Q6GEM7 (Q6GEM7_STAAR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hyaluronate lyase 2 EMBL CAG41271.1
EC=4.2.2.1 EMBL CAG41271.1

Gene names

Name:	hysA2 EMBL CAG41271.1
Ordered Locus Names:	SAR2292

Organism

Staphylococcus aureus (strain MRSA252) [Complete proteome] [HAMAP]

Taxonomic identifier

282458 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	808 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Lyase EMBL CAG41271.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro
Molecular function	carbohydrate binding Inferred from electronic annotation. Source: InterPro hyaluronate lyase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6GEM7 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: 29E5A8FB0021C0B7	FASTA	808	92,131
	10 20 30 40 50 60 MTYRMKKWQK LSTITLLMAG VITLNGGEFR SIDKHQIAVA DTNVQTTDYE KLRNIWLDVN 70 80 90 100 110 120 YGYDKYDENN PDMKKKFEAT ENEAEKLLKE MKTESDRKYL WESSKDLDTK SADMTRTYRN 130 140 150 160 170 180 IEKISEAMKH KNTKLKTDEN KTKVKDALEW LHKNAYGKEP DKKVADLTSN FKNKTSRNTN 190 200 210 220 230 240 LNWWDYEIGT PRALTNTLIL LQEDFTDEEK KKYTAPIKTF APDSDKILSS VGKSEPAKGG 250 260 270 280 290 300 NLVDISKVKL LESIIEEDKD MMKKSIDSFN TVFTYAQNSA TGKERNGFYK DGSYIDHQDV 310 320 330 340 350 360 PYTGAYGVVL LEGISQMMPM IKETPFNDSN QNDTTLKSWI DDGFMPLIYK GEMMDLSRGR 370 380 390 400 410 420 AISRENETSH SASATVMKSL LRLSDTMDKS TKAKYKKIVK TSVESDSSYK QTDYLSSYSD 430 440 450 460 470 480 ISKMKSLMED STISTNGLTQ QLKIYNDMDR VTYHNKGLDF AFGLSMTSKN VARYESINGE 490 500 510 520 530 540 NLKGWHTGAG MSYLYNSDVK HYRDNFWATA DMKRLAGTTT LDNEEPKSTD VKKSSKTFVG 550 560 570 580 590 600 GTKFDDQHAS IGMDFENQDK TLTAKKSYFI LNDKIVFLGT GIKSTDSSKN PVTTIENRKA 610 620 630 640 650 660 NDYKLYKDDT QTTNSDNQET NSLFLESTNS TQNNIGYHFL NESKITVKKE SHTGKWSDIN 670 680 690 700 710 720 KSQKDIQKTD EYYEVTQKHS NTDSKYAYVL YPGLSKDVFK SKASKVTVVK QEDDFHVVKD 730 740 750 760 770 780 NESVWAGINY SDSAKTFEIN NTKVEVKAKG MFILTKKDDN TYECSFYNPE STNSVSDIES 790 800 KISMTGYSII NKNTSTSNES GVRFELTK

References

[1]

"Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance." Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J., Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A., Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C., Clark L., Corton C. , Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z., Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N., Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M., Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J. Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004) [PubMed: 15213324] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX571856 Genomic DNA. Translation: CAG41271.1.
RefSeq	YP_041646.1. NC_002952.2.
3D structure databases
ProteinModelPortal	Q6GEM7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6GEM7.
Protein family/group databases
CAZy	PL8. Polysaccharide Lyase Family 8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000020549; EBSTAP00000019885; EBSTAG00000020548.
GeneID	2859654.
GenomeReviews	Gene locus SAR2292 in contig BX571856_GR.
KEGG	sar:SAR2292.
PATRIC	19548253. VBIStaAur71814_2303.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	NOG04835.
GeneTree	EBGT00050000023753.
HOGENOM	HBG693731.
OMA	GSYIDHT.
ProtClustDB	CLSK885824.
Enzyme and pathway databases
BioCyc	SAUR282458:SAR2292-MONOMER.
Family and domain databases
InterPro	IPR008929. Chondroitin_lyas. IPR011013. Glyco_hydro-type_carb-bd. IPR014718. Glyco_hydro-type_carb-bd_sub. IPR011071. Lyase_8-like_C. IPR012970. Lyase_8_alpha_N. IPR004103. Lyase_8_C. IPR003159. Lyase_8_central_dom. IPR012329. Lyase_8_N. [Graphical view]
Gene3D	G3DSA:2.70.98.10. Glyco_hydro_42_D5. 1 hit. G3DSA:2.60.220.10. Lyase_8_C. 1 hit. G3DSA:1.50.10.100. Lyase_8_N. 1 hit.
KO	K01727.
Pfam	PF02278. Lyase_8. 1 hit. PF02884. Lyase_8_C. 1 hit. PF08124. Lyase_8_N. 1 hit. [Graphical view]
SUPFAM	SSF48230. Chondroitin_lyas. 1 hit. SSF74650. Gal_mut_like. 1 hit. SSF49863. Lyase_like_C. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q6GEM7_STAAR

Accession

Primary (citable) accession number: Q6GEM7

Entry history

Integrated into UniProtKB/TrEMBL:	July 19, 2004
Last sequence update:	July 19, 2004
Last modified:	December 14, 2011
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)