Q6GIM2 (Q6GIM2_STAAR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative malolactic enzyme EMBL CAG39833.1

Gene names

Ordered Locus Names:

SAR0824

Organism

Staphylococcus aureus (strain MRSA252) [Complete proteome] [HAMAP]

Taxonomic identifier

282458 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	544 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the malic enzymes family. RuleBase RU003427

Ontologies

Keywords
Ligand	Metal-binding RuleBase RU003427
Molecular function	Oxidoreductase RuleBase RU003427
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	malate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	NAD binding Inferred from electronic annotation. Source: InterPro malate dehydrogenase (oxaloacetate-decarboxylating) activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6GIM2 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: B070B14050634C3E	FASTA	544	60,596
	10 20 30 40 50 60 MKGIELLNNP FLNKGTAFTN EERKQLGLEG LLPANVRTLE QQAEQCYEQF KAKQTDFEKR 70 80 90 100 110 120 LFLMAIFNRN RTLFYKLTSE HLVEFMPIIY DPVIAQSIEQ YNENFSRPQD AVFLSVDRQD 130 140 150 160 170 180 QIEQELRNVA NGRDIRLIVV TDAEGILGIG DWGVDGVDIA IGKLIVYTAA AGINPAQVLP 190 200 210 220 230 240 VSLDVGTNNE QLLNDELYLG NRHKRVDDET YYTFVDKFVS AVRKEYPNAL LHWEDFGRGH 250 260 270 280 290 300 AKNILDKYED TLPTFNDDIQ GTGIVTLAGV LGALNISKVD YTNQTFLVYG GGTAGMGITN 310 320 330 340 350 360 ILKDELIKQD VSEDKANQHF YIMDKQGLLF DDMDDLTEAQ QVFAKNRNEF SNTVNWKNLK 370 380 390 400 410 420 EVIENIKPTV LIGTSTQTGA FTEDAVKEML KHTERPMIFP LSNPTKLAEA TAQDLLKWTN 430 440 450 460 470 480 GKALIGTGIP YNDIEYNGVN YSIGQANNAL MYPGLGLGLI ASKAKKVNQQ ILSAASHALG 490 500 510 520 530 540 GMVNPDEPGA AVLPPVEKIH QCSRAIAKAV AQSVIDQGLN AETIDDIDEA IEAEIWYPEY KSYI

References

[1]

"Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance." Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J., Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A., Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C., Clark L., Corton C. , Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z., Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N., Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M., Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J. Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004) [PubMed: 15213324] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX571856 Genomic DNA. Translation: CAG39833.1.
RefSeq	YP_040250.1. NC_002952.2.
3D structure databases
ProteinModelPortal	Q6GIM2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6GIM2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000021213; EBSTAP00000020549; EBSTAG00000021212.
GeneID	2860729.
GenomeReviews	Gene locus SAR0824 in contig BX571856_GR.
KEGG	sar:SAR0824.
PATRIC	19545185. VBIStaAur71814_0825.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0281.
GeneTree	EBGT00050000024440.
HOGENOM	HBG289821.
OMA	QDNNETL.
ProtClustDB	PRK13529.
Enzyme and pathway databases
BioCyc	SAUR282458:SAR0824-MONOMER.
Family and domain databases
InterPro	IPR015884. Malic_enzyme_CS. IPR012301. Malic_N. IPR012302. Malic_NAD-bd. IPR001891. Malic_OxRdtase. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.10380. G3DSA:3.40.50.10380. 1 hit. G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00027.
Pfam	PF00390. malic. 1 hit. PF03949. Malic_M. 1 hit. [Graphical view]
PIRSF	PIRSF000106. ME. 1 hit.
PRINTS	PR00072. MALOXRDTASE.
SMART	SM00919. Malic_M. 1 hit. [Graphical view]
PROSITE	PS00331. MALIC_ENZYMES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6GIM2_STAAR

Accession

Primary (citable) accession number: Q6GIM2

Entry history

Integrated into UniProtKB/TrEMBL:	July 19, 2004
Last sequence update:	July 19, 2004
Last modified:	December 14, 2011
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)