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Protein

Probable CtpA-like serine protease

Gene

SAS1363

Organism
Staphylococcus aureus (strain MSSA476)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei329Charge relay systemBy similarity1
Active sitei340Charge relay systemBy similarity1
Active sitei354Charge relay systemBy similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Serine protease

Enzyme and pathway databases

BioCyciSAUR282459:G13EH-1386-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable CtpA-like serine protease (EC:3.4.21.-)
Gene namesi
Ordered Locus Names:SAS1363
OrganismiStaphylococcus aureus (strain MSSA476)
Taxonomic identifieri282459 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei39 – 59HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002331931 – 496Probable CtpA-like serine proteaseAdd BLAST496

Structurei

3D structure databases

ProteinModelPortaliQ6G9E1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini124 – 206PDZPROSITE-ProRule annotationAdd BLAST83

Sequence similaritiesi

Belongs to the peptidase S41A family.Curated
Contains 1 PDZ (DHR) domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000038765.
KOiK03797.
OMAiLKMASIF.

Family and domain databases

Gene3Di1.10.101.10. 1 hit.
2.30.42.10. 1 hit.
3.90.226.10. 2 hits.
InterProiIPR029045. ClpP/crotonase-like_dom.
IPR001478. PDZ.
IPR004447. Peptidase_S41A.
IPR002477. Peptidoglycan-bd-like.
IPR005151. Tail-specific_protease.
[Graphical view]
PfamiPF13180. PDZ_2. 1 hit.
PF03572. Peptidase_S41. 1 hit.
PF01471. PG_binding_1. 1 hit.
[Graphical view]
SMARTiSM00228. PDZ. 1 hit.
SM00245. TSPc. 1 hit.
[Graphical view]
SUPFAMiSSF47090. SSF47090. 1 hit.
SSF50156. SSF50156. 1 hit.
SSF52096. SSF52096. 2 hits.
TIGRFAMsiTIGR00225. prc. 1 hit.
PROSITEiPS50106. PDZ. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6G9E1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDDKQHTSSS DDERAEIATS NQDQETNSSK RVHLKRWQFI SILIGTILIT
60 70 80 90 100
AVITVVAYIF INQKISGLNK TDQANLNKIE NVYKILNSDY YKKQDSDKLS
110 120 130 140 150
KAAIDGMVKE LKDPYSEYLT KEQTKSFNEG VSGDFVGIGA EMQKKNDQIM
160 170 180 190 200
VTSPMKGSPA ERAGIRPKDV ITKVNGKSIK GKALDEVVKD VRGKENTEVT
210 220 230 240 250
LTVQRGSEEK DVKIKREKIH VKSVEYKKKG KVGVITINKF QNDTSGELKD
260 270 280 290 300
AVLKAHKDGL KKIVLDLRNN PGGLLDEAVK MANIFIDKGK TVVKLEKGKD
310 320 330 340 350
TEAIQTSNDA LKEAKDMDIS ILVNEGSASA SEVFTGALKD YNKAKVYGSK
360 370 380 390 400
TFGKGVVQTT REFKDGSLLK YTEMKWLTPD GHYIHGKGIK PDVTIDTPKY
410 420 430 440 450
QSLNVIPNTK TFKVGDDDKN IKTIKIGLSA LGYKVDNETT QFDQALENQV
460 470 480 490
KAFQQANKLE VTGEFNKETN NKFTELLVEK ANKHDDVLDK LINILK
Length:496
Mass (Da):55,275
Last modified:July 19, 2004 - v1
Checksum:i9A41BE6069218604
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571857 Genomic DNA. Translation: CAG43139.1.
RefSeqiWP_000342126.1. NC_002953.3.

Genome annotation databases

KEGGisas:SAS1363.
PATRICi19552193. VBIStaAur96780_1415.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571857 Genomic DNA. Translation: CAG43139.1.
RefSeqiWP_000342126.1. NC_002953.3.

3D structure databases

ProteinModelPortaliQ6G9E1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

KEGGisas:SAS1363.
PATRICi19552193. VBIStaAur96780_1415.

Phylogenomic databases

HOGENOMiHOG000038765.
KOiK03797.
OMAiLKMASIF.

Enzyme and pathway databases

BioCyciSAUR282459:G13EH-1386-MONOMER.

Family and domain databases

Gene3Di1.10.101.10. 1 hit.
2.30.42.10. 1 hit.
3.90.226.10. 2 hits.
InterProiIPR029045. ClpP/crotonase-like_dom.
IPR001478. PDZ.
IPR004447. Peptidase_S41A.
IPR002477. Peptidoglycan-bd-like.
IPR005151. Tail-specific_protease.
[Graphical view]
PfamiPF13180. PDZ_2. 1 hit.
PF03572. Peptidase_S41. 1 hit.
PF01471. PG_binding_1. 1 hit.
[Graphical view]
SMARTiSM00228. PDZ. 1 hit.
SM00245. TSPc. 1 hit.
[Graphical view]
SUPFAMiSSF47090. SSF47090. 1 hit.
SSF50156. SSF50156. 1 hit.
SSF52096. SSF52096. 2 hits.
TIGRFAMsiTIGR00225. prc. 1 hit.
PROSITEiPS50106. PDZ. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCTPAL_STAAS
AccessioniPrimary (citable) accession number: Q6G9E1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 2, 2006
Last sequence update: July 19, 2004
Last modified: November 2, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.