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Q6G9Y3

- FABD_STAAS

UniProt

Q6G9Y3 - FABD_STAAS

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Protein

Malonyl CoA-acyl carrier protein transacylase

Gene
fabD, SAS1164
Organism
Staphylococcus aureus (strain MSSA476)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Malonyl-CoA + an [acyl-carrier-protein] = CoA + a malonyl-[acyl-carrier-protein].

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei89 – 891 By similarity
Active sitei199 – 1991 By similarity

GO - Molecular functioni

  1. [acyl-carrier-protein] S-malonyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. fatty acid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

UniPathwayiUPA00094.

Names & Taxonomyi

Protein namesi
Recommended name:
Malonyl CoA-acyl carrier protein transacylase (EC:2.3.1.39)
Short name:
MCT
Gene namesi
Name:fabD
Ordered Locus Names:SAS1164
OrganismiStaphylococcus aureus (strain MSSA476)
Taxonomic identifieri282459 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000002201: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 308308Malonyl CoA-acyl carrier protein transacylasePRO_0000194223Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi282459.SAS1164.

Structurei

3D structure databases

ProteinModelPortaliQ6G9Y3.

Family & Domainsi

Sequence similaritiesi

Belongs to the FabD family.

Phylogenomic databases

eggNOGiCOG0331.
HOGENOMiHOG000036504.
KOiK00645.
OMAiIWRVWQE.
OrthoDBiEOG6W19KW.

Family and domain databases

Gene3Di3.40.366.10. 2 hits.
InterProiIPR001227. Ac_transferase_dom.
IPR014043. Acyl_transferase.
IPR016035. Acyl_Trfase/lysoPLipase.
IPR024925. Malonyl_CoA-ACP_transAc.
IPR004410. Malonyl_CoA-ACP_transAc_FabD.
IPR016036. Malonyl_transacylase_ACP-bd.
[Graphical view]
PfamiPF00698. Acyl_transf_1. 1 hit.
[Graphical view]
PIRSFiPIRSF000446. Mct. 1 hit.
SUPFAMiSSF52151. SSF52151. 2 hits.
SSF55048. SSF55048. 1 hit.
TIGRFAMsiTIGR00128. fabD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6G9Y3-1 [UniParc]FASTAAdd to Basket

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MSKTAIIFPG QGAQKVGMAQ DLFNNNDQAT EILTSAAKTL DFDILETMFT    50
DEEGKLGETE NTQPALLTHS SALLAALKNL NPDFTMGHSL GEYSSLVAAD 100
VLSFEDAVKI VRKRGQLMAQ AFPTGVGSMA AVLGLDFDKV DEICKSLSSD 150
DKIIEPANIN CPGQIVVSGH KALIDELVEK GKSLGAKRVM PLAVSGPFHS 200
SLMKVIEEDF SSYINQFEWR DAKFPVVQNV NAQGETDNEV IKSNMVKQLY 250
SPVQFINSTE WLIDQGVDHF IEIGPGKVLS GLIKKINRDV KLTSIQTLED 300
VKGWNEND 308
Length:308
Mass (Da):33,635
Last modified:July 19, 2004 - v1
Checksum:iF3FEBADB200803B4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571857 Genomic DNA. Translation: CAG42941.1.
RefSeqiWP_000047344.1. NC_002953.3.
YP_043290.1. NC_002953.3.

Genome annotation databases

GeneIDi2863668.
KEGGisas:SAS1164.
PATRICi19551785. VBIStaAur96780_1210.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571857 Genomic DNA. Translation: CAG42941.1 .
RefSeqi WP_000047344.1. NC_002953.3.
YP_043290.1. NC_002953.3.

3D structure databases

ProteinModelPortali Q6G9Y3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 282459.SAS1164.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 2863668.
KEGGi sas:SAS1164.
PATRICi 19551785. VBIStaAur96780_1210.

Phylogenomic databases

eggNOGi COG0331.
HOGENOMi HOG000036504.
KOi K00645.
OMAi IWRVWQE.
OrthoDBi EOG6W19KW.

Enzyme and pathway databases

UniPathwayi UPA00094 .

Family and domain databases

Gene3Di 3.40.366.10. 2 hits.
InterProi IPR001227. Ac_transferase_dom.
IPR014043. Acyl_transferase.
IPR016035. Acyl_Trfase/lysoPLipase.
IPR024925. Malonyl_CoA-ACP_transAc.
IPR004410. Malonyl_CoA-ACP_transAc_FabD.
IPR016036. Malonyl_transacylase_ACP-bd.
[Graphical view ]
Pfami PF00698. Acyl_transf_1. 1 hit.
[Graphical view ]
PIRSFi PIRSF000446. Mct. 1 hit.
SUPFAMi SSF52151. SSF52151. 2 hits.
SSF55048. SSF55048. 1 hit.
TIGRFAMsi TIGR00128. fabD. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MSSA476.

Entry informationi

Entry nameiFABD_STAAS
AccessioniPrimary (citable) accession number: Q6G9Y3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: July 19, 2004
Last modified: September 3, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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