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Q6GCV9

- ALDA_STAAS

UniProt

Q6GCV9 - ALDA_STAAS

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Protein

Putative aldehyde dehydrogenase AldA

Gene
aldA, SAS0142
Organism
Staphylococcus aureus (strain MSSA476)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei256 – 2561 By similarity
Active sitei290 – 2901 By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi212 – 2187NAD By similarity

GO - Molecular functioni

  1. aldehyde dehydrogenase (NAD) activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Names & Taxonomyi

Protein namesi
Recommended name:
Putative aldehyde dehydrogenase AldA (EC:1.2.1.3)
Gene namesi
Name:aldA
Ordered Locus Names:SAS0142
OrganismiStaphylococcus aureus (strain MSSA476)
Taxonomic identifieri282459 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000002201: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 495495Putative aldehyde dehydrogenase AldAPRO_0000056459Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi282459.SAS0142.

Structurei

3D structure databases

ProteinModelPortaliQ6GCV9.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1012.
HOGENOMiHOG000271505.
KOiK00128.
OMAiMACWKMA.
OrthoDBiEOG6BS8QW.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6GCV9-1 [UniParc]FASTAAdd to Basket

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MAVNVRDYIA ENYGLFINGE FVKGSSDETI EVTNPATGET LSHITRAKDK    50
DVDHAVKVAQ DAFESWSLTS KSERAQMLRD IGDKLMAQKD KIAMIETLNN 100
GKPIRETTAI DIPFAARHFH YFASVIETEE GTVNDIDKDT MSIVRHEPIG 150
VVGAVVAWNF PMLLAAWKIA PAIAAGNTIV IQPSSSTPLS LLEVAKIFQE 200
VLPKGVVNIL TGKGSESGNA IFNHDGVDKL SFTGSTDVGY QVAEAAAKHL 250
VPATLELGGK SANIILDDAN LDLAVEGIQL GILFNQGEVC SAGSRLLVHE 300
KIYDQLVPRL QEAFSNIKVG DPQDEATQMG SQTGKDQLDK IQSYIDAAKE 350
SDAQILAGGH RLTENGLDKG FFFEPTLIAV PDNHHKLAQE EIFGPVLTVI 400
KVKDDQEAID IANDSEYGLA GGVFSQNITR ALNIAKAVRT GRIWINTYNQ 450
VPEGAPFGGY KKSGIGRETY KGALSNYQQV KNIYIDTSNA LKGLY 495
Length:495
Mass (Da):53,646
Last modified:July 19, 2004 - v1
Checksum:i23F1F88F80A192ED
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571857 Genomic DNA. Translation: CAG41910.1.
RefSeqiYP_042264.1. NC_002953.3.

Genome annotation databases

GeneIDi2862480.
KEGGisas:SAS0142.
PATRICi19549628. VBIStaAur96780_0152.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571857 Genomic DNA. Translation: CAG41910.1 .
RefSeqi YP_042264.1. NC_002953.3.

3D structure databases

ProteinModelPortali Q6GCV9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 282459.SAS0142.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 2862480.
KEGGi sas:SAS0142.
PATRICi 19549628. VBIStaAur96780_0152.

Phylogenomic databases

eggNOGi COG1012.
HOGENOMi HOG000271505.
KOi K00128.
OMAi MACWKMA.
OrthoDBi EOG6BS8QW.

Family and domain databases

Gene3Di 3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProi IPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view ]
Pfami PF00171. Aldedh. 1 hit.
[Graphical view ]
SUPFAMi SSF53720. SSF53720. 1 hit.
PROSITEi PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MSSA476.

Entry informationi

Entry nameiALDA_STAAS
AccessioniPrimary (citable) accession number: Q6GCV9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: July 19, 2004
Last modified: June 11, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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