Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative aldehyde dehydrogenase SAR2210

Gene

SAR2210

Organism
Staphylococcus aureus (strain MRSA252)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei245 – 2451By similarity
Active sitei279 – 2791By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi201 – 2077NADBy similarity

GO - Molecular functioni

  1. aldehyde dehydrogenase (NAD) activity Source: UniProtKB-EC
  2. aldehyde dehydrogenase [NAD(P)+] activity Source: InterPro

GO - Biological processi

  1. cellular aldehyde metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciSAUR282458:GJA5-2244-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative aldehyde dehydrogenase SAR2210 (EC:1.2.1.3)
Gene namesi
Ordered Locus Names:SAR2210
OrganismiStaphylococcus aureus (strain MRSA252)
Taxonomic identifieri282458 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000000596: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 475475Putative aldehyde dehydrogenase SAR2210PRO_0000293554Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi282458.SAR2210.

Structurei

3D structure databases

ProteinModelPortaliQ6GEV3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Phylogenomic databases

eggNOGiCOG1012.
HOGENOMiHOG000271505.
KOiK00128.
OMAiNINTAMK.
OrthoDBiEOG6BS8QW.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6GEV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRDYTKQYIN GEWVESNSNE TIEVINPATE EVIGKVAKGN KADVDKAVEA
60 70 80 90 100
ADNVYLEFRH TSVKERQALL DKIVKEYENR KDDIVQAITD ELGAPLSLSE
110 120 130 140 150
RVHYQMGLNH FVAARDALDN YEFEERRGDD LVVKEAIGVS GLITPWNFPT
160 170 180 190 200
NQTSLKLAAA FAAGSPVVLK PSEETPFAAV ILAEIFDKVG VPKGVFNLVN
210 220 230 240 250
GDGAGVGNPL SEHPKVRMMS FTGSGPTGSK IMEKAAKDFK KVSLELGGKS
260 270 280 290 300
PYIVLDDVDI KEAAKATTGK VVNNTGQVCT AGTRVLVPNK IKDAFLAELK
310 320 330 340 350
EQFSQVRVGN PREDGTQVGP IISKKQFDQV QNYINKGIEE GAELFYGGPG
360 370 380 390 400
KPEGLEKGYF ARPTIFINVD NQMTIAQEEI FGPVMSVITY NDLDEAIQIA
410 420 430 440 450
NDTKYGLAGY VIGKDKETLH KVARSIEAGT VEINEAGRKP DLPFGGYKQS
460 470
GLGREWGDYG IEEFLEVKSI AGYFK
Length:475
Mass (Da):51,968
Last modified:July 19, 2004 - v1
Checksum:i6D88272B7D42A6BC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571856 Genomic DNA. Translation: CAG41191.1.
RefSeqiYP_041570.1. NC_002952.2.

Genome annotation databases

EnsemblBacteriaiCAG41191; CAG41191; SAR2210.
GeneIDi2861006.
KEGGisar:SAR2210.
PATRICi19548069. VBIStaAur71814_2220.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571856 Genomic DNA. Translation: CAG41191.1.
RefSeqiYP_041570.1. NC_002952.2.

3D structure databases

ProteinModelPortaliQ6GEV3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi282458.SAR2210.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAG41191; CAG41191; SAR2210.
GeneIDi2861006.
KEGGisar:SAR2210.
PATRICi19548069. VBIStaAur71814_2220.

Phylogenomic databases

eggNOGiCOG1012.
HOGENOMiHOG000271505.
KOiK00128.
OMAiNINTAMK.
OrthoDBiEOG6BS8QW.

Enzyme and pathway databases

BioCyciSAUR282458:GJA5-2244-MONOMER.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MRSA252.

Entry informationi

Entry nameiALD1_STAAR
AccessioniPrimary (citable) accession number: Q6GEV3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: July 19, 2004
Last modified: March 4, 2015
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.