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Protein

Serine protease HtrA-like

Gene

SAR0992

Organism
Staphylococcus aureus (strain MRSA252)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei504Charge relay systemSequence analysis1
Active sitei534Charge relay systemSequence analysis1
Active sitei619Charge relay systemSequence analysis1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Serine protease

Names & Taxonomyi

Protein namesi
Recommended name:
Serine protease HtrA-like (EC:3.4.21.-)
Gene namesi
Ordered Locus Names:SAR0992
OrganismiStaphylococcus aureus (strain MRSA252)
Taxonomic identifieri282458 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei410 – 430HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002524681 – 769Serine protease HtrA-likeAdd BLAST769

Proteomic databases

PRIDEiQ6GI62

Structurei

3D structure databases

ProteinModelPortaliQ6GI62
SMRiQ6GI62
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini680 – 733PDZAdd BLAST54

Sequence similaritiesi

Belongs to the peptidase S1C family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000279952
OMAiRNMAIND

Family and domain databases

InterProiView protein in InterPro
IPR001478 PDZ
IPR036034 PDZ_sf
IPR009003 Peptidase_S1_PA
IPR001940 Peptidase_S1C
PfamiView protein in Pfam
PF13180 PDZ_2, 1 hit
PRINTSiPR00834 PROTEASES2C
SMARTiView protein in SMART
SM00228 PDZ, 1 hit
SUPFAMiSSF50156 SSF50156, 1 hit
SSF50494 SSF50494, 1 hit

Sequencei

Sequence statusi: Complete.

Q6GI62-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDIGKKHVIP KSQYRRKRRE FFHNEDREEN LNQHQDKQNI DNTTSKKADK
60 70 80 90 100
QIHKDSIDKH ERFKNSLSSH LEQRNRDVNE NKAEESKSNQ GSKSAYNKDH
110 120 130 140 150
YLTDDVSKKQ NSLDSVDQDT EKSKYYEQNT EATLSTNSTD KVESTDMRKL
160 170 180 190 200
SSDKNKVGHE EQHVLSKPSE HDKETRIDFE SSRTDSDSSM QTEKIKKDSS
210 220 230 240 250
DGNKSSNLKS EVISDKSNSV PILSESDDEV NNQKPLTLPE EQKLKRQQSQ
260 270 280 290 300
NEQTKTYTYG DSEQNDKSNH ENDLSHHTPS ISDDKDYVMR EDHIVDDNPD
310 320 330 340 350
NDINTPSLSK IDDDRKLDEK IHVEDKHKQN ADSSETVGYQ SQSSASHRST
360 370 380 390 400
EKRNMAINDH DKLNGQKPNT KTSANNNQKK ATSKLNKGRA TNNNYSAILK
410 420 430 440 450
KFWMMYWPKL VILMGIIILI VILNAIFNNV NKNDRMNDNN DADAQKYTTT
460 470 480 490 500
MKNANNAVKS VVTVENETSK DSSLPKDKAS QDEVGSGVVY KKSGDTLYIV
510 520 530 540 550
TNAHVVGDKE NQKITFSNNK SVVGKVLGKD KWSDLAVVKA TSSDSSVKEI
560 570 580 590 600
AIGDSNNLVL GEPILVVGNP LGVDFKGTVT EGIISGLNRN VPIDFDKDNK
610 620 630 640 650
YDMLMKAFQI DASVNPGNSG GAVVNREGKL IGVVAAKISM PNVENMSFAI
660 670 680 690 700
PVNEVQKIVK ELETKGKIDY PDVGVKMKNI ASLNSFERQA VKLLGKVKNG
710 720 730 740 750
VVVDQVDNNG LADQSGLKKG DVITELDGKL LEDDLRFRQI IFSHKDDLKS
760
ITAKIYRDGK EKEINIKLK
Length:769
Mass (Da):86,353
Last modified:July 19, 2004 - v1
Checksum:iE7E17A560179FA71
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571856 Genomic DNA Translation: CAG39997.1

Genome annotation databases

EnsemblBacteriaiCAG39997; CAG39997; SAR0992
KEGGisar:SAR0992

Similar proteinsi

Entry informationi

Entry nameiHTRAL_STAAR
AccessioniPrimary (citable) accession number: Q6GI62
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: July 19, 2004
Last modified: May 23, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health