Q6GBP8 (PTAS_STAAS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphate acetyltransferase
EC=2.3.1.8

Alternative name(s):
Phosphotransacetylase

Gene names

Name:	pta
Ordered Locus Names:	SAS0547

Organism

Staphylococcus aureus (strain MSSA476) [Complete proteome] [HAMAP]

Taxonomic identifier

282459 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	328 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acetyl-CoA + phosphate = CoA + acetyl phosphate.
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	phosphate acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 328	328	Phosphate acetyltransferase		PRO_0000179144

Sequences

	Sequence		Length	Mass (Da)
	Q6GBP8 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: BD0C9BCCC0DCC76F	FASTA	328	34,922
	10 20 30 40 50 60 MADLLNVLKD KLSGKNVKIV LPEGEDERVL TAATQLQATD YVTPIVLGDE TKVQSLAQKL 70 80 90 100 110 120 DLDISNIELI NPATSELKAE LVQSFVERRK GKATEEQAQE LLNNVNYFGT MLVYAGKADG 130 140 150 160 170 180 LVSGAAHSTG DTVRPALQII KTKPGVSRTS GIFFMIKGDV QYIFGDCAIN PELDSQGLAE 190 200 210 220 230 240 IAVESAKSAL SFGMDPKVAM LSFSTKGSAK SDDVTKVQEA VKLAQQKAEE EKLEAIIDGE 250 260 270 280 290 300 FQFDAAIVPG VAEKKAPGAK LQGDANVFVF PSLEAGNIGY KIAQRLGGYD AVGPVLQGLN 310 320 SPVNDLSRGC SIEDVYNLSI ITAAQALQ

References

[1]

"Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance." Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J., Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A., Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C., Clark L., Corton C. , Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z., Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N., Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M., Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J. Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004) [PubMed: 15213324] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MSSA476.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX571857 Genomic DNA. Translation: CAG42322.1.
RefSeq	YP_042675.1. NC_002953.3.
3D structure databases
ProteinModelPortal	Q6GBP8.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6GBP8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000024601; EBSTAP00000023768; EBSTAG00000024600.
GeneID	2862069.
GenomeReviews	Gene locus SAS0547 in contig BX571857_GR.
KEGG	sas:SAS0547.
PATRIC	19550502. VBIStaAur96780_0569.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0280.
GeneTree	EBGT00050000025364.
HOGENOM	HBG576804.
OMA	GCSTEDV.
ProtClustDB	PRK09653.
Enzyme and pathway databases
BioCyc	SAUR282459:SAS0547-MONOMER.
Family and domain databases
InterPro	IPR012147. P_Ac_Bu_trans. IPR004614. P_AcTrfase. IPR002505. PTA_PTB. [Graphical view]
KO	K00625.
Pfam	PF01515. PTA_PTB. 1 hit. [Graphical view]
PIRSF	PIRSF000428. P_Ac_trans. 1 hit.
TIGRFAMs	TIGR00651. Pta. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PTAS_STAAS

Accession

Primary (citable) accession number: Q6GBP8

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 19, 2005
Last sequence update:	July 19, 2004
Last modified:	January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program