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Q6GIG7

- 2NPD_STAAR

UniProt

Q6GIG7 - 2NPD_STAAR

Protein

Probable nitronate monooxygenase

Gene

SAR0883

Organism
Staphylococcus aureus (strain MRSA252)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 69 (01 Oct 2014)
      Sequence version 1 (19 Jul 2004)
      Previous versions | rss
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    Functioni

    Catalyzes the oxidation of alkyl nitronates to produce the corresponding carbonyl compounds and nitrites.By similarity

    Catalytic activityi

    Ethylnitronate + O2 = acetaldehyde + nitrite + other products.

    Cofactori

    Binds 1 FMN per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei182 – 1821Proton acceptorSequence Analysis
    Binding sitei182 – 1821SubstrateBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi21 – 233FMNBy similarity
    Nucleotide bindingi216 – 2183FMNBy similarity
    Nucleotide bindingi239 – 2402FMNBy similarity

    GO - Molecular functioni

    1. nitronate monooxygenase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Monooxygenase, Oxidoreductase

    Keywords - Ligandi

    Flavoprotein, FMN

    Enzyme and pathway databases

    BioCyciSAUR282458:GJA5-884-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable nitronate monooxygenase (EC:1.13.12.16)
    Alternative name(s):
    Nitroalkane oxidase
    Gene namesi
    Ordered Locus Names:SAR0883
    OrganismiStaphylococcus aureus (strain MRSA252)
    Taxonomic identifieri282458 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000000596: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 355355Probable nitronate monooxygenasePRO_0000360894Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi282458.SAR0883.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6GIG7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the nitronate monooxygenase family.Curated

    Phylogenomic databases

    eggNOGiCOG2070.
    HOGENOMiHOG000123287.
    KOiK00459.
    OMAiMAWTATG.
    OrthoDBiEOG6G7R1T.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    InterProiIPR004136. 2Npropane_dOase.
    IPR013785. Aldolase_TIM.
    [Graphical view]
    PfamiPF03060. NMO. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6GIG7-1 [UniParc]FASTAAdd to Basket

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    MWNKNRLTQM LSIEYPIIQA GMAGSTTPKL VASVSNSGGL GTIGAGYFNT    50
    QQLEDEIDYV RQLTSNSFGV NVFVPSQQSY TSSQIENMNA WLKPYRRALH 100
    LEEPVVKITE EQQFKCHIDT IIKKQVPVCC FTFGIPNESI IKRLKEANIK 150
    LIGTATSVDE AIANEKAGMD AIVAQGSEAG GHRGSFLKPK NQLPMVGTIS 200
    LVPQIVDVVS IPVIAAGGIM DGRGVLASIV LGAEGVQMGT AFLTSQDSNA 250
    SELLRDAIIN SKETDTVVTK AFSGKLARGI NNRFIEEMSQ YEGDIPDYPI 300
    QNELTSSIRK AAANIGDKEL THMWSGQSPR LATTHPANTI MSNIINQINQ 350
    IMQYK 355
    Length:355
    Mass (Da):38,621
    Last modified:July 19, 2004 - v1
    Checksum:i6FA4F34F5A7C61AD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX571856 Genomic DNA. Translation: CAG39889.1.
    RefSeqiYP_040305.1. NC_002952.2.

    Genome annotation databases

    EnsemblBacteriaiCAG39889; CAG39889; SAR0883.
    GeneIDi2861690.
    KEGGisar:SAR0883.
    PATRICi19545299. VBIStaAur71814_0882.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX571856 Genomic DNA. Translation: CAG39889.1 .
    RefSeqi YP_040305.1. NC_002952.2.

    3D structure databases

    ProteinModelPortali Q6GIG7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 282458.SAR0883.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAG39889 ; CAG39889 ; SAR0883 .
    GeneIDi 2861690.
    KEGGi sar:SAR0883.
    PATRICi 19545299. VBIStaAur71814_0882.

    Phylogenomic databases

    eggNOGi COG2070.
    HOGENOMi HOG000123287.
    KOi K00459.
    OMAi MAWTATG.
    OrthoDBi EOG6G7R1T.

    Enzyme and pathway databases

    BioCyci SAUR282458:GJA5-884-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    InterProi IPR004136. 2Npropane_dOase.
    IPR013785. Aldolase_TIM.
    [Graphical view ]
    Pfami PF03060. NMO. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MRSA252.

    Entry informationi

    Entry namei2NPD_STAAR
    AccessioniPrimary (citable) accession number: Q6GIG7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 20, 2009
    Last sequence update: July 19, 2004
    Last modified: October 1, 2014
    This is version 69 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3