Q6GJI2 (Q6GJI2_STAAR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Ribosomal RNA small subunit methyltransferase I HAMAP MF_01877
EC=2.1.1.198 HAMAP MF_01877

Alternative name(s):
16S rRNA 2'-O-ribose C1402 methyltransferase HAMAP MF_01877
rRNA (cytidine-2'-O-)-methyltransferase RsmI HAMAP MF_01877

Gene names

Name:	rsmI HAMAP MF_01877
Ordered Locus Names:	SAR0490

Organism

Staphylococcus aureus (strain MRSA252) [Complete proteome] [HAMAP]

Taxonomic identifier

282458 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	279 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA By similarity. HAMAP MF_01877
Catalytic activity	S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytosine(1402) in 16S rRNA. HAMAP MF_01877
Subcellular location	Cytoplasm By similarity HAMAP MF_01877.
Sequence similarities	Belongs to the methyltransferase superfamily. RsmI family. HAMAP MF_01877

Ontologies

Keywords
Biological process	rRNA processing HAMAP MF_01877
Cellular component	Cytoplasm HAMAP MF_01877
Ligand	S-adenosyl-L-methionine HAMAP MF_01877
Molecular function	Methyltransferase HAMAP MF_01877 EMBL CAG39512.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	enzyme-directed rRNA 2'-O-methylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA (cytosine-2'-O-)-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6GJI2 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: 23DA75B31B97C4E6	FASTA	279	31,302
	10 20 30 40 50 60 MAVLYLVGTP IGNLADITYR AVDVLKRVDM IACEDTRVTS KLCNHYDIPT PLKSYHEHNK 70 80 90 100 110 120 DKQTAFIIEQ LELGLDVALV SDAGLPLISD PGYELVVAAR EANIKVETVP GPNAGLTALM 130 140 150 160 170 180 ASGLPSYVYT FLGFLPRKEK EKSAVLEQRM HENSTLIIYE SPHRVTDTLK TIAKIDATRQ 190 200 210 220 230 240 VSLGRELTKK FEQIVTDDVT QLQALIQQGD VPLKGEFVIL IEGAKANNEI SWFDDLSINE 250 260 270 HVDHYIQTSQ MKPKQAIKKV AEERQLKTNE VYNIYHQIN

References

[1]

"Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance." Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J., Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A., Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C., Clark L., Corton C. , Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z., Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N., Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M., Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J. Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004) [PubMed: 15213324] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX571856 Genomic DNA. Translation: CAG39512.1.
RefSeq	YP_039940.1. NC_002952.2.
3D structure databases
ProteinModelPortal	Q6GJI2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6GJI2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000021117; EBSTAP00000020453; EBSTAG00000021116.
GeneID	2859459.
GenomeReviews	Gene locus SAR0490 in contig BX571856_GR.
KEGG	sar:SAR0490.
PATRIC	19544500. VBIStaAur71814_0496.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0313.
GeneTree	EBGT00050000024705.
HOGENOM	HBG529058.
OMA	GREMTKI.
PhylomeDB	Q6GJI2.
ProtClustDB	CLSK884689.
Enzyme and pathway databases
BioCyc	SAUR282458:SAR0490-MONOMER.
Family and domain databases
HAMAP	MF_01877. 16SrRNA_methyltr_I. [Tree]
InterPro	IPR000878. 4pyrrol_Mease. IPR014777. 4pyrrole_Mease_sub1. IPR008189. rRNA_ssu_MeTfrase_I. IPR018063. SAM_MeTrfase_RsmI_CS. [Graphical view]
Gene3D	G3DSA:3.40.1010.10. 4pyrrole_Mease_sub1. 1 hit.
KO	K07056.
PANTHER	PTHR21091:SF18. PTHR21091:SF18. 1 hit.
Pfam	PF00590. TP_methylase. 1 hit. [Graphical view]
PIRSF	PIRSF005917. MTase_YraL. 1 hit.
SUPFAM	SSF53790. Cor/por_Metransf. 1 hit.
TIGRFAMs	TIGR00096. TIGR00096. 1 hit.
PROSITE	PS01296. RSMI. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6GJI2_STAAR

Accession

Primary (citable) accession number: Q6GJI2

Entry history

Integrated into UniProtKB/TrEMBL:	July 19, 2004
Last sequence update:	July 19, 2004
Last modified:	December 14, 2011
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)