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Q6GCV9 (ALDA_STAAS) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative aldehyde dehydrogenase AldA

EC=1.2.1.3
Gene names
Name:aldA
Ordered Locus Names:SAS0142
OrganismStaphylococcus aureus (strain MSSA476) [Complete proteome] [HAMAP]
Taxonomic identifier282459 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length495 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functionaldehyde dehydrogenase (NAD) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 495495Putative aldehyde dehydrogenase AldA
PRO_0000056459

Regions

Nucleotide binding212 – 2187NAD By similarity

Sites

Active site2561 By similarity
Active site2901 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6GCV9 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 23F1F88F80A192ED

FASTA49553,646
        10         20         30         40         50         60 
MAVNVRDYIA ENYGLFINGE FVKGSSDETI EVTNPATGET LSHITRAKDK DVDHAVKVAQ 

        70         80         90        100        110        120 
DAFESWSLTS KSERAQMLRD IGDKLMAQKD KIAMIETLNN GKPIRETTAI DIPFAARHFH 

       130        140        150        160        170        180 
YFASVIETEE GTVNDIDKDT MSIVRHEPIG VVGAVVAWNF PMLLAAWKIA PAIAAGNTIV 

       190        200        210        220        230        240 
IQPSSSTPLS LLEVAKIFQE VLPKGVVNIL TGKGSESGNA IFNHDGVDKL SFTGSTDVGY 

       250        260        270        280        290        300 
QVAEAAAKHL VPATLELGGK SANIILDDAN LDLAVEGIQL GILFNQGEVC SAGSRLLVHE 

       310        320        330        340        350        360 
KIYDQLVPRL QEAFSNIKVG DPQDEATQMG SQTGKDQLDK IQSYIDAAKE SDAQILAGGH 

       370        380        390        400        410        420 
RLTENGLDKG FFFEPTLIAV PDNHHKLAQE EIFGPVLTVI KVKDDQEAID IANDSEYGLA 

       430        440        450        460        470        480 
GGVFSQNITR ALNIAKAVRT GRIWINTYNQ VPEGAPFGGY KKSGIGRETY KGALSNYQQV 

       490 
KNIYIDTSNA LKGLY 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX571857 Genomic DNA. Translation: CAG41910.1.
RefSeqYP_042264.1. NC_002953.3.

3D structure databases

ProteinModelPortalQ6GCV9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING282459.SAS0142.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2862480.
KEGGsas:SAS0142.
PATRIC19549628. VBIStaAur96780_0152.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1012.
HOGENOMHOG000271505.
KOK00128.
OMAVAYHIYE.
OrthoDBEOG6BS8QW.
ProtClustDBCLSK884447.

Family and domain databases

Gene3D3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. SSF53720. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALDA_STAAS
AccessionPrimary (citable) accession number: Q6GCV9
Entry history
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: July 19, 2004
Last modified: November 13, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families