Q6GJ34 (TAGA_STAAR) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 46.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Putative N-acetylmannosaminyltransferase EC=2.4.1.187 Alternative name(s): Major teichoic acid biosynthesis protein A N-acetylglucosaminyldiphospho-undecaprenol N-acetyl-beta-D-mannosaminyltransferase UDP-N-acetylmannosamine transferase | ||||
| Gene names |
| ||||
| Organism | Staphylococcus aureus (strain MRSA252) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 282458 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Staphylococcus |
Protein attributes
| Sequence length | 254 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, a key lipid intermediate in the de novo synthesis of teichoic acid Potential. |
| Catalytic activity | UDP-N-acetyl-D-mannosamine + N-acetyl-D-glucosaminyldiphosphoundecaprenol = UDP + N-acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol. |
| Pathway | Cell wall biogenesis; poly(glycerol phosphate) teichoic acid biosynthesis. |
| Subcellular location | |
| Sequence similarities | Belongs to the glycosyltransferase 26 family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Cell shape Cell wall biogenesis/degradation Teichoic acid biosynthesis |
| Cellular component | Secreted |
| Molecular function | Glycosyltransferase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shapeInferred from electronic annotation. Source: UniProtKB-KW teichoic acid biosynthetic processInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cell wall Inferred from electronic annotation. Source: UniProtKB-SubCell extracellular regionInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 254 | 254 | Putative N-acetylmannosaminyltransferase | PRO_0000208444 | |||
Sequences
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References
| [1] | "Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance." Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J., Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A., Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C., Clark L., Corton C. Parkhill J.Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004) [PubMed: 15213324] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MRSA252. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BX571856 Genomic DNA. Translation: CAG39663.1. |
| RefSeq | YP_040088.1. NC_002952.2. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q6GJ34. |
Protein family/group databases | |
| CAZy | GT26. Glycosyltransferase Family 26. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBSTAT00000020352; EBSTAP00000019688; EBSTAG00000020351. |
| GeneID | 2859514. |
| GenomeReviews | Gene locus SAR0646 in contig BX571856_GR. |
| KEGG | sar:SAR0646. |
| PATRIC | 19544841. VBIStaAur71814_0653. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG1922. |
| GeneTree | EBGT00050000025549. |
| HOGENOM | HBG685240. |
| OMA | ENFIQNN. |
| ProtClustDB | CLSK884777. |
Enzyme and pathway databases | |
| BioCyc | SAUR282458:SAR0646-MONOMER. |
Family and domain databases | |
| InterPro | IPR004629. WecB_TagA_CpsF. [Graphical view] |
| KO | K05946. |
| Pfam | PF03808. Glyco_tran_WecB. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR00696. WecB_tagA_cpsF. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | TAGA_STAAR | ||||||||
| Accession | Primary (citable) accession number: Q6GJ34 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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