Q6G6B5 (Q6G6B5_STAAS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
D-isomer specific 2-hydroxyacid dehydrogenase EMBL CAG44261.1

Gene names

Ordered Locus Names:

SAS2445

Organism

Staphylococcus aureus (strain MSSA476) [Complete proteome] [HAMAP]

Taxonomic identifier

282459 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	332 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. RuleBase RU003719

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU003720
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	NAD binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6G6B5 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: 2E011A32CAA52416	FASTA	332	37,247
	10 20 30 40 50 60 MTKIKIMSVR DEDMPYIKAW AEKHHVEVDI TKEALTDDNV EGVAGYDGLS LSQQIPLSEH 70 80 90 100 110 120 VYKRLNELDI KQIAQRSAGF DTYDLELANK YNLIVSNVPS YSPNSIAEFA VNQAINVVRH 130 140 150 160 170 180 FNQIQTKVRE HDFRWEPTIL SKSIKDLKVA VIGTGRIGRV VADIFANGYQ SDVVAYDPFP 190 200 210 220 230 240 NAKIATYVDY KDTIEEAVEG ADIVTLHVPA TKYNHYLFNA ELFKHFKKGA VFVNCARGSL 250 260 270 280 290 300 VDTKALLDAL DNGVIKGAAL DTYEFERKLF PSDQRGKTLN DPLLESLIDR EDVILTPHIA 310 320 330 FYTEAAVKNL IVDALDATLD VLQTGDTRLR VN

References

[1]

"Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance." Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J., Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A., Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C., Clark L., Corton C. , Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z., Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N., Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M., Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J. Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004) [PubMed: 15213324] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX571857 Genomic DNA. Translation: CAG44261.1.
RefSeq	YP_044559.1. NC_002953.3.
3D structure databases
ProteinModelPortal	Q6G6B5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6G6B5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000023576; EBSTAP00000022743; EBSTAG00000023575.
GeneID	2861863.
GenomeReviews	Gene locus SAS2445 in contig BX571857_GR.
KEGG	sas:SAS2445.
PATRIC	19554558. VBIStaAur96780_2548.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1052.
GeneTree	EBGT00050000024534.
HOGENOM	HBG731446.
OMA	EMVHQSF.
ProtClustDB	PRK08605.
Enzyme and pathway databases
BioCyc	SAUR282459:SAS2445-MONOMER.
Family and domain databases
InterPro	IPR006139. D-isomer_2_OHA_DH_cat_dom. IPR006140. D-isomer_2_OHA_DH_NAD-bd. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 2 hits.
KO	K03778.
Pfam	PF00389. 2-Hacid_dh. 1 hit. PF02826. 2-Hacid_dh_C. 1 hit. [Graphical view]
PROSITE	PS00065. D_2_HYDROXYACID_DH_1. 1 hit. PS00670. D_2_HYDROXYACID_DH_2. 1 hit. PS00671. D_2_HYDROXYACID_DH_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6G6B5_STAAS

Accession

Primary (citable) accession number: Q6G6B5

Entry history

Integrated into UniProtKB/TrEMBL:	July 19, 2004
Last sequence update:	July 19, 2004
Last modified:	December 14, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)