Reviewed,
UniProtKB/Swiss-Prot Q6G9J4 (TYRA_STAAS)
Last modified
January 19, 2010.
Version 35.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Prephenate dehydrogenase Short name=PDH EC=1.3.1.12 | ||||
| Gene names |
| ||||
| Organism | Staphylococcus aureus (strain MSSA476) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 282459 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Staphylococcus |
Protein attributes
| Sequence length | 363 AA. |
| Sequence status | Complete. |
| Protein existence | Predicted. |
General annotation (Comments)
| Catalytic activity | Prephenate + NAD+ = 4-hydroxyphenylpyruvate + CO2 + NADH. |
| Pathway | |
| Sequence similarities | Contains 1 prephenate/arogenate dehydrogenase domain. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Aromatic amino acid biosynthesis Tyrosine biosynthesis |
| Ligand | NAD |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tyrosine biosynthetic processInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | binding Inferred from electronic annotation. Source: InterPro prephenate dehydrogenase (NADP+) activityInferred from electronic annotation. Source: InterPro prephenate dehydrogenase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance." Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J., Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A., Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C., Clark L., Corton C. Parkhill J.Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004) [PubMed: 15213324] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BX571857 Genomic DNA. Translation: CAG43082.1. |
| RefSeq | YP_043429.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 2G5C based on UniProtKB O67636. |
| SMR | Q6G9J4. Positions 3-295. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q6G9J4. |
Genome annotation databases | |
| GeneID | 2861989. |
| GenomeReviews | Gene locus SAS1305 in contig BX571857_GR. |
| KEGG | sas:SAS1305. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0287. |
| HOGENOM | HBG544990. |
| OMA | QRAIRWG. |
Enzyme and pathway databases | |
| BioCyc | SAUR282459:SAS1305-MONOMER. |
Family and domain databases | |
| InterPro | IPR016040. NAD(P)-bd_dom. IPR003099. Prephen_DH. [Graphical view] |
| PANTHER | PTHR21363. Prephen_DH. 1 hit. |
| Pfam | PF02153. PDH. 1 hit. [Graphical view] |
| PROSITE | PS51176. PDH_ADH. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | TYRA_STAAS | ||||||||
| Accession | Primary (citable) accession number: Q6G9J4 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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