Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6GDU6

- GTAB_STAAR

UniProt

Q6GDU6 - GTAB_STAAR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

UTP--glucose-1-phosphate uridylyltransferase

Gene

gtaB

Organism
Staphylococcus aureus (strain MRSA252)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the formation of UDP-glucose from glucose-1-phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in the S.aureus membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA) By similarity.By similarity

Catalytic activityi

UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.

Pathwayi

GO - Molecular functioni

  1. UTP:glucose-1-phosphate uridylyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. enterobacterial common antigen biosynthetic process Source: UniProtKB-UniPathway
  2. UDP-glucose metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Carbohydrate metabolism

Enzyme and pathway databases

BioCyciSAUR282458:GJA5-2622-MONOMER.
UniPathwayiUPA00894.

Names & Taxonomyi

Protein namesi
Recommended name:
UTP--glucose-1-phosphate uridylyltransferase (EC:2.7.7.9)
Alternative name(s):
Alpha-D-glucosyl-1-phosphate uridylyltransferase
UDP-glucose pyrophosphorylase
Short name:
UDPGP
Uridine diphosphoglucose pyrophosphorylase
Gene namesi
Name:gtaB
Ordered Locus Names:SAR2579
OrganismiStaphylococcus aureus (strain MRSA252)
Taxonomic identifieri282458 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000000596: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 288288UTP--glucose-1-phosphate uridylyltransferasePRO_0000308307Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi282458.SAR2579.

Structurei

3D structure databases

ProteinModelPortaliQ6GDU6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UDPGP type 2 family.Curated

Phylogenomic databases

eggNOGiCOG1210.
HOGENOMiHOG000283477.
KOiK00963.
OMAiEDYFDTQ.
OrthoDBiEOG6Z9B3V.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR005771. GalU_uridylyltTrfase_bac/arc.
IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.
TIGRFAMsiTIGR01099. galU. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6GDU6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKKIKKAIIP AAGLGTRFLP ATKAMPKEML PILDKPTIQY IIEEAARAGI
60 70 80 90 100
EDIIIVTGRH KRAIEDHFDS QKELEMVLKE KGKSELLEKV QYSTELANIF
110 120 130 140 150
YVRQKEQKGL GHAISSARQF IGNEPFAVLL GDDIVESEVP AVKQLIDVYE
160 170 180 190 200
ETGHSVIGVQ EVPEADTHRY GIIDPLTKNG RQYEVKKFVE KPAQGTAPSN
210 220 230 240 250
LAIMGRYVLT PEIFDYLKTQ KEGAGNEIQL TDAIERMNND NQVYAYDFEG
260 270 280
ERYDVGEKLG FVKTTIEYAL KDDSMREELT RFIKELGL
Length:288
Mass (Da):32,523
Last modified:July 19, 2004 - v1
Checksum:i526BFD93999D4194
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571856 Genomic DNA. Translation: CAG41559.1.
RefSeqiYP_041927.1. NC_002952.2.

Genome annotation databases

EnsemblBacteriaiCAG41559; CAG41559; SAR2579.
GeneIDi2859946.
KEGGisar:SAR2579.
PATRICi19548854. VBIStaAur71814_2605.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571856 Genomic DNA. Translation: CAG41559.1 .
RefSeqi YP_041927.1. NC_002952.2.

3D structure databases

ProteinModelPortali Q6GDU6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 282458.SAR2579.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAG41559 ; CAG41559 ; SAR2579 .
GeneIDi 2859946.
KEGGi sar:SAR2579.
PATRICi 19548854. VBIStaAur71814_2605.

Phylogenomic databases

eggNOGi COG1210.
HOGENOMi HOG000283477.
KOi K00963.
OMAi EDYFDTQ.
OrthoDBi EOG6Z9B3V.

Enzyme and pathway databases

UniPathwayi UPA00894 .
BioCyci SAUR282458:GJA5-2622-MONOMER.

Family and domain databases

Gene3Di 3.90.550.10. 1 hit.
InterProi IPR005771. GalU_uridylyltTrfase_bac/arc.
IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view ]
Pfami PF00483. NTP_transferase. 1 hit.
[Graphical view ]
SUPFAMi SSF53448. SSF53448. 1 hit.
TIGRFAMsi TIGR01099. galU. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MRSA252.

Entry informationi

Entry nameiGTAB_STAAR
AccessioniPrimary (citable) accession number: Q6GDU6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: July 19, 2004
Last modified: October 1, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3