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Q6G7J5

- PTPB_STAAS

UniProt

Q6G7J5 - PTPB_STAAS

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Protein

Low molecular weight protein-tyrosine-phosphatase PtpB

Gene
ptpB, SAS2018
Organism
Staphylococcus aureus (strain MSSA476)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Dephosphorylates the phosphotyrosine-containing proteins By similarity.

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei7 – 71Nucleophile By similarity
Active sitei13 – 131 By similarity
Active sitei111 – 1111Proton donor By similarity

GO - Molecular functioni

  1. protein tyrosine phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Low molecular weight protein-tyrosine-phosphatase PtpB (EC:3.1.3.48)
Alternative name(s):
Phosphotyrosine phosphatase B
Short name:
PTPase B
Gene namesi
Name:ptpB
Ordered Locus Names:SAS2018
OrganismiStaphylococcus aureus (strain MSSA476)
Taxonomic identifieri282459 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000002201: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 139139Low molecular weight protein-tyrosine-phosphatase PtpBPRO_0000300674Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi282459.SAS2018.

Structurei

3D structure databases

ProteinModelPortaliQ6G7J5.
SMRiQ6G7J5. Positions 1-134.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0394.
HOGENOMiHOG000273091.
KOiK01104.
OMAiPMAMALL.
OrthoDBiEOG6MH5JB.

Family and domain databases

InterProiIPR023485. Ptyr_pPase_SF.
IPR000106. Tyr_phospatase/Ars_reductase.
IPR017867. Tyr_phospatase_low_mol_wt.
[Graphical view]
PANTHERiPTHR11717. PTHR11717. 1 hit.
PfamiPF01451. LMWPc. 1 hit.
[Graphical view]
PRINTSiPR00719. LMWPTPASE.
SMARTiSM00226. LMWPc. 1 hit.
[Graphical view]
SUPFAMiSSF52788. SSF52788. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6G7J5-1 [UniParc]FASTAAdd to Basket

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MKILFVCTGN TCRSPLAESI AKEVMPNHQF ESRGIFAVNN QGVSNYVEDL    50
VEEHHLAETT LSQQFTEADL KADIILTMSY SHKELIEAHF GLQNHVFTLH 100
EYVKEAGEVI DPYGGTKEMY VHTYEELVSL ILKLKDIIC 139
Length:139
Mass (Da):15,788
Last modified:July 19, 2004 - v1
Checksum:i63EB2C0E2A53EA5B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571857 Genomic DNA. Translation: CAG43826.1.
RefSeqiYP_044129.1. NC_002953.3.

Genome annotation databases

GeneIDi2864105.
KEGGisas:SAS2018.
PATRICi19553647. VBIStaAur96780_2100.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571857 Genomic DNA. Translation: CAG43826.1 .
RefSeqi YP_044129.1. NC_002953.3.

3D structure databases

ProteinModelPortali Q6G7J5.
SMRi Q6G7J5. Positions 1-134.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 282459.SAS2018.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 2864105.
KEGGi sas:SAS2018.
PATRICi 19553647. VBIStaAur96780_2100.

Phylogenomic databases

eggNOGi COG0394.
HOGENOMi HOG000273091.
KOi K01104.
OMAi PMAMALL.
OrthoDBi EOG6MH5JB.

Family and domain databases

InterProi IPR023485. Ptyr_pPase_SF.
IPR000106. Tyr_phospatase/Ars_reductase.
IPR017867. Tyr_phospatase_low_mol_wt.
[Graphical view ]
PANTHERi PTHR11717. PTHR11717. 1 hit.
Pfami PF01451. LMWPc. 1 hit.
[Graphical view ]
PRINTSi PR00719. LMWPTPASE.
SMARTi SM00226. LMWPc. 1 hit.
[Graphical view ]
SUPFAMi SSF52788. SSF52788. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MSSA476.

Entry informationi

Entry nameiPTPB_STAAS
AccessioniPrimary (citable) accession number: Q6G7J5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: July 19, 2004
Last modified: June 11, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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