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Q6GDJ7

- ALF1_STAAR

UniProt

Q6GDJ7 - ALF1_STAAR

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Protein

Fructose-bisphosphate aldolase class 1

Gene

fda

Organism
Staphylococcus aureus (strain MRSA252)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei175 – 1751Proton acceptorUniRule annotation
Active sitei212 – 2121Schiff-base intermediate with dihydroxyacetone-PUniRule annotation

GO - Molecular functioni

  1. fructose-bisphosphate aldolase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

Schiff base

Enzyme and pathway databases

BioCyciSAUR282458:GJA5-2724-MONOMER.
UniPathwayiUPA00109; UER00183.

Names & Taxonomyi

Protein namesi
Recommended name:
Fructose-bisphosphate aldolase class 1UniRule annotation (EC:4.1.2.13UniRule annotation)
Alternative name(s):
Fructose-bisphosphate aldolase class I
Short name:
FBP aldolaseUniRule annotation
Gene namesi
Name:fdaUniRule annotation
Ordered Locus Names:SAR2684
OrganismiStaphylococcus aureus (strain MRSA252)
Taxonomic identifieri282458 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000000596: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 296295Fructose-bisphosphate aldolase class 1PRO_0000216906Add
BLAST

Proteomic databases

PRIDEiQ6GDJ7.

Interactioni

Protein-protein interaction databases

STRINGi282458.SAR2684.

Structurei

3D structure databases

ProteinModelPortaliQ6GDJ7.
SMRiQ6GDJ7. Positions 1-294.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class I fructose-bisphosphate aldolase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG3588.
HOGENOMiHOG000073502.
KOiK01623.
OMAiYTGDYLA.
OrthoDBiEOG6M6JJT.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00729. FBP_aldolase_1.
InterProiIPR013785. Aldolase_TIM.
IPR000741. FBA_I.
IPR023014. FBA_I_Gram+-type.
[Graphical view]
PfamiPF00274. Glycolytic. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q6GDJ7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNKEQLEKMK NGKGFIAALD QSGGSTPKAL KEYGVNEDQY SNEDEMFQLV
60 70 80 90 100
HDMRTRVVTS PSFSPDKILG AILFEQTMDR EVEGKYTADY LADKGVVPFL
110 120 130 140 150
KVDKGLAEEQ NGVQLMKPID NLDSLLDRAN ERHIFGTKMR SNILELNEQG
160 170 180 190 200
IKDVVEQQFE VAKQIIAKGL VPIIEPEVNI NAKDKAEIEK VLKAELKKGL
210 220 230 240 250
DSLNADQLVM LKLTIPTEAN LYKDLAEHPN VVRIVVLSGG YSREKANELL
260 270 280 290
KDNAELIASF SRALASDLRA GQSKEEFDKA LGDAVESIYD ASVNKN
Length:296
Mass (Da):32,913
Last modified:January 23, 2007 - v3
Checksum:iCB1EF5FA63576D51
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571856 Genomic DNA. Translation: CAG41661.1.
RefSeqiYP_042026.1. NC_002952.2.

Genome annotation databases

EnsemblBacteriaiCAG41661; CAG41661; SAR2684.
GeneIDi2860659.
KEGGisar:SAR2684.
PATRICi19549076. VBIStaAur71814_2716.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571856 Genomic DNA. Translation: CAG41661.1 .
RefSeqi YP_042026.1. NC_002952.2.

3D structure databases

ProteinModelPortali Q6GDJ7.
SMRi Q6GDJ7. Positions 1-294.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 282458.SAR2684.

Proteomic databases

PRIDEi Q6GDJ7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAG41661 ; CAG41661 ; SAR2684 .
GeneIDi 2860659.
KEGGi sar:SAR2684.
PATRICi 19549076. VBIStaAur71814_2716.

Phylogenomic databases

eggNOGi COG3588.
HOGENOMi HOG000073502.
KOi K01623.
OMAi YTGDYLA.
OrthoDBi EOG6M6JJT.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00183 .
BioCyci SAUR282458:GJA5-2724-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00729. FBP_aldolase_1.
InterProi IPR013785. Aldolase_TIM.
IPR000741. FBA_I.
IPR023014. FBA_I_Gram+-type.
[Graphical view ]
Pfami PF00274. Glycolytic. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MRSA252.

Entry informationi

Entry nameiALF1_STAAR
AccessioniPrimary (citable) accession number: Q6GDJ7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: January 23, 2007
Last modified: October 1, 2014
This is version 65 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3