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Protein

Glutamate racemase

Gene

murI

Organism
Staphylococcus aureus (strain MSSA476)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Provides the (R)-glutamate required for cell wall biosynthesis.UniRule annotation

Catalytic activityi

L-glutamate = D-glutamate.UniRule annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei72Proton donor/acceptorUniRule annotation1
Active sitei184Proton donor/acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

UniPathwayiUPA00219

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate racemaseUniRule annotation (EC:5.1.1.3UniRule annotation)
Gene namesi
Name:murIUniRule annotation
Ordered Locus Names:SAS1084
OrganismiStaphylococcus aureus (strain MSSA476)
Taxonomic identifieri282459 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000955111 – 266Glutamate racemaseAdd BLAST266

Structurei

3D structure databases

ProteinModelPortaliQ6GA64
SMRiQ6GA64
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni9 – 10Substrate bindingUniRule annotation2
Regioni41 – 42Substrate bindingUniRule annotation2
Regioni73 – 74Substrate bindingUniRule annotation2
Regioni185 – 186Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the aspartate/glutamate racemases family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000262396
KOiK01776
OMAiVYGCTHY

Family and domain databases

HAMAPiMF_00258 Glu_racemase, 1 hit
InterProiView protein in InterPro
IPR015942 Asp/Glu/hydantoin_racemase
IPR001920 Asp/Glu_race
IPR018187 Asp/Glu_racemase_AS_1
IPR033134 Asp/Glu_racemase_AS_2
IPR004391 Glu_race
PANTHERiPTHR21198:SF2 PTHR21198:SF2, 1 hit
PfamiView protein in Pfam
PF01177 Asp_Glu_race, 1 hit
SUPFAMiSSF53681 SSF53681, 2 hits
TIGRFAMsiTIGR00067 glut_race, 1 hit
PROSITEiView protein in PROSITE
PS00923 ASP_GLU_RACEMASE_1, 1 hit
PS00924 ASP_GLU_RACEMASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q6GA64-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKPIGVIDS GVGGLTVAKE IMRQLPNETI YYLGDIGRCP YGPRPGEQVK
60 70 80 90 100
QYTVEIARKL MEFDIKMLVI ACNTATAVAL EYLQKTLSIP VIGVIEPGAR
110 120 130 140 150
TAIMTTRNQN VLVLGTEGTI KSEAYRTHIK RINPHVEVHG VACPGFVPLV
160 170 180 190 200
EQMRYSDPTI TSIVIHQTLK RWRNSESDTV ILGCTHYPLL YKPIYDYFGG
210 220 230 240 250
KKTVISSGLE TAREVSALLT FSNEHASYTE HPDHRFFATG DPTHITNIIK
260
EWLNLSVNVE RISVND
Length:266
Mass (Da):29,698
Last modified:July 19, 2004 - v1
Checksum:i93BC35DB4A2C7B0E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571857 Genomic DNA Translation: CAG42859.1
RefSeqiWP_001039659.1, NC_002953.3

Genome annotation databases

KEGGisas:SAS1084

Similar proteinsi

Entry informationi

Entry nameiMURI_STAAS
AccessioniPrimary (citable) accession number: Q6GA64
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 21, 2004
Last sequence update: July 19, 2004
Last modified: March 28, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health