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Protein

ESAT-6 secretion machinery protein EssB

Gene

essB

Organism
Staphylococcus aureus (strain MSSA476)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Component of the ESAT-6 secretion system (Ess). Required for the secretion of EsxA and EsxB.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Virulence

Names & Taxonomyi

Protein namesi
Recommended name:
ESAT-6 secretion machinery protein EssBBy similarity
Gene namesi
Name:essBBy similarity
Ordered Locus Names:SAS0262
OrganismiStaphylococcus aureus (strain MSSA476)
Taxonomic identifieri282459 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 229CytoplasmicBy similarityAdd BLAST229
Transmembranei230 – 250HelicalSequence analysisAdd BLAST21
Topological domaini251 – 444ExtracellularBy similarityAdd BLAST194

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000870661 – 444ESAT-6 secretion machinery protein EssBAdd BLAST444

Structurei

3D structure databases

ProteinModelPortaliQ6GCI6.
SMRiQ6GCI6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili387 – 443Sequence analysisAdd BLAST57

Sequence similaritiesi

Belongs to the EssB family.Curated

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000279762.
OMAiFLHYGVK.

Family and domain databases

InterProiIPR018778. T7SS_EssB.
[Graphical view]
PfamiPF10140. YukC. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03926. T7_EssB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6GCI6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKNHNPKNE MQDMLTPLDA EEAAKTKLRL DMREIPKSSI KPEHFHLMYL
60 70 80 90 100
LEQHSPYFID AELTELRDSF QIHYDINDNH TPFDNIKSFT KNEKLRYLLN
110 120 130 140 150
IKNLEEVNRT RYTFVLAPDE LFFTRDGLPI AKTRGLQNVV DPLPVSEAEF
160 170 180 190 200
LTRYKALVIC AFNEKQSFDA LVEGNLELHK GTPFETKVIE AATLDLLTAF
210 220 230 240 250
LDEQYQKQEQ DYSQNYAYVR KVGHTVFKWV AIGMTTLSVL LIAFLAFLYF
260 270 280 290 300
SVMKHNERIE KGYQAFVKDD YTQVLNTYDD LDGKKLDKEA LYIYAKSYIQ
310 320 330 340 350
TNKQGLEKDK KENLLNNVTP NSNKDYLLYW MELGQGHLDE AINIATYLDD
360 370 380 390 400
NDITKLALIN KLNEIKNNGD LSNDKRSEET KKYNDKLQDI LDKEKQVKDE
410 420 430 440
KAKSEEEKAK AKDEKLKQQE ENEKKQKEQA QKDKEKRQEA ERKK
Length:444
Mass (Da):52,024
Last modified:July 19, 2004 - v1
Checksum:iFACCFE3353DE1F77
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571857 Genomic DNA. Translation: CAG42033.1.
RefSeqiWP_000240338.1. NC_002953.3.

Genome annotation databases

GeneIDi28379392.
KEGGisas:SAS0262.
PATRICi19549878. VBIStaAur96780_0277.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571857 Genomic DNA. Translation: CAG42033.1.
RefSeqiWP_000240338.1. NC_002953.3.

3D structure databases

ProteinModelPortaliQ6GCI6.
SMRiQ6GCI6.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi28379392.
KEGGisas:SAS0262.
PATRICi19549878. VBIStaAur96780_0277.

Phylogenomic databases

HOGENOMiHOG000279762.
OMAiFLHYGVK.

Family and domain databases

InterProiIPR018778. T7SS_EssB.
[Graphical view]
PfamiPF10140. YukC. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03926. T7_EssB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiESSB_STAAS
AccessioniPrimary (citable) accession number: Q6GCI6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: July 19, 2004
Last modified: November 2, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.