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Q6GCV9

- ALDA_STAAS

UniProt

Q6GCV9 - ALDA_STAAS

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Protein
Putative aldehyde dehydrogenase AldA
Gene
aldA, SAS0142
Organism
Staphylococcus aureus (strain MSSA476)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei256 – 2561 By similarity
Active sitei290 – 2901 By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi212 – 2187NAD By similarity

GO - Molecular functioni

  1. aldehyde dehydrogenase (NAD) activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative aldehyde dehydrogenase AldA (EC:1.2.1.3)
    Gene namesi
    Name:aldA
    Ordered Locus Names:SAS0142
    OrganismiStaphylococcus aureus (strain MSSA476)
    Taxonomic identifieri282459 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000002201: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 495495Putative aldehyde dehydrogenase AldA
    PRO_0000056459Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi282459.SAS0142.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6GCV9.

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1012.
    HOGENOMiHOG000271505.
    KOiK00128.
    OMAiMACWKMA.
    OrthoDBiEOG6BS8QW.

    Family and domain databases

    Gene3Di3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProiIPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view]
    PfamiPF00171. Aldedh. 1 hit.
    [Graphical view]
    SUPFAMiSSF53720. SSF53720. 1 hit.
    PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6GCV9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAVNVRDYIA ENYGLFINGE FVKGSSDETI EVTNPATGET LSHITRAKDK    50
    DVDHAVKVAQ DAFESWSLTS KSERAQMLRD IGDKLMAQKD KIAMIETLNN 100
    GKPIRETTAI DIPFAARHFH YFASVIETEE GTVNDIDKDT MSIVRHEPIG 150
    VVGAVVAWNF PMLLAAWKIA PAIAAGNTIV IQPSSSTPLS LLEVAKIFQE 200
    VLPKGVVNIL TGKGSESGNA IFNHDGVDKL SFTGSTDVGY QVAEAAAKHL 250
    VPATLELGGK SANIILDDAN LDLAVEGIQL GILFNQGEVC SAGSRLLVHE 300
    KIYDQLVPRL QEAFSNIKVG DPQDEATQMG SQTGKDQLDK IQSYIDAAKE 350
    SDAQILAGGH RLTENGLDKG FFFEPTLIAV PDNHHKLAQE EIFGPVLTVI 400
    KVKDDQEAID IANDSEYGLA GGVFSQNITR ALNIAKAVRT GRIWINTYNQ 450
    VPEGAPFGGY KKSGIGRETY KGALSNYQQV KNIYIDTSNA LKGLY 495
    Length:495
    Mass (Da):53,646
    Last modified:July 19, 2004 - v1
    Checksum:i23F1F88F80A192ED
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX571857 Genomic DNA. Translation: CAG41910.1.
    RefSeqiYP_042264.1. NC_002953.3.

    Genome annotation databases

    GeneIDi2862480.
    KEGGisas:SAS0142.
    PATRICi19549628. VBIStaAur96780_0152.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX571857 Genomic DNA. Translation: CAG41910.1 .
    RefSeqi YP_042264.1. NC_002953.3.

    3D structure databases

    ProteinModelPortali Q6GCV9.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 282459.SAS0142.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 2862480.
    KEGGi sas:SAS0142.
    PATRICi 19549628. VBIStaAur96780_0152.

    Phylogenomic databases

    eggNOGi COG1012.
    HOGENOMi HOG000271505.
    KOi K00128.
    OMAi MACWKMA.
    OrthoDBi EOG6BS8QW.

    Family and domain databases

    Gene3Di 3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProi IPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view ]
    Pfami PF00171. Aldedh. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53720. SSF53720. 1 hit.
    PROSITEi PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MSSA476.

    Entry informationi

    Entry nameiALDA_STAAS
    AccessioniPrimary (citable) accession number: Q6GCV9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 22, 2005
    Last sequence update: July 19, 2004
    Last modified: June 11, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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