccessionPrimary (citable) accession number: Q6GL12
Entry history
Integrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: July 19, 2004
Last modified: February 9, 2010
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectXenopus annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents