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Protein

Methionine import ATP-binding protein MetN 1

Gene

metN1

Organism
Staphylococcus aureus (strain MSSA476)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi38 – 45ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processAmino-acid transport, Transport
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Methionine import ATP-binding protein MetN 1UniRule annotation (EC:3.6.3.-UniRule annotation)
Gene namesi
Name:metN1UniRule annotation
Ordered Locus Names:SAS0419
OrganismiStaphylococcus aureus (strain MSSA476)
Taxonomic identifieri282459 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus

Subcellular locationi

  • Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002703931 – 341Methionine import ATP-binding protein MetN 1Add BLAST341

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ).UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ6GC27.
SMRiQ6GC27.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 241ABC transporterUniRule annotationAdd BLAST240

Sequence similaritiesi

Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. [View classification]UniRule annotation

Phylogenomic databases

KOiK02071.
OMAiLIRLINC.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR026253. ABC_MetN.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR017908. ABC_transprt_methionine_MetN_C.
IPR018449. NIL_domain.
IPR027417. P-loop_NTPase.
PANTHERiPTHR43166:SF1. PTHR43166:SF1. 1 hit.
PfamiView protein in Pfam
PF00005. ABC_tran. 1 hit.
PF09383. NIL. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SM00930. NIL. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51264. METN. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6GC27-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIEFRQVSKT FNKKKQKIDA LKDVSFTVNR NDIFGVIGYS GAGKSTLVRL
60 70 80 90 100
VNHLEAASNG QVIVDGHDIT NYSDKMMRDI KKDIGMIFQH FNLLNSATVF
110 120 130 140 150
KNVAMPLILS KKSKTEIKQR VTEMLEFVGL SDKKDQFPEE LSGGQKQRVA
160 170 180 190 200
IARALVTNPK ILLCDEATSA LDPATTASIL TLLKNVNQTF GITIMMITHE
210 220 230 240 250
MRVIKDICNR VAVMEKGQVV ETGTVKEVFS HPKTTIAQNF VSTVIQTEPS
260 270 280 290 300
TSLIRRLNDE QVGDFKDYKI FVEETQVTQP IINDLIQICG REVKILFSSM
310 320 330 340
SEIQGNTVCY MWLRFNMDQQ FDDTAINQYF KEKNIQFEEV H
Length:341
Mass (Da):38,676
Last modified:July 19, 2004 - v1
Checksum:i4D3583780CDFE6C9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571857 Genomic DNA. Translation: CAG42193.1.
RefSeqiWP_000569289.1. NC_002953.3.

Genome annotation databases

KEGGisas:SAS0419.
PATRICi19550202. VBIStaAur96780_0439.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571857 Genomic DNA. Translation: CAG42193.1.
RefSeqiWP_000569289.1. NC_002953.3.

3D structure databases

ProteinModelPortaliQ6GC27.
SMRiQ6GC27.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

KEGGisas:SAS0419.
PATRICi19550202. VBIStaAur96780_0439.

Phylogenomic databases

KOiK02071.
OMAiLIRLINC.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR026253. ABC_MetN.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR017908. ABC_transprt_methionine_MetN_C.
IPR018449. NIL_domain.
IPR027417. P-loop_NTPase.
PANTHERiPTHR43166:SF1. PTHR43166:SF1. 1 hit.
PfamiView protein in Pfam
PF00005. ABC_tran. 1 hit.
PF09383. NIL. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SM00930. NIL. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51264. METN. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMETN1_STAAS
AccessioniPrimary (citable) accession number: Q6GC27
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: July 19, 2004
Last modified: April 12, 2017
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.